Results 191 to 200 of about 105,405 (279)

Mepylome: A Point‐of‐Care Tumor Diagnostic Toolkit for Tumor DNA Methylation and Copy Number Analysis

open access: yesAdvanced Intelligent Systems, Volume 8, Issue 3, March 2026.
DNA methylation and chromosomal copy number profiling have recently become essential for tumor diagnostics. The open‐source tool Mepylome enables this task in clinical routine. It combines several machine learning strategies and allows users to interactively examine respective data through an intuitive graphical interface. Running up to 65 times faster
Jon Brugger   +6 more
wiley   +1 more source

Phylogenetic systematics of Juncaceae

open access: yesAmerican Journal of Botany, Volume 113, Issue 3, March 2026.
Abstract Premise Juncaceae has needed taxonomic revision for some time. Specifically, the genus Juncus s.l. is known to be paraphyletic because five small southern‐hemisphere genera have been shown repeatedly to be nested within it. In 2022, a new classification was proposed, based on phylogenies built from one nuclear and three plastid regions ...
Reed J. Kenny   +2 more
wiley   +1 more source

Transposon Ecology and the Octopus Genome

open access: yesBioEssays, Volume 48, Issue 3, March 2026.
Transposable elements (TEs) are mobile strands of DNA prevalent in octopus genomes. TE activity in the octopus brain might reflect an organism‐beneficial role in cognition; or could be a deleterious byproduct of TE parasitism. Viewing TEs from a genome‐ecology perspective generates novel predictions about differential expression levels across “genomic ...
Stefan Linquist   +5 more
wiley   +1 more source

Morphogen Gradients as Drivers of Mosaicism During Early Human Development

open access: yesBioEssays, Volume 48, Issue 3, March 2026.
We hypothesise that the antero‐posterior (A–P) signalling gradients created by the embryonic and extraembryonic interface during human gastrulation generate overlapping patterns of genomic mosaicism, with possible links to embryonic lethality and lineage‐specific developmental disorders.
Sergio P. Acebrón   +3 more
wiley   +1 more source

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