Results 41 to 50 of about 47,063 (259)
Kinesin-II motility under crowded conditions.
, 2020 A. Schematic of the in vitro motility assay. kinesin-II motors walk along the microtubules attached to the glass slide. The fluorescently labeled motor proteins are excited and imaged using TIRF microscopy. B.
Daniël M. Miedema (8447271) +5 more
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, 2022 Live cell imaging showing location of kinesin-13GFP (green) with respect to kinetochore marker NDC80Cherry (red) during asexual (A, B) and sexual (C, D) proliferative stages.
Anthony A. Holder (53358) +11 more
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Effects of Obstacles on the Dynamics of Kinesins, Including Velocity and Run Length, Predicted by a Model of Two Dimensional Motion. [PDF]
PLoS ONE, 2016 Kinesins are molecular motors which walk along microtubules by moving their heads to different binding sites. The motion of kinesin is realized by a conformational change in the structure of the kinesin molecule and by a diffusion of one of its two heads.
Woochul Nam, Bogdan I Epureanu
doaj +1 more source
A look into kinesin's powerhouse [PDF]
FEBS Letters, 2001 Kinesins are microtubule‐dependent motors that serve a multitude of cellular purposes. The conserved motor domain provides the energy required for these processes. Shortly after the solution of the first kinesin motor domain crystal structures the similarity to myosin and G‐proteins was noted.
openaire +2 more sources
MAPping out distribution routes for kinesin couriers
, 2013 In the crowded environment of eukaryotic cells, diffusion is an inefficient distribution mechanism for cellular components. Long-distance active transport is required and is performed by molecular motors including kinesins.
Moores, Carolyn A. +5 more
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Electro-detachment of kinesin motor domain from microtubule in silico
Computational and Structural Biotechnology Journal, 2023 Kinesin is a motor protein essential in cellular functions, such as intracellular transport and cell-division, as well as for enabling nanoscopic transport in bio-nanotechnology.
Jiří Průša, Michal Cifra
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Microtubule-regulating kinesins [PDF]
Current Biology, 2013 Kinesins can regulate microtubule dynamics? The conventional function of kinesins, much like a molecular freight train, is to transport cargo by motoring along a microtubule (MT) track. But there exists another class of kinesins whose job relates more to track maintenance than transportation.
Sturgill, Emma G., Ohi, Ryoma
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The developmental biology of kinesins
Developmental Biology, 2021 Kinesins are microtubule-based motor proteins that are well known for their key roles in cell biological processes ranging from cell division, to intracellular transport of mRNAs, proteins, vesicles, and organelles, and microtubule disassembly. Interestingly, many of the ~45 distinct kinesin genes in vertebrate genomes have also been associated with ...
Mia J. Konjikusic +2 more
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PLoS Pathogens, 2010 Vaccinia virus (VACV) uses microtubules for export of virions to the cell surface and this process requires the viral protein F12. Here we show that F12 has structural similarity to kinesin light chain (KLC), a subunit of the kinesin-1 motor that binds ...
Gareth W Morgan +5 more
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Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source