Results 101 to 110 of about 91,169 (280)
Plk1 bound to Bub1 contributes to spindle assembly checkpoint activity during mitosis
Scientific Reports, 2017 For faithful chromosome segregation, the formation of stable kinetochore–microtubule attachment and its monitoring by the spindle assembly checkpoint (SAC) are coordinately regulated by mechanisms that are currently ill-defined.
Masanori Ikeda, Kozo Tanaka
doaj +1 more source
The Ndc80 kinetochore complex directly modulates microtubule dynamics [PDF]
, 2012 Neil T. Umbreit +6 more
openalex +1 more source
JEADV Clinical Practice, EarlyView.ABSTRACT Multiple myeloma (MM) is a malignant plasma cell disorder that primarily presents with CRAB symptoms (calcium elevation, renal failure, anemia, and bone abnormalities). In rare cases, MM manifests with systemic complications like skin ulcers, which present management challenges. Here, we report a 78‐year‐old Japanese man with MM and refractory
Naoko Hattori +5 more
wiley +1 more source
Spatial Regulation of Kinetochore Microtubule Attachments by Destabilization at Spindle Poles in Meiosis I [PDF]
, 2015 Lukáš Chmátal +3 more
openalex +1 more source
A Framework for Bioinformatic Reporting in Prenatal Sequencing: Insights From a Systematic Review
Prenatal Diagnosis, EarlyView.ABSTRACT Genomic sequencing has become a key tool in the investigation of foetal anomalies, with a growing shift from targeted panels to exome and genome sequencing. These broader approaches generate significantly more data, underscoring the need for robust bioinformatics pipelines. However, practices vary widely between laboratories.
Ashley J. Pritchard +6 more
wiley +1 more source
On the possibility of yet a third kinetochore system in the protist phylum Euglenozoa
mBioTransmission of genetic material from one generation to the next is a fundamental feature of all living cells. In eukaryotes, a macromolecular complex called the kinetochore plays crucial roles during chromosome segregation by linking chromosomes to ...
Corinna Benz +6 more
doaj +1 more source
PLANTS, PEOPLE, PLANET, EarlyView.Biodiversity is threatened by human activities, with extinction debt accumulating rapidly. Many of these activities change the connectivity of populations, fragmenting existing population systems or bringing previously isolated populations or species into contact.
Zhiqin Long +7 more
wiley +1 more source
Spindle and kinetochore-associated complex subunit 3 (SKA3) promotes stem cell-like properties of hepatocellular carcinoma cells through activating Notch signaling pathway [PDF]
, 2021 Shuya Bai +8 more
openalex +1 more source
Small Methods, EarlyView.This study presents a novel, clinically feasible HER2 testing method using a fully automated digital real‐time PCR platform. It enables real‐time absolute quantification of ERBB2 copy number alterations for rapid, simple, and accurate assessment of HEgR2 status, thereby overcoming the limitations of conventional testing and improving prediction of anti‐
Hee‐Joo Choi +29 more
wiley +1 more source