Results 121 to 130 of about 1,354,109 (194)

Hypothalamic kisspeptin alleviates myasthenia gravis by regulating Th1/Th17/Treg balance through Inhibition of NF-κB signaling pathway

Journal of Neuroinflammation
Background Myasthenia gravis (MG) is an autoimmune disorder affecting neuromuscular junctions. While neuroendocrine-immune system dysfunction plays a crucial role in the development of autoimmune diseases, its involvement in MG remains largely unexplored.
Dan Lu, Linqi Liu, Wenjun Que, Rui Fan, Pingyang Ke, Jing Dong, Yaoqi Gan, Fei Xiao   +7 more
doaj   +1 more source

Gene Structure of the Kiss1 Receptor-2 () in the Atlantic Halibut: Insights into the Evolution and Regulation of Genes

, 2010
Kisspeptin and its receptor, Kiss1r, play an essential role in the control of the onset of puberty in vertebrates. We characterized the cDNA and genomic DNA encoding Kiss1r in Atlantic halibut (). The 1,146bp open reading frame predicts a 381 amino acid protein with high homology to the Kiss1r-2 of other teleost fish.
Mechaly, Alejandro S., Viñas, Jordi, Murphy, Colleen, Reith, Michael, Piferrer, Francesc   +4 more
openaire   +1 more source

KISS1 and Its G Protein-Coupled Receptor (GPR54) in Cancer Progression and Metastasis

, 2012
Activation of G-protein coupled receptor 54 (GPR54) signaling generated by kisspeptins (endogenous GPR54 ligands encoded by KISS1 gene) has been known to regulate puberty and to suppress cancer metastasis. However, an endogenous GPR54 signaling in cancer
Cho, Sunggook Gook
core  

Monosynaptic GABAergic Projections from a Subset of Suprachiasmatic Nucleus Neuromedin S Neurons Suppress Preoptic Area Kisspeptin Neuron Firing in Female Mice. [PDF]

J Neurosci
Abdulmajeed WI, Neuman PN, Jamieson BB, Thomas SX, Rim Y, Novak AG, Lehman MN, Campbell RE, Piet R.   +8 more
europepmc   +1 more source

Mechanisms Linking Body Weight to Early Puberty in Children. [PDF]

Children (Basel)
Nicolaides NC, Toumba M, Tsishkavets A, Sakhi N, Skordis N.   +4 more
europepmc   +1 more source

Obesity, Oxidative Stress, and Inflammation in Precocious Puberty: Do All Roads Lead to the Hypothalamus? [PDF]

Int J Mol Sci
Bizerea-Moga TO, Chișavu F, Chișavu L, Pitulice L, Moga TV, Bugi MA, Foghiș CF, Isac R, Mărginean O, Balica NC.   +9 more
europepmc   +1 more source

Molecular characterization of circannual interval timing in the preoptic area and anteroventral periventricular nucleus in the Djungarian hamster (Phodopus sungorus). [PDF]

J Neuroendocrinol
Stewart C, Marshall C, Stevenson TJ.
europepmc   +1 more source

Effects of Zearalenone on the Kiss1/GPR54 System and Related Genes Expression in the Hypothalamus and Pituitary Gland of Weaned Gilts. [PDF]

Toxins (Basel)
Yuan Z, Zhou M, Luan Y, Kong L, Yang W, Jiang S.   +5 more
europepmc   +1 more source

The KISS1/KISS1R Axis in Human Placentation: Molecular Mechanisms and Implications for Foetal Growth Restriction and Pre-Eclampsia. [PDF]

Int J Mol Sci
Gyokova E, Hristova-Atanasova E, Dimitrova K.   +2 more
europepmc   +1 more source

Effects of chrysin on Kisspeptin, neurokinin B, and dynorphin neurons and <i>gonadotropin-releasing hormone</i> gene expression in stress-induced rats: An experimental study. [PDF]

Int J Reprod Biomed
Haghighat K, Mahmoudi F, Khazali H.
europepmc   +1 more source