Results 161 to 170 of about 8,462,139 (217)

Small-Molecule Control of Kinesin-5 Proteins

, 2008
Mitosis, or cell division, is the mechanism by which cells divide and is an intricate process requiring the action and control of numerous proteins.
Learman, Sarah Sebring
core  

A Chimeric Kinesin-1 Head/Kinesin-5 Tail Motor Switches between Diffusive and Processive Motility

, 2013
Homotetrameric kinesin-5 motors are essential for chromosome separation and assembly of the mitotic spindle. These kinesins bind between two microtubules (MTs) and slide them apart, toward the spindle poles.
Wessel, Alok D., Kramer, Stefanie, Schmidt, Christoph F., Lakaemper, Stefan, Thiede, Christina, Lakämper, Stefan, Schmidt, Christoph   +6 more
core   +1 more source

Kinesin-3 and dynein cooperate in long-range retrograde endosome motility along a nonuniform microtubule array

, 2011
The polarity of microtubules (MTs) determines the motors for intracellular motility, with kinesins moving to plus ends and dynein to minus ends. In elongated cells of Ustilago maydis, dynein is thought to move early endosomes (EEs) toward the septum ...
S Kilaru (19426795), G Steinberg (13284030), J Collemare (21925268), G Fink (13609282), M Schuster (7676525), Y Roger (21845105)   +5 more
core  

Drag-induced directionality switching of kinesin-5 Cin8 revealed by cluster-motility analysis. [PDF]

Sci Adv, 2021
Pandey H, Reithmann E, Goldstein-Levitin A, Al-Bassam J, Frey E, Gheber L.   +5 more
europepmc   +1 more source

Inter-organelle interactions between the ER and mitotic spindle facilitates Zika protease cleavage of human Kinesin-5 and results in mitotic defects. [PDF]

iScience, 2021
Liu L, Downs M, Guidry J, Wojcik EJ.
europepmc   +1 more source

Molecular Dynamics Simulations Provide Further Insights into the Allosteric Regulation of the Kinesin-5 Motor Domain by Loop 5. [PDF]

J Chem Inf Model
Rodríguez-Santos G, Bonollo G, Sciva C, Colombo G, Pérez-Melero C, Serapian SA.   +5 more
europepmc   +1 more source

PP6 phosphatase and Elongator contribute to kinesin 5-dependent spindle assembly by controlling microtubule regulators levels. [PDF]

PLoS Genet
Marín L, Castro-Sangrador J, Hoya M, Tello S, Coll PM, Encinar Del Dedo J, Fernández-Álvarez A, Ribas JC, Tran PT, Rincon SA.   +9 more
europepmc   +1 more source

Selective regulation of kinesin-5 function by β-tubulin carboxy-terminal tails. [PDF]

J Cell Biol
Thomas EC, Moore JK.
europepmc   +1 more source

Elucidating the interactions between Kinesin-5/BimC and the microtubule: insights from TIRF microscopy and molecular dynamics simulations. [PDF]

Brief Bioinform
Guo W, Gao Y, Du D, Sanchez JE, Li Y, Qiu W, Li L.   +6 more
europepmc   +1 more source

Structure of Microtubule-Trapped Human Kinesin-5 and Its Mechanism of Inhibition Revealed Using Cryoelectron Microscopy.

Structure, 2021
Peña A, Sweeney A, Cook AD, Locke J, Topf M, Moores CA.   +5 more
europepmc   +1 more source