Results 161 to 170 of about 25,177 (273)

Pathways of Protein Secretion in Prokaryotes and Eukaryotes: Molecular Mechanisms, Biological Functions, and Therapeutic Opportunities

open access: yesMedComm, Volume 7, Issue 6, June 2026.
This graphical abstract delineates noncanonical protein secretion systems across eukaryotes and prokaryotes. Eukaryotic UcPS covers four ER–Golgi bypass pathways, enabling rapid leaderless protein export via direct transmembrane translocation or vesicle‐mediated release.
Qiyuan Yang   +8 more
wiley   +1 more source

Tau Differentially Regulates Kinesin-1, Kinesin-2, and Kinesin-3 [PDF]

open access: yesBiophysical Journal, 2019
Dominique V. Lessard   +1 more
openaire   +1 more source

Involvement of kinesins in skeletal dysplasia: a review [PDF]

open access: yes
Skeletal dysplasias are group of rare genetic diseases resulting from mutations in genes encoding structural proteins of the cartilage extracellular matrix (ECM), signaling molecules, transcription factors, epigenetic modifiers, and several intracellular
Bouchenafa R   +2 more
core  

Encephalopathy: Cause, Pathogenesis, and Treatment

open access: yesMedComm, Volume 7, Issue 6, June 2026.
Various encephalopathies (sepsis‐associated, hepatic, hypoxic–ischemic, diabetic, uremic, toxic) have incompletely elucidated pathogenesis, which severely restricts targeted therapy development. Small molecule drugs show unique multitarget potential but face toxicity, poor blood–brain barrier penetration and unclear specificity.
Shimeng Lv   +7 more
wiley   +1 more source

Construction of artificial cilia from microtubules and kinesins through a well-designed bottom-up approach

open access: yes, 2018
Artificial cilia have been fabricated from reconstructed microtubules and kinesins through a well-designed bottom-up approach of self-assembly.
Kazuki Sada   +7 more
core   +1 more source

The Tumor Immune Microenvironment in Endometrial Cancer: Composition, Molecular Subtypes, and Therapeutic Implications

open access: yesMedComm – Oncology, Volume 5, Issue 2, June 2026.
Endometrial cancer (EC), a major gynecologic malignancy and a representative “cold tumor”, exhibits a tumor immune microenvironment (TIME) influenced by a broad range of cellular and molecular elements, immunosuppressive signals, and pathways of immune evasion.
Jingxuan Ye   +4 more
wiley   +1 more source

Not just a pretty cargo carrier: The other face of kinesins

open access: yes, 2018
© 2018 Biochemical Society. If you've only ever heard of one kinesin, it's likely to be one that walks along microtubules and carries cargo around in the cell. However, this type of kinesin is only part of the kinesin story.
Friel, Claire
core   +1 more source

Physicochemical Properties and Mechanisms of Oil‐In‐Water Emulsion Formation and Stabilization by Yeast Protein Ingredients From Saccharomyces cerevisiae and Candida utilis

open access: yesSustainable Food Proteins, Volume 4, Issue 2, June 2026.
Emulsion formation is associated with the soluble phase, while the presence of yeast cells enhances stability through a steric mechanism, with a protein‐to‐oil ratio greater than 1:10 required to prevent oil droplet coalescence. ABSTRACT This study explored the nutrient composition, protein profile, physicochemical and emulsifying properties of ...
Luca Amagliani   +8 more
wiley   +1 more source

The Recycling Endosomal (Na+, K+)/H+ Exchanger NHE6/SLC9A6 Facilitates Signal Transduction by Shuttling Cyclin‐Dependent Kinase 5 to the Plasma Membrane

open access: yesActa Physiologica, Volume 242, Issue 6, June 2026.
ABSTRACT Aim The alkali cation/proton exchanger NHE6/SLC9A6 regulates luminal pH homeostasis and trafficking of recycling endosomes in most tissues, especially neurons. Loss‐of‐function mutations in NHE6 cause Christianson Syndrome, an X‐linked neurodevelopmental and neurodegenerative disorder; however, the underlying molecular and cellular mechanisms ...
Rebecca Flessner   +6 more
wiley   +1 more source

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