Results 31 to 40 of about 21,456 (303)

Kisspeptin and fertility [PDF]

Journal of Endocrinology, 2010
The kisspeptins are a family of peptide hormones, which in recent years have been shown to play a critical role in the regulation of the hypothalamic-pituitary-gonadal axis, thus in turn influencing fertility and reproduction. This review examines the physiological role of kisspeptin and the kisspeptin receptor in the control of gonadotrophin and ...
Saira, Hameed, Channa N, Jayasena, Waljit S, Dhillo   +2 more
openaire   +2 more sources

Correlation of serum kisspeptin levels, ovarian kisspeptin expression, and ovarian BMP15 expression in rat model of polycystic ovarian syndrome

Open Veterinary Journal, 2023
Background: Kisspeptin is a neuropeptide that has an important role in the female reproductive cycle which is indicated by its role in regulating the hypothalamic-pituitary-gonadal axis (HPG axis).
Achmad Rheza, Budi Santoso, Widjiati Widjiati   +2 more
doaj   +1 more source

Anorexia nervosa and reproduction: connecting brain to gonads [PDF]

, 2020
Anorexia nervosa (AN) is a psychiatric disorder that predominantly affects young women and is characterized by low caloric intake and a major dissatisfaction with one’s body image.
Ciobanu, Corina, Fica, Simona, Poterasu, Mihaela, Rowland, David L.   +3 more
core   +2 more sources

Kisspeptin-neuron control of LH pulsatility and ovulation

Frontiers in Endocrinology, 2022
Feedback from oestradiol (E2) plays a critical role in the regulation of major events in the physiological menstrual cycle including the release of gonadotrophins to stimulate follicular growth, and the mid-cycle luteinising hormone (LH) surge that leads
Harvey Stevenson, Samuel Bartram, Mikaela Maria Charalambides, Sruthi Murthy, Theo Petitt, Pradeep A S, Owen Vineall, Ikenna Abaraonye, Amelia Lancaster, K. Koysombat, B. Patel, A. Abbara   +11 more
semanticscholar   +1 more source

Emerging Perspectives on Gonadotropin Regulation in Vertebrates Revealed by the Discovery of FSH-RH in Teleosts. [PDF]

Bioessays
Regarding pituitary gonadotropin regulation, recent studies have shown that in mammals, FSH and LH are regulated by a single GnRH (solo GnRH model), whereas in teleosts, they are regulated by CCK (FSH‐RH) and GnRH (LH‐RH), respectively (dual GnRH model).
Kayo D, Uehara SK, Royan MR, Kanda S.
europepmc   +2 more sources

Kisspeptin Modulation of Reproductive Function

Endocrines, 2022
Kisspeptin is a peptide expressed mainly in the infundibular nucleus of the hypothalamus. Kisspeptin plays a crucial role in the regulation of reproductive functions.
Anna Szeliga, Blazej Meczekalski
doaj   +1 more source

Comprehensive Review on Kisspeptin and Its Role in Reproductive Disorders [PDF]

Endocrinology and Metabolism, 2015
Kisspeptin has recently emerged as a key regulator of the mammalian reproductive axis. It is known that kisspeptin, acting centrally via the kisspeptin receptor, stimulates secretion of gonadotrophin releasing hormone (GnRH). Loss of kisspeptin signaling
Holly Clarke, Waljit S. Dhillo, Channa N. Jayasena   +2 more
doaj   +1 more source

Kisspeptin in the Prediction of Pregnancy Complications

Frontiers in Endocrinology, 2022
Kisspeptin and its receptor are central to reproductive health acting as key regulators of the reproductive endocrine axis in humans. Kisspeptin is most widely recognised as a regulator of gonadotrophin releasing hormone (GnRH) neuronal function. However,
J. Tsoutsouki, B. Patel, A. Comninos, W. Dhillo, A. Abbara   +4 more
semanticscholar   +1 more source

MOLECULAR EVOLUTION OF GPCRS: Kisspeptin/kisspeptin receptors [PDF]

Journal of Molecular Endocrinology, 2014
Following the discovery of kisspeptin (Kiss) and its receptor (GPR54 or KissR) in mammals, phylogenetic studies revealed up to three Kiss and four KissR paralogous genes in other vertebrates. The multiplicity of Kiss and KissR types in vertebrates probably originated from the two rounds of whole-genome duplication (1R and 2R) that occurred in early ...
Pasquier, Jérémy, Kamech, Nédia, Lafont, Anne-Gaelle, Vaudry, Hubert, Rousseau, Karine, Dufour, Sylvie   +5 more
openaire   +4 more sources

Advances in clinical applications of kisspeptin-GnRH pathway in female reproduction

Reproductive Biology and Endocrinology, 2022
Background Kisspeptin is the leading upstream regulator of pulsatile and surge Gonadotrophin-Releasing Hormone secretion (GnRH) in the hypothalamus, which acts as the key governor of the hypothalamic-pituitary-ovary axis.
K. Hu, Zimiao Chen, Xiaoxue Li, Enci Cai, Haiyan Yang, Yi Chen, Congying Wang, Li-Ying Ju, Wenhai Deng, L. Mu   +9 more
semanticscholar   +1 more source