Results 31 to 40 of about 6,827 (117)
Heat shock protein 90 inhibitor RGRN-305 potently attenuates skin inflammation
Frontiers in Immunology, 2023 IntroductionChronic inflammatory skin diseases may have a profound negative impact on the quality of life. Current treatment options may be inadequate, offering an unsatisfactory response or side effects.
Hakim Ben Abdallah +6 more
doaj +1 more source
Individual Keratinocyte Necroses in the Epidermis Are Apoptotic Keratinocytes in the Skin
Diagnostics, 2023 The patient was a 44-year-old woman with Stevens–Johnson syndrome due to receiving Baktar® (sulfamethoxazole trimethoprim) medication at our outpatient dermatology clinic. The epidermis, dermis, and subcutaneous adipose tissue samples showed numerous necrotic keratinocytes in the epidermis.
Mitsuhiro Tachibana +3 more
openaire +3 more sources
Korean red ginseng extracts alleviate skin damage in heat-stimulated skin cells by suppressing NF-κB activation [PDF]
Archives of Biological SciencesThis study explored the impact of heat stimulation on skin barrier damage, aging, and inflammatory responses by analyzing gene and protein-level changes.
Kim Jeeyoung +4 more
doaj +1 more source
Frontiers in Medicine, 2023 BackgroundThe incidence of diabetes-related wounds is widespread, and the treatment is challenging. We found that Moist Exposed Burn Ointment (MEBO) promotes the healing of diabetes-related wounds, but the mechanism is not clear.MethodsThis study aimed ...
Yuanxun Gong +6 more
doaj +1 more source
Keratinocyte Growth Factor Promotes Melanosome Transfer to Keratinocytes [PDF]
Journal of Investigative Dermatology, 2005 Melanogenesis and melanosome transfer from the melanocytes to the neighboring keratinocytes are induced by ultraviolet radiation and modulated by autocrine and paracrine factors. Keratinocyte growth factor (KGF/fibroblast growth factor (FGF)7) is a paracrine mediator of human keratinocyte growth and differentiation. We evaluated the influence of KGF on
CARDINALI G +6 more
openaire +4 more sources
Frontiers in Pharmacology, 2023 Background: Exposure to ultraviolet B (UVB) radiation can damage the epidermis barrier function and eventually result in skin dryness. At present, little work is being devoted to skin dryness.
Lusheng Wang +10 more
doaj +1 more source
Mediators of Inflammation, 2019 The interaction between tumor necrosis factor- (TNF-) like weak inducer of apoptosis (TWEAK) and fibroblast growth factor-inducible 14 (Fn14) regulates the fate of keratinocytes, depending on the relative expression of TNF receptor (TNFR) 1 or TNFR2 ...
Xuening Wang +7 more
doaj +1 more source
Induction of autophagy improves skin and hair conditions in dogs with underlying diseases
Frontiers in Veterinary Science, 2023 BackgroundAutophagy was reported to play a crucial role in maintaining general and skin health.MethodsThe study used a synthesized autophagy inducer (AI) (Aquatide™ cospharm Inc.; Daejeon, Korea), for evaluating the effects of autophagy on skin and hair ...
Yoonji Kim +7 more
doaj +1 more source
European Journal of Histochemistry, 2022 Psoriasis is a chronic inflammatory skin disease. Although miRNAs are reported to be associated with the pathogenesis of psoriasis, the contribution of individual microRNAs toward psoriasis remains unclear. The miR-17-92 cluster regulates cell growth and
Qingwen Li +5 more
doaj +1 more source
eLife, 2021 Gene knockout of the master regulator of mitochondrial fission, Drp1, prevents neoplastic transformation. Also, mitochondrial fission and its opposing process of mitochondrial fusion are emerging as crucial regulators of stemness.
Brian Spurlock +9 more
doaj +1 more source