Results 21 to 30 of about 16,602 (265)

Correlation of serum kisspeptin levels, ovarian kisspeptin expression, and ovarian BMP15 expression in rat model of polycystic ovarian syndrome

open access: yesOpen Veterinary Journal, 2023
Background: Kisspeptin is a neuropeptide that has an important role in the female reproductive cycle which is indicated by its role in regulating the hypothalamic-pituitary-gonadal axis (HPG axis).
Achmad Rheza   +2 more
doaj   +1 more source

Anorexia nervosa and reproduction: connecting brain to gonads [PDF]

open access: yes, 2020
Anorexia nervosa (AN) is a psychiatric disorder that predominantly affects young women and is characterized by low caloric intake and a major dissatisfaction with one’s body image.
Ciobanu, Corina   +3 more
core   +2 more sources

Kisspeptin Modulation of Reproductive Function

open access: yesEndocrines, 2022
Kisspeptin is a peptide expressed mainly in the infundibular nucleus of the hypothalamus. Kisspeptin plays a crucial role in the regulation of reproductive functions.
Anna Szeliga, Blazej Meczekalski
doaj   +1 more source

Comprehensive Review on Kisspeptin and Its Role in Reproductive Disorders [PDF]

open access: yesEndocrinology and Metabolism, 2015
Kisspeptin has recently emerged as a key regulator of the mammalian reproductive axis. It is known that kisspeptin, acting centrally via the kisspeptin receptor, stimulates secretion of gonadotrophin releasing hormone (GnRH). Loss of kisspeptin signaling
Holly Clarke   +2 more
doaj   +1 more source

MOLECULAR EVOLUTION OF GPCRS: Kisspeptin/kisspeptin receptors [PDF]

open access: yesJournal of Molecular Endocrinology, 2014
Following the discovery of kisspeptin (Kiss) and its receptor (GPR54 or KissR) in mammals, phylogenetic studies revealed up to three Kiss and four KissR paralogous genes in other vertebrates. The multiplicity of Kiss and KissR types in vertebrates probably originated from the two rounds of whole-genome duplication (1R and 2R) that occurred in early ...
Pasquier, Jérémy   +5 more
openaire   +4 more sources

The Correlation between Hormonal Disturbance in PCOS Women and Serum Level of Kisspeptin

open access: yesInternational Journal of Endocrinology, 2020
Background. Kisspeptin is a neuropeptide that upregulates gonadotropin-releasing hormone (GnRH) secretion. It is an essential element for the luteinizing hormone (LH) surge and ovulation.
Razaw O. Ibrahim   +2 more
doaj   +1 more source

Current Perspectives on Kisspeptins Role in Behaviour

open access: yesFrontiers in Endocrinology, 2022
The neuropeptide kisspeptin is now well-established as the master regulator of the mammalian reproductive axis. Beyond the hypothalamus, kisspeptin and its cognate receptor are also extensively distributed in extra-hypothalamic brain regions.
Edouard G. Mills   +6 more
doaj   +1 more source

TGF-β1 inhibits human trophoblast cell invasion by upregulating kisspeptin expression through ERK1/2 but not SMAD signaling pathway

open access: yesReproductive Biology and Endocrinology, 2022
Background Tightly regulation of extravillous cytotrophoblast (EVT) cell invasion is critical for the placentation and establishment of a successful pregnancy.
Lanlan Fang   +7 more
doaj   +1 more source

The Effects of 5-Hydroxytryptamine and Interaction With Kisspeptin in Controlling Ghrelin and Adiponectin Secretion [PDF]

open access: yesInternational Journal of Basic Science in Medicine, 2022
Introduction: 5-Hydroxytryptamine (5HT) and kisspeptin are satiety factors, and ghrelin and adiponectin are orexigenic peptides. In this study, the mediating role of 5HT in the effects of GPR54 receptor blocking on ghrelin and adiponectin secretion was ...
Maryam Kamvar   +4 more
doaj   +1 more source

Investigating the KNDy hypothesis in humans by co-administration of kisspeptin, neurokinin B and naltrexone in men [PDF]

open access: yes, 2016
Context: A subpopulation of hypothalamic neurons co-localise three neuropeptides namely kisspeptin, neurokinin B (NKB) and dynorphin collectively termed KNDy neurons. Animal studies suggest they interact to affect pulsatile GnRH release (KNDy hypothesis);
Abbara, A   +11 more
core   +1 more source

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