Conditional kisspeptin neuron-specific Kiss1 knockout with newly generated Kiss1-floxed and Kiss1-Cre mice replicates a hypogonadal phenotype of global Kiss1 knockout mice [PDF]
The Journal of Reproduction and Development, 2020 The present study aimed to evaluate whether novel conditional kisspeptin neuron-specific Kiss1 knockout (KO) mice utilizing the Cre-loxP system could recapitulate the infertility of global Kiss1 KO models, thereby providing further evidence for the ...
Kana IKEGAMI +15 more
doaj +3 more sources
Kisspeptin Administration and mRNA Expression in Adult Syrian Hamsters [PDF]
CellsKisspeptin (Kiss1) and kisspeptin 1 receptor (Kiss1R) are vital in regulating various functions across many species, primarily those relating to reproduction.
Megan A. L. Hall +3 more
doaj +2 more sources
Manipulating seasonality by using PMSG and Kisspeptin hormones and the impact of the MTNR1A gene on reproduction efficiency in ewes. [PDF]
Open Vet JAl-Obaidi MA, Naji IQ, Abd AA.
europepmc +2 more sources
VGF changes during the estrous cycle: a novel endocrine role for TLQP peptides? [PDF]
, 2014 Although the VGF derived peptide TLQP-21 stimulates gonadotropin-releasing hormone (GnRH) and gonadotropin secretion, available data on VGF peptides and reproduction are limited.
Brancia C +4 more
core +10 more sources
Chronic kisspeptin delays puberty and reduces feed intake and body weight in female rats
Journal of Animal Reproduction and Biotechnology, 2021 Kisspeptin is a key player in the central control of reproductive axis. Central administration of kisspeptin has been shown to advance puberty in rats. Stimulation of hypothalamic GnRH pulse generating mechanism by kisspeptin has been proposed to be the ...
Sriravali Sathagopam +3 more
doaj +1 more source
MOLECULAR EVOLUTION OF GPCRS: Kisspeptin/kisspeptin receptors [PDF]
Journal of Molecular Endocrinology, 2014 Following the discovery of kisspeptin (Kiss) and its receptor (GPR54 or KissR) in mammals, phylogenetic studies revealed up to three Kiss and four KissR paralogous genes in other vertebrates. The multiplicity of Kiss and KissR types in vertebrates probably originated from the two rounds of whole-genome duplication (1R and 2R) that occurred in early ...
Pasquier, Jérémy +5 more
openaire +4 more sources
Kisspeptin Regulation of Neuronal Activity throughout the Central Nervous System [PDF]
Endocrinology and Metabolism, 2016 Kisspeptin signaling at the gonadotropin-releasing hormone (GnRH) neuron is now relatively well characterized and established as being critical for the neural control of fertility.
Xinhuai Liu, Allan E. Herbison
doaj +1 more source
Kisspeptin/Kisspeptin Receptor System in the Ovary [PDF]
Frontiers in Endocrinology, 2018 Kisspeptins are a family of neuropeptides that are critical for initiating puberty and regulating ovulation in sexually mature females via the central control of the hypothalamic-pituitary-gonadal axis. Recent studies have shown that kisspeptin and its receptor kisspeptin receptor (KISS1R) are expressed in the mammalian ovary.
Kai-Lun Hu +4 more
openaire +3 more sources
BMC Women's Health, 2023 Highlights 1. Kisspeptin expression is decreased in ovaries of PCOS rat 2. Kisspeptin promotes proliferation and inhibits apoptosis of granulosa cells 3. Kisspeptin alleviates oxidative stress of granulosa cells 4.
Pingping Sun +5 more
doaj +1 more source
Anorexia nervosa and reproduction: connecting brain to gonads [PDF]
, 2020 Anorexia nervosa (AN) is a psychiatric disorder that predominantly affects young women and is characterized by low caloric intake and a major dissatisfaction with one’s body image.
Ciobanu, Corina +3 more
core +2 more sources