Results 111 to 120 of about 1,110,898 (202)

Proprotein convertases are required for KISS1 processing.

, 2014
A. Amino acid sequence of KISS1 showing three predicted PC cleavage sites − RK, RR and KR in bold. Note: DYKDDDDK at position 68 is the FLAG epitope tag used for several of the studies described in this manuscript. B. Treatment of C8161.9, MelJuSo, HeLa,
Danny R. Welch (160661), Keke M. Pounds (508730), Tomoo Iwakuma (508731), Nabil G. Seidah (148050), Sitaram Harihar (508729)   +4 more
core   +1 more source

Involvement of the kisspeptin system in regulation of sexual behaviors in medaka

iScience
Summary: In mammals, kisspeptin (Kiss1) neurons are generally considered as a sex steroid-dependent key regulator of hypothalamic-pituitary-gonadal (HPG) axis.
Mikoto Nakajo, Shinji Kanda, Yoshitaka Oka   +2 more
doaj   +1 more source

Abstracts from the 2026 Congress of the Scandinavian Society of Anesthesiology and Intensive Care Medicine, Reykjavik, Iceland, June 10–12, 2026

Acta Anaesthesiologica Scandinavica, Volume 70, Issue 9, October 2026.
wiley   +1 more source

Role of Kiss1 in serotonergic modulation in the zebrafish

, 2015
KISS1/Kiss1 gene produces a neuropeptide, kisspeptin with the ability to activate its G-protein coupled receptor, GPR54 (Kiss-R), which is involved in the control of vertebrate reproduction.
Nathan , Fatima Megala
core  

Clinical and Biological Significance of KISS1 Expression in Prostate Cancer [PDF]

, 2012
For men in the United States, prostate cancer (PCa) is the most frequent malignancy and the second leading cause of cancer mortality. The metastatic spread of PCa is responsible for most deaths related to PCa.
Wang, Honghe, Jones, Jacqueline, Hardy, Shana, Grizzle, William E., Yates, Clayton, He, Qinghua P., Turner, Timothy, Welch, Danny R.   +7 more
core   +1 more source

KISS1 and Its G Protein-Coupled Receptor (GPR54) in Cancer Progression and Metastasis [PDF]

, 2010
Activation of G-protein coupled receptor 54 (GPR54) signaling generated by kisspeptins (endogenous GPR54 ligands encoded by KISS1 gene) has been known to regulate puberty and to suppress cancer metastasis. However, an endogenous GPR54 signaling in cancer
Cho, Sunggook Gook
core  

POMC neurons control fertility through differential signaling of MC4R in kisspeptin neurons

eLife
Inactivating mutations in the melanocortin 4 receptor (MC4R) gene cause monogenic obesity. Interestingly, female patients also display various degrees of reproductive disorders, in line with the subfertile phenotype of Mc4r KO female mice.
Rajae Talbi, Todd L Stincic, Kaitlin Ferrari, Choi Ji Hae, Karol Walec, Elizabeth Medve, Achi Gerutshang, Silvia Leon, Elizabeth A McCarthy, Oline K Rønnekleiv, Martin J Kelly, Victor M Navarro   +11 more
doaj   +1 more source

Expression Patterns of Leptin, Leptin Receptor, Kiss1, and HOTAIR Genes in Blood and Semen of Infertile Males with Oligospermia

Reports of Biochemistry and Molecular Biology
Infertility affects about 15% of couples during reproductive age and male factor infertility accounts for half of these cases. This study aimed to evaluate the expression of leptin, KISS1, leptin receptor, and HOTAIR genes in blood and semen samples of individuals diagnosed with oligospermia in comparison to healthy controls.In the current ...
Fatemeh, Khademi, Parimah, Pournaghi, Ali, Vafaei, Kamyab, Hassanpour, Mitra, Bakhiari, Kamran, Mansouri, Bijan, Soleymani   +6 more
openaire   +2 more sources

Kiss1 Metastasis Suppressor Secretion Is Required For Metastasis Suppression [PDF]

, 2006
Failure to reduce the number of cancer deaths over the last 50 years is due to the inability to selectively target metastatic disease. Recently, the KISS1 metastasis suppressor has emerged as a promising molecular agent for the management of metastatic ...
Nash, Kevin T
core  

Adipose Kiss1 controls aerobic exercise-related adaptive responses in adipose tissue energy homeostasis [PDF]

Kisspeptin signaling regulates energy homeostasis. Adiposity is the principal source and receiver of peripheral Kisspeptin, and adipose Kiss1 metastasis suppressor (Kiss1) gene expression is stimulated by exercise. However, whether the adipose Kiss1 gene
Pan, Xinliang, Schmidt, Søren Fisker, Chen, Jianhao, Zhao, Haotian, Sun, Lingyu, Yan, Yi, Liang, Chunyu, Li, Xuehan, Song, Ge   +8 more
core   +1 more source