Results 81 to 90 of about 322,086 (387)

Long noncoding RNA lincRNA-p21 is the major mediator of UVB-induced and p53-dependent apoptosis in keratinocytes

Cell Death and Disease, 2015
LincRNA-p21 is a long noncoding RNA and a transcriptional target of p53 and HIF-1α. LincRNA-p21 regulates gene expression in cis and trans, mRNA translation, protein stability, the Warburg effect, and p53-dependent apoptosis and cell cycle arrest in ...
Jonathan R. Hall, Zachary J. Messenger, Hann W. Tam, Suzanne L. Phillips, L. Recio, R. Smart   +5 more
semanticscholar   +1 more source

Dyslipidemia initiates keratinocytes proliferation through upregulation of lncRNA NEAT in psoriasis patients [PDF]

, 2023
Abeer Mostafa, Dina Sabry, Nesreen M. Aboraia, Ahmed Fawzy, Amany A. Abou-Elalla   +4 more
openalex   +1 more source

An Ionic Gelation Powder for Ultrafast Hemostasis and Accelerated Wound Healing

Advanced Functional Materials, EarlyView.
An ultrafast ionic gelation‐activated hemostatic powder (AGCL) forms a hydrogel within ≈1 s upon contact with blood‐derived calcium ions. The AGCL powder enables rapid hemorrhage control, strong tissue adhesion, and enhanced healing. The powder's pre‐crosslinked polymer network ensures high blood uptake and stability, offering effective treatment for ...
Youngju Son, Kyusoon Pak, Taehoon Lee, Monica Celine Prayogo, Jinyoung Choi, Sukkyung Kang, Minjoo Kang, Byungkook Oh, Sang Yu Sun, Sanha Kim, Sung Gap Im, Sangyong Jon, Steve Park   +12 more
wiley   +1 more source

Features of the apoptosis markers expression by skin cell with ageing

Бюллетень сибирской медицины, 2008
The immunohistochemical study of skin was conducted to verify presence of p53, bcl-2 and bax apoptosis markers in epidermal keratinocytes of patients from two age groups: 16 to 44 years old and 45 to 64 years old.
T. Yu. Vitruk, N. V. Ryazantseva, P. N. Pesterev, L. R. Mustafina   +3 more
doaj   +1 more source

Skin microbiota: a source of disease or defence?

, 2008
Microbes found on the skin are usually regarded as pathogens, potential pathogens or innocuous symbiotic organisms. Advances in microbiology and immunology are revising our understanding of the molecular mechanisms of microbial virulence and the specific
Cogen, AL, Gallo, RL, Nizet, V
core   +1 more source

Randomized trial of calcipotriol combined with 5-fluorouracil for skin cancer precursor immunotherapy [PDF]

, 2017
BACKGROUND. Actinic keratosis is a precursor to cutaneous squamous cell carcinoma. Long treatment durations and severe side effects have limited the efficacy of current actinic keratosis treatments.
Ahu Turkoz, Andras Schaffer, Arturo P. Saavedra, Cipolat, Fenske, Hengameh Mirzaalian, Jean-Pierre Eliane, Lynn A. Cornelius, Mary Tabacchi, Michael Wallendorf, Raphael Kopan, Salasche, Sara Moradi Tuchayi, Seckin, Shadmehr Demehri, Sindhu Manivasagam, Stockfleth, Trevor J. Cunningham, Warino   +18 more
core   +2 more sources

Resveratrol Prevents Oxidative Stress-Induced Senescence and Proliferative Dysfunction by Activating the AMPK-FOXO3 Cascade in Cultured Primary Human Keratinocytes

PLoS ONE, 2015
The aging process is perceived as resulting from a combination of intrinsic factors such as changes in intracellular signaling and extrinsic factors, most notably environmental stressors.
Y. Ido, A. Duranton, Fan Lan, Karen A Weikel, L. Breton, N. Ruderman   +5 more
semanticscholar   +1 more source

An Ultrafast Self‐Gelling Versatile Hydrogel for Rapid Infected Burn Wound Repair in Military Medicine

Advanced Functional Materials, EarlyView.
A self‐gelling PG@PAC (POD/Gel‐CDH@PA/CHX) powder is developed for infected burn care in austere settings. Upon contact with wound exudate, it instantly forms an adhesive hydrogel, providing simultaneous hemostasis, broad‐spectrum antibacterial activity, reactive oxygen species scavenging, and immunomodulation. In a murine model of S.
Liping Zhang, Zhangrui Wu, Xiansheng Zhao, Geng Wang, Quyang Yang, Minxia zhang, Xiaowei Wang, Xiujun Cheng, Changyue Wu, Dan Wu, Yutian Yang, Canbin Dong, Tao Zhang, Weiqiang Tan, Ningwen Zhu   +14 more
wiley   +1 more source

Korean red ginseng extracts alleviate skin damage in heat-stimulated skin cells by suppressing NF-κB activation [PDF]

Archives of Biological Sciences
This study explored the impact of heat stimulation on skin barrier damage, aging, and inflammatory responses by analyzing gene and protein-level changes.
Kim Jeeyoung, Bang Weon Jeong, Joo Yung Hyup, Lee Sung Hyeon, Lee Chang-Seok   +4 more
doaj   +1 more source

Exposure of Human Skin Organoids to Low Genotoxic Stress Can Promote Epithelial-to-Mesenchymal Transition in Regenerating Keratinocyte Precursor Cells

Cells, 2020
For the general population, medical diagnosis is a major cause of exposure to low genotoxic stress, as various imaging techniques deliver low doses of ionizing radiation.
Sophie Cavallero, Renata Neves Granito, Daniel Stockholm, Peggy Azzolin, Michèle T. Martin, Nicolas O. Fortunel   +5 more
doaj   +1 more source