Results 11 to 20 of about 47,063 (259)
Structures of kinesin and kinesin–microtubule interactions
Current Opinion in Cell Biology, 1999 Several X-ray crystal structures of kinesin motor domains have recently been solved at high resolution ( approximately 0.2-0.3 nm), in both their monomeric and dimeric states. They show the folding of the polypeptide chain and different arrangements of subunits in the dimer.
Mandelkow, Eckhard, Hoenger, Andreas
openaire +4 more sources
Kinesin transport: driving kinesin in the neuron [PDF]
Current Biology, 2001 A plethora of cytoplasmic motors contribute to the directed transport of a wide range of cellular organelles and molecules. Recent studies have advanced our understanding of cargo attachment to motor molecules and the regulation of intracellular transport.
Hays, Tom, Li, Min-gang
openaire +2 more sources
The functions of kinesin and kinesin-related proteins in eukaryotes [PDF]
Cell Adhesion & Migration, 2020 Kinesins constitute a superfamily of ATP-driven microtubule motor enzymes that convert the chemical energy of ATP hydrolysis into mechanical work along microtubule tracks. Kinesins are found in all eukaryotic organisms and are essential to all eukaryotic cells, involved in diverse cellular functions such as microtubule dynamics and morphogenesis ...
Iftikhar Ali, Wei-Cai Yang
openaire +3 more sources
Kinesins in spermatogenesis† [PDF]
Biology of Reproduction, 2017 Kinesins are essential for the proper function of many types of polar cells, including epithelial cells, neurons, and sperm. Spermatogenesis is closely associated with many different kinesins. These kinesins participate in several fundamental processes, including mitotic and meiotic division, essential organelle transport, and the biogenesis of ...
Dan-Dan, Ma, Da-Hui, Wang, Wan-Xi, Yang
openaire +2 more sources
Journal of Cell Science, 2010 Kinesin was discovered in 1985 – 25 years ago – based on its motility in cytoplasm extruded from the giant axon of the squid ([Allen et al., 1982][1]; [Brady et al., 1982][2]; [Vale et al., 1985][3]).
Endow, Sharyn A +2 more
openaire +3 more sources
Nature, 1996 Chromosome segregation during mitosis depends on the action of the mitotic spindle, a self-organizing, bipolar protein machine which uses microtubules (MTs) and their associated motors. Members of the BimC subfamily of kinesin-related MT-motor proteins are believed to be essential for the formation and functioning of a normal bipolar spindle.
Kashina, A. S +5 more
openaire +3 more sources
owolff-MPImF/MINFLUX-tracking-of-Kinesin-1-2022: MINFLUX data processing and evaluation
, 2022 Matlab files for processing raw MINFLUX data using a fixed-curvature or sliding-curvature estimator. Additional files for detecting steps in noisy data and for determining the bound and unbound state of the labeled kinesin ...
MINFLUX tracking of kinesin-1 2022
core +1 more source
Kinesin-14 : the roots of reversal [PDF]
, 2010 Kinesin-14 motor proteins step towards microtubule minus ends, in the opposite direction to other kinesins. Work on the still-enigmatic kinesin-14 mechanism published in BMC Structural Biology shows that the carboxyl terminus of the motor head undergoes ...
Cross, R. A. +2 more
core +1 more source
Kinesin as an Electrostatic Machine [PDF]
Journal of Biological Physics, 2006 Kinesin and related motor proteins utilize ATP fuel to propel themselves along the external surface of microtubules in a processive and directional fashion. We show that the observed step-like motion is possible through time varying charge distributions furnished by the ATP hydrolysis circle while the static charge configuration on the microtuble ...
Alva, Aleix +2 more
openaire +4 more sources
The kinesin-12 Kif15 is a processive track-switching tetramer [PDF]
, 2014 Kinesin-12 motors are a little studied branch of the kinesin superfamily with the human protein (Kif15) implicated in spindle mechanics and chromosome movement.
McHugh, Toni +9 more
core +1 more source