Results 181 to 190 of about 117,673 (373)
Small Methods, EarlyView.This study presents a novel, clinically feasible HER2 testing method using a fully automated digital real‐time PCR platform. It enables real‐time absolute quantification of ERBB2 copy number alterations for rapid, simple, and accurate assessment of HEgR2 status, thereby overcoming the limitations of conventional testing and improving prediction of anti‐
Hee‐Joo Choi +29 more
wiley +1 more source
The Mps1 Kinase Modulates the Recruitment and Activity of Cnn1CENP-T at Saccharomyces cerevisiae Kinetochores [PDF]
, 2015 Kriti S. Thapa +4 more
openalex +1 more source
Small Structures, EarlyView.This article highlights the fibrous morphology of multiwalled carbon nanotubes as a key factor in their genotoxicity. Fibers physically interfere in cell division, generating binucleated cells and micronuclei, both of which are precursors of carcinogenesis.
Núria Pulido‐Artola +4 more
wiley +1 more source
Identification of Spindle and Kinetochore-Associated Family Genes as Therapeutic Targets and Prognostic Biomarkers in Pancreas Ductal Adenocarcinoma Microenvironment [PDF]
, 2020 Yi Liu +4 more
openalex +1 more source
CENP-meta, an essential kinetochore kinesin required for the maintenance of metaphase chromosome alignment in Drosophila. [PDF]
, 2000 CENP-meta has been identified as an essential, kinesin-like motor protein in Drosophila. The 257-kD CENP-meta protein is most similar to the vertebrate kinetochore-associated kinesin-like protein CENP-E, and like CENP-E, is shown to be a component of ...
Cleveland, DW +5 more
core
Plant Species Biology, EarlyView.Upon prolonged waterlogging, a Costus speciosus plant developed bulbils at stem node. Karyotype analysis, nucleolar staining, and anatomical study revealed its triploid status and developmental aspects. Prevalence of tetraploid, abundance, and unique reproductive fecundity of the triploid, indicates its determinant role in coexistence of the multiple ...
Surochita Basu +3 more
wiley +1 more source
Meiosis-specific distal cohesion site decoupled from the kinetochore
Nature CommunicationsPrimary constriction of the M-phase chromosome serves as a marker for the kinetochore position. Underlying this observation is the concept that the kinetochore is spatially linked with the pericentromere where sister-chromatids are cohered. Here, we find
Bo Pan +3 more
doaj +1 more source
On the possibility of yet a third kinetochore system in the protist phylum Euglenozoa
mBioTransmission of genetic material from one generation to the next is a fundamental feature of all living cells. In eukaryotes, a macromolecular complex called the kinetochore plays crucial roles during chromosome segregation by linking chromosomes to ...
Corinna Benz +6 more
doaj +1 more source
Russian wheat aphid: a model for genomic plasticity and a challenge to breeders
Insect Science, EarlyView.Invasive foundress finds suitable habitat and reproduces through pathogenesis. Wingless females produce life offspring quickly, which leads to high population densities. High population densities result in competition, which may induce epigenetic changes and wing development for dispersal.
Astrid Jankielsohn +8 more
wiley +1 more source