Results 271 to 280 of about 3,771,587 (392)

Imatinib-induced rhabdomyolysis: A case report. [PDF]

Leuk Res Rep
Rubenstein J, Schwartz SM, Vankawala J, Caplan M, Shea S, Jurcic JG.   +5 more
europepmc   +1 more source

MAP kinase kinase kinase 7 (MAP3K7; TAK1) [PDF]

Science-Business eXchange, 2011
openaire   +1 more source

Mammalian thioredoxin is a direct inhibitor of apoptosis signal‐regulating kinase (ASK) 1

EMBO Journal, 1998
M. Saitoh, H. Nishitoh, M. Fujii, K. Takeda, K. Tobiume, Yasuhiro Sawada, M. Kawabata, K. Miyazono, H. Ichijo   +8 more
semanticscholar   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

Phosphorylation of a conserved aspartate in the catalytic site of eukaryotic elongation factor 2 kinase. [PDF]

Protein Sci
Piserchio A, Isiorho EA, Abzalimov R, Dalby KN, Ghose R.   +4 more
europepmc   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

In-silico identification, characterization and expression analysis of salt overly sensitive-2 (SOS2) gene family in Gossypium hirsutum L. against abiotic stresses. [PDF]

Sci Rep
Iqra L, Shahid MN, Ali Q.
europepmc   +1 more source

MAP kinase kinase kinase 14 (MAP3K14; NIK) [PDF]

Science-Business eXchange, 2012
openaire   +1 more source

Regulation of endothelium-derived nitric oxide production by the protein kinase Akt

Nature, 1999
D. Fulton, J. Gratton, T. Mccabe, J. Fontana, Y. Fujio, K. Walsh, T. Franke, A. Papapetropoulos, W. Sessa   +8 more
semanticscholar   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source