Results 11 to 20 of about 51,301 (248)
The mechanism of kinesin inhibition by kinesin-binding protein [PDF]
eLife, 2020 Subcellular compartmentalisation is necessary for eukaryotic cell function. Spatial and temporal regulation of kinesin activity is essential for building these local environments via control of intracellular cargo distribution.
Joseph Atherton +8 more
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Electrostatically biased binding of kinesin to microtubules. [PDF]
PLoS Biology, 2011 The minimum motor domain of kinesin-1 is a single head. Recent evidence suggests that such minimal motor domains generate force by a biased binding mechanism, in which they preferentially select binding sites on the microtubule that lie ahead in the ...
Barry J Grant +7 more
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CytoskeletonABSTRACT Few proteins have inspired as much curiosity as kinesin. Since its discovery 40 years ago, kinesin has become one of the best understood molecular machines in biology, yet it continues to reveal new questions about how cells organize and move their contents.
Ronald D. Vale
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Kinesin transport: driving kinesin in the neuron [PDF]
Current Biology, 2001 A plethora of cytoplasmic motors contribute to the directed transport of a wide range of cellular organelles and molecules. Recent studies have advanced our understanding of cargo attachment to motor molecules and the regulation of intracellular transport.
Hays, Tom, Li, Min-gang
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The functions of kinesin and kinesin-related proteins in eukaryotes [PDF]
Cell Adhesion & Migration, 2020 Kinesins constitute a superfamily of ATP-driven microtubule motor enzymes that convert the chemical energy of ATP hydrolysis into mechanical work along microtubule tracks. Kinesins are found in all eukaryotic organisms and are essential to all eukaryotic cells, involved in diverse cellular functions such as microtubule dynamics and morphogenesis ...
Iftikhar Ali, Wei-Cai Yang
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Kinesins in spermatogenesis† [PDF]
Biology of Reproduction, 2017 Kinesins are essential for the proper function of many types of polar cells, including epithelial cells, neurons, and sperm. Spermatogenesis is closely associated with many different kinesins. These kinesins participate in several fundamental processes, including mitotic and meiotic division, essential organelle transport, and the biogenesis of ...
Dan-Dan, Ma, Da-Hui, Wang, Wan-Xi, Yang
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Journal of Cell Science, 2010 Kinesin was discovered in 1985 – 25 years ago – based on its motility in cytoplasm extruded from the giant axon of the squid ([Allen et al., 1982][1]; [Brady et al., 1982][2]; [Vale et al., 1985][3]).
Endow, Sharyn A +2 more
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owolff-MPImF/MINFLUX-tracking-of-Kinesin-1-2022: MINFLUX data processing and evaluation
, 2022 Matlab files for processing raw MINFLUX data using a fixed-curvature or sliding-curvature estimator. Additional files for detecting steps in noisy data and for determining the bound and unbound state of the labeled kinesin ...
MINFLUX tracking of kinesin-1 2022
core +1 more source
Nature, 1996 Chromosome segregation during mitosis depends on the action of the mitotic spindle, a self-organizing, bipolar protein machine which uses microtubules (MTs) and their associated motors. Members of the BimC subfamily of kinesin-related MT-motor proteins are believed to be essential for the formation and functioning of a normal bipolar spindle.
Kashina, A. S +5 more
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Recycling of kinesin-1 motors by diffusion after transport. [PDF]
PLoS ONE, 2013 Kinesin motors drive the long-distance anterograde transport of cellular components along microtubule tracks. Kinesin-dependent transport plays a critical role in neurogenesis and neuronal function due to the large distance separating the soma and nerve ...
T Lynne Blasius +3 more
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