Results 161 to 170 of about 1,118,511 (368)

Relationships Between Serum Vitamin D, Inflammatory Markers, and Outcomes in Non‐Critically Ill Patients With COVID‐19: A Cross‐Sectional Study

open access: yesMedicine Advances, EarlyView.
Serum urea levels have been identified as a significant predictor of in‐hospital mortality in COVID‐19 patients, whereas vitamin D deficiency correlates with elevated inflammatory markers such as CRP and RPR. To better understand these associations and their implications for clinical outcomes, further large‐scale studies are warranted, emphasizing the ...
Zahra Khorasanchi   +13 more
wiley   +1 more source

BMP-7 Protein Expression Is Downregulated in Human Diabetic Nephropathy

open access: yesActa Clinica Croatica, 2015
Bone morphogenetic protein-7 (BMP-7) is expressed in all parts of the normal kidney parenchyma, being highest in the epithelium of proximal tubules. It protects kidney against acute and chronic injury, inflammation and fibrosis.
Renata Ivanac-Janković   +5 more
doaj  

Nephroprotective Effects of Fraxinus Hookeri Wenz. Against Renal Toxicity and DNA Oxidative Damages Induced by CCl4 in Rats

open access: yesChemistryOpen, EarlyView.
This study evaluates the nephroprotective potential of Fraxinus hookeri Wenz. (F. hookeri), a medicinal plant of the Oleaceae family, against CCl4‐induced oxidative stress. The findings demonstrate its ability to restore antioxidant defenses, renal function markers, and DNA integrity while reducing lipid peroxidation and histopathological damage.
Raheela Sarwar   +9 more
wiley   +1 more source

Wilms Tumor in Children with AMER1/WTX Germline Pathogenic Variants: A Multicenter Case Series

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background 10–15% of children with Wilms tumor (WT) have predisposing genetic syndromes. Somatic mutations are frequently identified; however, germline pathogenic variants in AMER1 are much less prevalent and are associated with osteopathia striata with cranial sclerosis (OSCS).
Insiyah Campwala   +9 more
wiley   +1 more source

Elevated Bromide Levels due to Tazemetostat Therapy Treated With Salt and Water Supplementation in Two Children With Atypical Teratoid Rhabdoid Tumor

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Atypical teratoid rhabdoid tumor (ATRT) is an embryonal CNS tumor that afflicts young children. The molecular process associated with ATRT is loss of SMARCB1 or SMARCA4, which causes EZH2 overactivation. Tazemetostat hydrobromide is an EZH2 inhibitor, which has shown efficacy in the treatment of ATRT. Tazemetostat is produced as a bromide salt
Thomas J. Galletta   +5 more
wiley   +1 more source

Tissue‐Specific Regulation of Fatty Acid Metabolism in a Mouse Model of Isolated Complex I Deficiency

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Isolated complex I deficiency (ICD) is commonly associated with mitochondrial diseases and closely mimics subacute necrotising encephalomyelopathy. This disorder is characterised by metabolic perturbations that affect energy metabolism pathways, including fatty acid metabolism.
Sibonelo Glen Khumalo   +2 more
wiley   +1 more source

Structural requirements for protection by small amino acids against hypoxic injury in kidney proximal tubules 1 [PDF]

open access: green, 1990
Joel M. Weinberg   +4 more
openalex   +1 more source

Vertebrate kidney tubules elongate using a planar cell polarity–dependent, rosette-based mechanism of convergent extension

open access: yesNature Genetics, 2012
S. Lienkamp   +6 more
semanticscholar   +1 more source

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