Results 161 to 170 of about 105,405 (279)
Dynamic crotonylation of Bub3 regulates mitotic checkpoint silencing and chromosome segregation. [PDF]
Shi X +9 more
europepmc +1 more source
ABSTRACT Background Cutaneous monoclonal gammopathy of clinical significance (MGCS) is rare and may present with scleredema‐like fibrosing skin disease. Case A 59‐year‐old man developed progressive induration of the upper body. Laboratory studies revealed an IgG/κ monoclonal protein, and skin biopsy showed dermal thickening with mucin deposition.
Davide Marcolongo +9 more
wiley +1 more source
The Homeobox Genes: Classification, Regulation, Biological Functions, and Diseases
Overview of the homeobox gene superfamily and its pathophysiological roles. The homeobox superfamily comprises several major classes, including ANTP, PRD, TALE, LIM, POU, and others. Among these, the HOX clusters (A–D) play critical roles in embryonic development specifically in conferring cellular identity, regulating morphogenesis, and guiding axial ...
Maedeh Dadzadi +5 more
wiley +1 more source
Liquid–Liquid Phase Separation in Viral Infection and Immunology
LLPS organizes viral replication and antiviral immunity. Viruses hijack LLPS to form replication factories and evade immune sensors, while hosts assemble LLPS‐driven signaling hubs (e.g., MAVS, RIG‐I, and SGs) to amplify interferon responses. Targeting these condensate interfaces offers novel therapeutic strategies against infectious diseases ...
Jiuzhi Xu +5 more
wiley +1 more source
Defining the chromatin-associated protein landscapes on <i>Trypanosoma brucei</i> repetitive elements using synthetic TALE proteins. [PDF]
Carloni R +7 more
europepmc +1 more source
Abstract Shwachman‐Diamond syndrome (SDS) is a rare genetic disorder characterized by pancreatic insufficiency and neutropenia. While most cases are linked to mutations in the SBDS gene, some involve mutations in the GTPase EFL1. This protein works with SBDS to release the anti‐association factor eIF6 from the 60S ribosomal subunit during ribosome ...
Jonathan A. Zúñiga‐Domínguez +6 more
wiley +1 more source
Bayesian data driven modelling of kinetochore dynamics: Space-time organisation of the human metaphase plate. [PDF]
Koki C +5 more
europepmc +1 more source

