Results 111 to 120 of about 1,354,109 (194)
Adipose Kiss1 controls aerobic exercise-related adaptive responses in adipose tissue energy homeostasis [PDF]
Kisspeptin signaling regulates energy homeostasis. Adiposity is the principal source and receiver of peripheral Kisspeptin, and adipose Kiss1 metastasis suppressor (Kiss1) gene expression is stimulated by exercise. However, whether the adipose Kiss1 gene
Pan, Xinliang +8 more
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POMC neurons control fertility through differential signaling of MC4R in kisspeptin neurons
eLifeInactivating mutations in the melanocortin 4 receptor (MC4R) gene cause monogenic obesity. Interestingly, female patients also display various degrees of reproductive disorders, in line with the subfertile phenotype of Mc4r KO female mice.
Rajae Talbi +11 more
doaj +1 more source
ERa Signaling in GHRH/Kiss1 Dual-Phenotype Neurons Plays Sex-Specific Roles in Growth and Puberty
, 2020 Gonadal steroids modulate growth hormone (GH) secretion and the pubertal growth spurt via undefined central pathways. GH-releasing hormone (GHRH) neurons express estrogen receptor a (ERa) and androgen receptor (AR), suggesting changing levels of gonadal ...
Elias, Carol, Garcia-Galiano, David
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Reports of Biochemistry and Molecular BiologyInfertility affects about 15% of couples during reproductive age and male factor infertility accounts for half of these cases. This study aimed to evaluate the expression of leptin, KISS1, leptin receptor, and HOTAIR genes in blood and semen samples of individuals diagnosed with oligospermia in comparison to healthy controls.In the current ...
Fatemeh, Khademi +6 more
openaire +2 more sources
eLifeHypothalamic kisspeptin (Kiss1) neurons are vital for pubertal development and reproduction. Arcuate nucleus Kiss1 (Kiss1ARH) neurons are responsible for the pulsatile release of gonadotropin-releasing hormone (GnRH). In females, the behavior of Kiss1ARH
Jian Qiu +8 more
doaj +1 more source
, 2018 Apesar de amplamente estudados, os mecanismos envolvidos no processo de transformação neoplásica das células hipofisárias e na progressão desses tumores permanecem, ainda, pouco esclarecidos.
Amorim, Paulo Vinícius Gonçalves Holanda
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PGR does not regulate Kiss1 gene expression.
, 2016 Kiss1 mRNA expression level in 6-month-old WT (n = 9) and Kiss1-PgrKO (n = 4) mice.
Andrew Wolfe (703417) +9 more
core +1 more source
CRE-dependent PRV-GFP activation in Kiss1 neurons.
, 2019 Stereotaxic delivery of the PRVINTRO virus into the arcuate (ARC) region of mice was associated with GFP expression only in Kiss1-CRE mice. PRVINTRO driven GFP expression (arrowed) at 24 h after delivery was restricted to Kiss1 neurons (A) but at 48 h ...
Clemence Blouet (6519428) +4 more
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KISS1 and Its G Protein-Coupled Receptor (GPR54) in Cancer Progression and Metastasis [PDF]
, 2010 Activation of G-protein coupled receptor 54 (GPR54) signaling generated by kisspeptins (endogenous GPR54 ligands encoded by KISS1 gene) has been known to regulate puberty and to suppress cancer metastasis. However, an endogenous GPR54 signaling in cancer
Cho, Sunggook Gook
core
KISS1 and KISS1R are variably expressed in MSCs, OPCs, and tumor cell lines.
, 2016 Protein expression of the kisspeptin precursor KISS1 and the receptor KISS1R was investigated in primary MSCs (A) and OPCs (B). Specificity of the KISS1R antibody was confirmed by the addition of a blocking antigen (C).
Lorenz C. Hofbauer (759669) +10 more
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