, 2014 Before a cell divides into two daughter cells, chromosomes are replicated resulting in two sister chromosomes embracing each other. Each sister chromosome is bound to a separate proteinous structure, called kinetochore (kt), that captures the tip of a ...
Chowdhury, Debashish +2 more
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Tubulin interaction with kinetochore proteins: analysis by in vitro assembly and chemical cross-linking. [PDF]
, 1987 R. Balczon, B. R. Brinkley
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Plk1 bound to Bub1 contributes to spindle assembly checkpoint activity during mitosis
Scientific Reports, 2017 For faithful chromosome segregation, the formation of stable kinetochore–microtubule attachment and its monitoring by the spindle assembly checkpoint (SAC) are coordinately regulated by mechanisms that are currently ill-defined.
Masanori Ikeda, Kozo Tanaka
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Cyclin-like accumulation and loss of the putative kinetochore motor CENP-E results from coupling continuous synthesis with specific degradation at the end of mitosis. [PDF]
, 1994 Kevin D. Brown +3 more
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Augmin-dependent microtubule self-organization drives kinetochore fiber maturation in mammals
Cell Reports, 2022 Summary: Chromosome segregation in mammals relies on the maturation of a thick bundle of kinetochore-attached microtubules known as k-fiber. How k-fibers mature from initial kinetochore microtubule attachments remains a fundamental question. By combining
Ana C. Almeida +9 more
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Chromosome motion during attachment to the vertebrate spindle: initial saltatory-like behavior of chromosomes and quantitative analysis of force production by nascent kinetochore fibers. [PDF]
, 1991 Stephanie Alexander, C L Rieder
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Microinjection of biotin-tubulin into anaphase cells induces transient elongation of kinetochore microtubules and reversal of chromosome-to-pole motion. [PDF]
, 1992 Eric A. Shelden, Patricia Wadsworth
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Chromatin containing CENP-A and α-satellite DNA is a major component of the inner kinetochore plate [PDF]
, 1997 Omid Vafa, Kevin F. Sullivan
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A putative protein complex consisting of Ctf19, Mcm21, and Okp1 represents a missing link in the budding yeast kinetochore [PDF]
, 1999 J. Ortiz +3 more
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