Results 31 to 40 of about 82,635 (293)
Cell Reports, 2019 Summary: The motor protein kinesin-1 plays an important role in polarized sorting of transport vesicles to the axon. However, the mechanism by which the axonal entry of kinesin-1-dependent cargo transport is regulated remains unclear.
Xingxiu Pan +9 more
doaj +1 more source
The preprophase band-associated kinesin-14 OsKCH2 is a processive minus-end-directed microtubule motor. [PDF]
, 2018 In animals and fungi, cytoplasmic dynein is a processive minus-end-directed motor that plays dominant roles in various intracellular processes. In contrast, land plants lack cytoplasmic dynein but contain many minus-end-directed kinesin-14s.
Bowen, Joel +7 more
core +3 more sources
Kinesin-3 motors are fine-tuned at the molecular level to endow distinct mechanical outputs
BMC Biology, 2022 Background Kinesin-3 family motors drive diverse cellular processes and have significant clinical importance. The ATPase cycle is integral to the processive motility of kinesin motors to drive long-distance intracellular transport.
Pushpanjali Soppina +6 more
doaj +1 more source
Functional modulation of IFT kinesins extends the sensory repertoire of ciliated neurons in Caenorhabditis elegans [PDF]
, 2006 The diversity of sensory cilia on Caenorhabditis elegans neurons allows the animal to detect a variety of sensory stimuli. Sensory cilia are assembled by intraflagellar transport (IFT) kinesins, which transport ciliary precursors, bound to IFT particles,
Evans, James E. +6 more
core +2 more sources
Length-dependent disassembly maintains four different flagellar lengths in Giardia. [PDF]
, 2019 With eight flagella of four different lengths, the parasitic protist Giardia is an ideal model to evaluate flagellar assembly and length regulation. To determine how four different flagellar lengths are maintained, we used live-cell quantitative imaging ...
Aurrecoechea +69 more
core +2 more sources
Nature, 1996 Chromosome segregation during mitosis depends on the action of the mitotic spindle, a self-organizing, bipolar protein machine which uses microtubules (MTs) and their associated motors. Members of the BimC subfamily of kinesin-related MT-motor proteins are believed to be essential for the formation and functioning of a normal bipolar spindle.
Kashina, A. S +5 more
openaire +3 more sources
Universal and unique features of kinesin motors: Insights from a comparison of fungal and animal conventional kinesins [PDF]
, 1999 Kinesins are microtubule motors that use the energy derived from the hydrolysis of ATP to move unidirectionally along microtubules, The founding member of this still growing superfamily is conventional kinesin, a dimeric motor that moves processively ...
Hackney D.D. +5 more
core +1 more source
The kinesin Eg5 inhibitor K858 induces apoptosis but also survivin-related chemoresistance in breast cancer cells [PDF]
, 2016 Inhibitors of kinesin spindle protein Eg5 are characterized by pronounced antitumor activity. Our group has recently synthesized and screened a library of 1,3,4-thiadiazoline analogues with the pharmacophoric structure of K858, an Eg5 inhibitor.
CARRADORI, Simone +8 more
core +1 more source
PLoS Pathogens, 2019 Kinesin-8 proteins are microtubule motors that are often involved in regulation of mitotic spindle length and chromosome alignment. They move towards the plus ends of spindle microtubules and regulate the dynamics of these ends due, at least in some ...
Mohammad Zeeshan +17 more
doaj +1 more source
BMC Plant Biology, 2021 Background Kinesin (KIN) as a motor protein is a versatile nano-machine and involved in diverse essential processes in plant growth and development. However, the kinesin gene family has not been identified in watermelon, a valued and nutritious fruit ...
Shujuan Tian +7 more
doaj +1 more source