Results 131 to 140 of about 2,276,672 (229)

Conditional knockout of astrocytic Kir4.1 channels impairs central respiratory drive despite maintaining a subset of Cx26+ astrocytes within the RTN

open access: yesThe FASEB Journal, 2016
Central chemoreception is the mechanism by which the brain regulates breathing in response to changes in tissue CO2/H+. The retrotrapezoid nucleus (RTN) has been identified as a key locus for central respiratory control.
V. Hawkins   +3 more
semanticscholar   +1 more source

Genetic deletion of TREK-1 or TWIK-1/TREK-1 potassium channels does not alter the basic electrophysiological properties of mature hippocampal astrocytes in situ

open access: yesFrontiers in Cellular Neuroscience, 2016
We have recently shown that a linear current-to-voltage (I-V) relationship of membrane conductance (passive conductance) reflects the intrinsic property of K+ channels in mature astrocytes. While passive conductance is known to underpin a highly negative
Yixing eDu   +13 more
doaj   +1 more source

Retinitis pigmentosa-associated cystoid macular oedema: pathogenesis and avenues of intervention [PDF]

open access: yes, 2016
Hereditary retinal diseases are now the leading cause of blindness certification in the working age population (age 16-64 years) in England and Wales, of which retinitis pigmentosa (RP) is the most common disorder.
Liew, G, Michaelides, M, Strong, S
core   +1 more source

Update on the implication of potassium channels in autism: K+ channelautism spectrum disorder

open access: yesFrontiers in Cellular Neuroscience, 2015
Autism spectrum disorders (ASDs) are characterized by impaired ability to properly implement environmental stimuli that are essential to achieve a state of social and cultural exchange.
Luca eGuglielmi   +6 more
doaj   +1 more source

Expressional Analysis of Inwardly Rectifying Kir4.1 Channels in Groggy Rats, a Rat Model of Absence Seizures

open access: yes, 2014
Groggy rats, a rat model of human absence seizures, and Slc:Wistar (control) rats, were used in this study. Cortical and hippocampal EEG were recorded to confirm the seizure incidence in Groggy rats. The expression levels of Kir subunits (i.e.
Y. Harada   +8 more
semanticscholar   +1 more source

Роль астроцитів в підтриманні гомеостазу нервової тканини [PDF]

open access: yes, 2018
Статтю присвячено огляду даних літератури щодо основних функцій астроцитів, які мають значення для нормального функціонування нервової системи. Йдеться про підтримку вмісту калію в позаклітинній рідині, оскільки астроцити виконують роль буфера для ...
Клопоцький, Г.А.   +3 more
core  

Distinct expression/function of potassium and chloride channels contributes to the diverse volume regulation in cortical astrocytes of GFAP/EGFP mice.

open access: yesPLoS ONE, 2012
Recently, we have identified two astrocytic subpopulations in the cortex of GFAP-EGFP mice, in which the astrocytes are visualized by the enhanced green-fluorescent protein (EGFP) under the control of the human glial fibrillary acidic protein (GFAP ...
Jana Benesova   +6 more
doaj   +1 more source

Constraints of FL Motif on the Targeting and Function of Sodium-Bicarbonate Cotransporter 1 [PDF]

open access: yes, 2008
A C-terminal dihydrophobic FL motif plays a vital role in the basolateral targeting of sodium bicarbonate cotransporter 1. To further characterize the role of dihydrophobic FL motif, 1). the FL motif in wild type (PFLS) was reversed to LF (PLFS), 2). the
Ali Shawki   +7 more
core   +1 more source

Voltage-Gated Ion Channels Are Transcriptional Targets of Sox10 during Oligodendrocyte Development

open access: yesCells
The transcription factor Sox10 is an important determinant of oligodendroglial identity and influences oligodendroglial development and characteristics at various stages.
Christian Peters   +7 more
doaj   +1 more source

Role of dystrophin and utrophin for assembly and function of the dystrophin glycoprotein complex in non-muscle tissue [PDF]

open access: yes, 2018
.: The dystrophin glycoprotein complex (DGC) is a multimeric protein assembly associated with either the X-linked cytoskeletal protein dystrophin or its autosomal homologue utrophin. In striated muscle cells, the DGC links the extracellular matrix to the
Fritschy, J., Haenggi, T.
core  

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