Results 181 to 190 of about 7,724 (208)
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118 Identification of KISS1 in the Domestic Cat
Reproduction, Fertility and Development, 2017In the last decade, a substantial dataset has been acquired to demonstrate the critical role of kisspeptins, a family of neuropeptides derived from the KISS1 gene, in the reproduction system of mammalian and non-mammalian species. The KISS1 gene initial product can be cleaved into a 54-amino acid protein, and further degrade from the N-terminus into ...
O. Amelkina +2 more
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Estrogenic regulation of Kiss1 mRNA variants in Hatano rats
General and Comparative Endocrinology, 2013Differences in reproductive endocrinology distinguish Hatano high-avoidance animals (HAA) from low-avoidance animals (LAA). Compared to HAA rats, female LAA rats secrete low levels of basal luteinizing hormone (LH) and a reduced LH surge. To investigate the underlying cause of the differences between the two strains, levels of the following mRNAs were ...
Yasuyuki, Horii +6 more
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Vaccine, 2018
Most studies on immunocastration currently focused on male animals. However, immunization of male animals does not completely inhibit sexual behavior and fertility. This study aimed to compare the immunocastration effect of KISS1 DNA vaccines encoding different lengths of kisspeptins in female rats for effective castration effects on both male and ...
Yanguo Han +11 more
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Most studies on immunocastration currently focused on male animals. However, immunization of male animals does not completely inhibit sexual behavior and fertility. This study aimed to compare the immunocastration effect of KISS1 DNA vaccines encoding different lengths of kisspeptins in female rats for effective castration effects on both male and ...
Yanguo Han +11 more
openaire +2 more sources
KISS1 and Kisspeptins Detection in Cell Lines
KISS1 belongs to the family of metastasis suppressor genes. However, its role is not limited to blocking cancer metastasis. KISS1 and its by-product kisspeptins (KP) are important players in regulating the reproductive axis in different species and have new roles in controlling physiological balance and social behaviors.openaire +2 more sources
The Role of KISS1 in Melanoma Metastasis Suppression
2005Among neoplasms, the severity and relevance of metastasis is perhaps most striking in the case of melanoma where surgical resection would conduce cure if not for the subsequent complications of distant metastatic foci. Compounding this notion are statistics revealing that the number of cases of malignant melanoma have doubled each of the last four ...
John F. Harms, Danny R. Welch
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Epigenetic Regulation of the GnRH and Kiss1 Genes
2016This chapter focuses on epigenetic regulation of the GnRH and Kiss1 genes in the context of neuronal development, puberty onset, and reproductive function. Diverse epigenetic phenomena including the formation of chromatin loops, activation of bivalent domains, maintenance of “stable” histone modifications, and DNA methylation, active demethylation, and
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