Anteroventral Periventricular Kiss1 Gene Expression is Regulated by Estradiol through Estrogen Response Elements [PDF]
In females, estrogen signaling is necessary for coordinating ovulation and the menstrual cycle. KISS1, a gene expressed by kisspeptin neurons and critical for reproduction, is positively and negatively regulated by 17β-estradiol (E2), an endogenous ...
Chou, Teresa
core +1 more source
Abstracts submitted to the ‘EACR 2026 Congress: Innovative Cancer Science’, from 08–11 June 2026 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley +1 more source
Role of amygdala kisspeptin in pubertal timing in female rats.
To investigate the mechanism by which maternal obesity disrupts reproductive function in offspring, we examined Kiss1 expression in the hypothalamic arcuate (ARC) and anteroventral periventricular (AVPV) nuclei, and posterodorsal medial amygdala (MePD ...
Daniel A Adekunbi +9 more
doaj +1 more source
KISS1 gene polymorphisms in Korean girls with central precocious puberty. [PDF]
Kisspeptin/G-protein couple receptor-54 (GPR54) system plays a key role in the activation of the gonadotropic axis at puberty. Central precocious puberty (CPP) is caused by the premature activation of hypothalamic gonadotropin-releasing hormone secretion.
김호성
core +1 more source
KISS1 Metastasis Suppression and Emergent Pathways
Metastatic disease is the most critical impediment to cancer patient survival. However, comparatively little is known concerning the intricate pathways which govern the complex phenotypes associated with metastasis.
Harms, John F. +2 more
core
Effects of prenatal stress on reproductive function of male offspring through the KISS1 system
Prenatal stress can lead to the programming of the neuroendocrine system in male offspring, disrupting the hypothalamic testicular axis and adversely affecting the reproductive health of male offspring. This study aimed to determine the long-term effects
Jian Gong +5 more
doaj +1 more source
A G-rich sequence within the 3'UTR of KiSS1 forms G-quadruplex [PDF]
L’obiettivo dello studio è stato quello di dimostrare che la regione ricca in guanine del 3’UTR del gene KiSS1 forma effettivamente strutture secondarie G-quadruplex e di capire se i polimorfismi trovati nei pazienti affetti da pubertà precoce ...
Bonafè, Giulia
core
Kisspeptin Restores Pulsatile LH Secretion in Patients with Neurokinin B Signaling Deficiencies:Physiological, Pathophysiological and Therapeutic Implications [PDF]
Pulsatile gonadotropin-releasing hormone (GnRH) is crucial to normal reproductive function and abnormalities in pulse frequency give rise to reproductive dysfunction.
Young, Jacques +12 more
core +1 more source
Control of steroid receptor dynamics and function by genomic actions of the cochaperones p23 and Bag-1L [PDF]
Molecular chaperones encompass a group of unrelated proteins that facilitate the correct assembly and disassembly of other macromolecular structures, which they themselves do not remain a part of.
Cato, L. +7 more
core +1 more source
Neurokinin B (NKB) signaling is critical for reproduction in all studied species. The existing consensus is that NKB induces GnRH release via kisspeptin (Kiss1) stimulation in the arcuate nucleus.
Chrysanthi Fergani +5 more
doaj +1 more source

