Results 171 to 180 of about 23,162 (298)
The NLS3 Motif in TPX2 Regulates Spindle Architecture in Xenopus Egg Extracts
Cytoskeleton, Volume 83, Issue 1, Page 29-39, January 2026.ABSTRACT A bipolar spindle composed of microtubules and many associated proteins functions to segregate chromosomes during cell division in all eukaryotes, yet both spindle size and architecture vary dramatically across different species and cell types.
Guadalupe E. Pena +4 more
wiley +1 more source
The Kinesin-14 Tail: Dual microtubule binding domains drive spindle morphogenesis through tight microtubule cross-linking and robust sliding [PDF]
Stephanie C. Ems-McClung +3 more
openalex +1 more source
TTBK2‐Driven Ciliogenesis Is Required for Intrinsic Neuronal Regeneration After Spinal Cord Injury
CNS Neuroscience &Therapeutics, Volume 32, Issue 1, January 2026.TTBK2‐dependent ciliogenesis is required for intrinsic neuronal regeneration after spinal cord injury. Loss of TTBK2 disrupts primary cilium integrity, attenuates SHH signaling, and impairs axonal regrowth. Restoring SHH activity partially rescues neuronal structural deficits, highlighting the TTBK2/cilium–SHH as a therapeutic target.
Renfeng Zhang +6 more
wiley +1 more source
JIMD Reports, Volume 67, Issue 1, January 2026.ABSTRACT Cell trafficking disorders(CTDs) are rare, heterogeneous inherited conditions marked by impaired intracellular transport mechanisms such as vesicular trafficking, cytoskeletal dynamics, and organelle interactions. Although clinical awareness is increasing, CTDs are often underdiagnosed due to phenotypic overlap with mitochondrial, lysosomal ...
Merve Yoldaş Çelik +6 more
wiley +1 more source
Microfluidic Device to Measure Collective Force Dynamics of Kinesin Motor Proteins [PDF]
, 2018 Joseph M. Cleary, William O. Hancock
openalex +1 more source
The Kaohsiung Journal of Medical Sciences, Volume 42, Issue 1, January 2026.ABSTRACT Ferroptosis resistance is a key player in cervical cancer (CC) development. Hypoxia is a negative factor affecting CC treatment by inducing ferroptosis resistance. Our study aimed to investigate the detailed mechanisms of hypoxia‐induced ferroptosis resistance in CC cells.
Yan Gao, Ting Zou
wiley +1 more source
Molecular Genetics &Genomic Medicine, Volume 14, Issue 1, January 2026.The study identified a novel SEMA3A exons 6–9 deletion variant in Kallmann syndrome that impairs GnRH neuronal migration and alters cell migration, gonad development, and synaptic pathways. The study expands mutation spectrum and offers mechanistic insights for clinical diagnosis of Kallmann syndrome.
Shaolian Zang +4 more
wiley +1 more source