Kisspeptin Signaling in the Brain [PDF]
Endocrine Reviews, 2009 Abstract Kisspeptin (a product of the Kiss1 gene) and its receptor (GPR54 or Kiss1r) have emerged as key players in the regulation of reproduction. Mutations in humans or genetically targeted deletions in mice of either Kiss1 or Kiss1r cause profound hypogonadotropic hypogonadism.
Donald K Clifton
exaly +5 more sources
Plasma kisspeptin levels are associated with insulin secretion in nondiabetic individuals. [PDF]
PLoS ONE, 2017 To evaluate if plasma kisspeptin concentrations are associated with insulin secretion, as suggested by recent in vitro studies, independently of confounders. 261 nondiabetic subjects were stratified into tertiles according to kisspeptin values.
Francesco Andreozzi +5 more
doaj +5 more sources
Kisspeptin Administration and mRNA Expression in Adult Syrian Hamsters [PDF]
CellsKisspeptin (Kiss1) and kisspeptin 1 receptor (Kiss1R) are vital in regulating various functions across many species, primarily those relating to reproduction.
Megan A. L. Hall +3 more
doaj +2 more sources
Reproductive hormone-dependent and -independent contributions to developmental changes in kisspeptin in GnRH-deficient hypogonadal mice. [PDF]
PLoS ONE, 2010 Kisspeptin is a potent activator of GnRH-induced gonadotropin secretion and is a proposed central regulator of pubertal onset. In mice, there is a neuroanatomical separation of two discrete kisspeptin neuronal populations, which are sexually dimorphic ...
John C Gill +5 more
doaj +5 more sources
Kisspeptin-54 Stimulates the Hypothalamic-Pituitary Gonadal Axis in Human Males [PDF]
Journal of Clinical Endocrinology and Metabolism, 2005 Waljit S Dhillo, Kevin G Murphy
exaly +2 more sources
Postnatal Development of Kisspeptin Neurons in Mouse Hypothalamus; Sexual Dimorphism and Projections to Gonadotropin-Releasing Hormone Neurons [PDF]
Endocrinology, 2006 Jenny Clarkson, Allan E Herbison
exaly +2 more sources
Hypertrophy and Increased Kisspeptin Gene Expression in the Hypothalamic Infundibular Nucleus of Postmenopausal Women and Ovariectomized Monkeys [PDF]
Journal of Clinical Endocrinology and Metabolism, 2007 Adonna Marie Rometo +3 more
exaly +2 more sources
Prolactin-mediates a lactation-induced suppression of arcuate kisspeptin neuronal activity necessary for lactational infertility in mice [PDF]
eLifeThe specific role that prolactin plays in lactational infertility, as distinct from other suckling or metabolic cues, remains unresolved. Here, deletion of the prolactin receptor (Prlr) from forebrain neurons or arcuate kisspeptin neurons resulted in ...
Eleni CR Hackwell +7 more
doaj +2 more sources
VGF changes during the estrous cycle: a novel endocrine role for TLQP peptides? [PDF]
, 2014 Although the VGF derived peptide TLQP-21 stimulates gonadotropin-releasing hormone (GnRH) and gonadotropin secretion, available data on VGF peptides and reproduction are limited.
Brancia C +4 more
core +10 more sources