Results 161 to 170 of about 44,237 (280)

PSMD14/E2F1 Axis‐Mediated CENPF Promotes the Metastasis of Triple‐Negative Breast Cancer Through Inhibiting Ferroptosis

open access: yesCancer Science, Volume 116, Issue 8, Page 2281-2295, August 2025.
PSMD14/E2F1 axis‐mediated CENPF could promote the metastasis of BC through inhibiting arachidonic acid metabolism‐induced ferroptosis. This research might bring novel insights on discovering methods in alleviating tumor metastasis in BC. ABSTRACT The metastasis of triple‐negative breast cancer (TNBC) usually contributes to the failure of treatment ...
Meifeng Zhou   +4 more
wiley   +1 more source

KLHL5 Contributes to Colorectal Cancer Cell Survival by Promoting Cell Cycle Progression and Suppressing Apoptotic Cell Death

open access: yesCancer Science, EarlyView.
Bioinformatic analysis of 42 KLHL family genes identified KLHL5 as a potential prognostic biomarker for colorectal cancer (CRC), with higher expression in the common molecular subtype (CMS) 4 CRC, which is characterized by poorer overall and recurrence‐free survival rates compared to other CMS groups. KLHL5 immunohistochemical analysis was performed on
Kyosuke Habu   +15 more
wiley   +1 more source

Genetic Profiling Reveals the Distinctions Among MTX‐Associated DLBCL, EBV‐Positive Mucocutaneous Ulcer, and EBV + DLBCL

open access: yesCancer Science, Volume 116, Issue 8, Page 2306-2316, August 2025.
EBV‐ MTX‐DLBCL shows higher driver gene mutation rates and worse outcomes after MTX discontinuation compared to EBV+ MTX‐DLBCL. IDD‐LPDs have lower mutation rates in genes related to clonal hematopoiesis (TET2/DNMT3A) and immune evasion (CD58) compared to EBV + DLBCL. ABSTRACT The WHO recently changed the outline of immunodeficiency/dysregulation (IDD)‐
Takumi Takahashi   +12 more
wiley   +1 more source

Nucleolar Organization in Response to Transcriptional Stress

open access: yesCancer Science, EarlyView.
In this review, we provide an overview of the research field on nucleolar regulation, mainly focusing on nucleolar organization under transcriptional stress. We also highlight the importance of ribosomal DNA stability, particularly in disease prevention, including cancer.
Rikiya Imamura, Takaaki Yasuhara
wiley   +1 more source

Centromeres in the thermotolerant yeast K. marxianus mediate attachment to a single microtubule. [PDF]

open access: yesChromosome Res
Barrero DJ   +6 more
europepmc   +1 more source

Six New Cases of 22q13.2 Gain Including TFC20: First Report of Triplication and Smallest Duplication Associated With Neurodevelopmental Delays

open access: yesClinical Genetics, EarlyView.
This study reports six new cases of 22q13.2 duplication and triplication, including the TCF20 gene, associated with neurodevelopmental disorders and various morphological and systemic abnormalities. The findings suggest a variable expressivity, but their complete penetrance remains uncertain compared to well‐established loss‐of‐function variants ...
Etienne Bizot   +13 more
wiley   +1 more source

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