Results 141 to 150 of about 134,704 (353)

Fabrication of Polypyrrole–Polystyrene Sulfonate by Amperometric Biosensor‐Based Electropolymerization for Cholesterol Determination in Serum

open access: yesBiotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Since cholesterol triggers many diseases, many methods have been developed for its determination. In this study, an alternative system for cholesterol determination was developed by preparing amperometric biosensors. In the development of the biosensor, Pt/polypyrrole–polystyrene sulfonate film was prepared by electropolymerization of ...
Alaa Anwer Ali Dada   +3 more
wiley   +1 more source

Mechanism of kidney adaption in simulated high-altitude

open access: yesLinchuang shenzangbing zazhi
High altitude is an independent risk factor for acute kidney injury (AKI). In early stage, normal kidneys may modulate their functions and structures to adapt to a high plateau. Individuals progressing to AKI have a higher mortality.
Dan Xiao   +3 more
doaj   +1 more source

Complex Interplay of Metabolic Substrates, Points of Entry into the Mitochondrial Electron Chain, and ROS Generation

open access: yesBioEssays, EarlyView.
Recently, Singh et al. studied the influence of reactive oxygen species (ROS) formation by the ETC on mitochondrial morphology in baker's yeast. Their findings highlight evolutionary constraints, important trade‐offs using different metabolic substrates, and connections with points of entry into the ETC, ROS production, the FADH2/NADH ratio concept ...
Dave Speijer
wiley   +1 more source

Theoretical Analysis of d‐Serine and d‐Asparagine as Biomarkers for Glomerular Filtration Rate

open access: yesChemistry &Biodiversity, EarlyView.
ABSTRACT Chronic kidney disease (CKD) is a major global health issue, requiring accurate and noninvasive renal function assessment. Glomerular filtration rate (GFR) is the standard measure, but current methods, including inulin clearance and creatinine‐based estimation, have limitations in accuracy, invasiveness, and practicality.
Ryo Tanaka   +3 more
wiley   +1 more source

Identification of Urinary Activin A as a Novel Biomarker Reflecting the Severity of Acute Kidney Injury [PDF]

open access: yes, 2018
学位記番号 ...
Takahashi, Shunsuke   +2 more
core  

Manganese Neurotoxicity and Familial Disorders of Manganese Transport

open access: yesAnnals of the Child Neurology Society, EarlyView.
ABSTRACT Manganese is the 12th most common element in the Earth's crust and is an essential industrial component. Biologically, this metal plays an important role as a constituent of numerous enzymes. While manganese is required for normal biochemical and physiological processes, manganese excess can lead to significant toxicity, particularly to the ...
Sidney M. Gospe Jr.
wiley   +1 more source

Physiology of renal glucose handling via SGLT1, SGLT2 and GLUT2. [PDF]

open access: yes, 2018
The concentration of glucose in plasma is held within narrow limits (4-10 mmol/l), primarily to ensure fuel supply to the brain. Kidneys play a role in glucose homeostasis in the body by ensuring that glucose is not lost in the urine.
Ghezzi, Chiara   +2 more
core  

Changes in Protein Expression of Renal Drug Transporters and Drug‐Metabolizing Enzymes in Autosomal Dominant Polycystic Kidney Disease Patients

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Autosomal dominant polycystic kidney disease is the most prevalent inherited kidney disease and leads to bilateral kidney enlargement and progressive loss of renal function, often over decades. Comorbidities include hypertension, flank pain, and bacterial infections. The condition often necessitates prolonged multidrug therapy.
Annika C. Tillmann   +6 more
wiley   +1 more source

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