Results 171 to 180 of about 1,992 (211)

Synthesis and characterisation of DOTA-kisspeptin-10 as a potential gallium-68/lutetium-177 pan-tumour radiopharmaceutical. [PDF]

J Neuroendocrinol
Kleynhans J, Reeve R, Driver CHS, Marjanovic-Painter B, Sathekge M, Zeevaart JR, Ebenhan T, Millar RP.   +7 more
europepmc   +1 more source

Atrazine alters kisspeptin signaling and downstream neuroendocrine regulation following embryonic exposure in zebrafish. [PDF]

Toxicology
Stradtman SC, Sathisaran U, Dierolf BK, Sumner G, Tamagno WA, Freeman JL.   +5 more
europepmc   +1 more source

Integrating mechanistic models to decode the GnRH pulse generator in female mice. [PDF]

J Mol Endocrinol
Nechyporenko K, Ivanova D, Li XF, Tsaneva-Atanasova K, Voliotis M, O'Byrne KT.   +5 more
europepmc   +1 more source

Kisspeptin-10 binding to Gpr54 in osteoclasts prevents bone loss by activating Dusp18-mediated dephosphorylation of Src. [PDF]

Nat Commun
Li Z, Yang X, Fu R, Wu Z, Xu S, Jiao J, Qian M, Zhang L, Wu C, Xie T, Yao J, Wu Z, Li W, Ma G, You Y, Chen Y, Zhang HK, Cheng Y, Tang X, Wu P, Lian G, Wei H, Zhao J, Xu J, Ai L, Siwko S, Wang Y, Ding J, Song G, Luo J, Liu M, Xiao J.   +31 more
europepmc   +1 more source

Kisspeptins, Estrogens and Male Fertility [PDF]

Current Medicinal Chemistry, 2016
The control of male fertility requires accurate endocrine, paracrine and autocrine communications along the hypothalamus-pituitary-gonad (HPG) axis. In this respect, the possible interplay between upcoming/classical modulators of reproductive functions deserves attention in that may be a successful tool for the future exploitation of new potential ...
Gilda Cobellis, Vincenza Ciaramella, Riccardo Pierantoni   +2 more
exaly   +5 more sources

Dissecting the KNDy hypothesis: KNDy neuron-derived kisspeptins are dispensable for puberty but essential for preserved female fertility and gonadotropin pulsatility [PDF]

Metabolism: Clinical and Experimental, 2023
peer reviewed[en] BACKGROUND: Kiss1 neurons in the hypothalamic arcuate-nucleus (ARC) play key roles in the control of GnRH pulsatility and fertility. A fraction of ARC Kiss1 neurons, termed KNDy, co-express neurokinin B (NKB; encoded by Tac2). Yet, NKB-
Encarnacion Torres, Silvia Leon, Inmaculada Velasco   +2 more
exaly   +4 more sources

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Timeline: kisspeptins

Lancet Diabetes and Endocrinology,the, 2013
Waljit Dhillo
exaly   +3 more sources

Kisspeptin and Prolactin

Seminars in Reproductive Medicine, 2019
AbstractThe relationship between elevated prolactin and infertility has been known for a long time, but the specific mechanism by which prolactin inhibited reproduction had been uncertain. The discovery of kisspeptin has provided novel insights into how prolactin might cause infertility, with extensive evidence that elevated prolactin inhibits ...
David R, Grattan, Raphael E, Szawka
openaire   +2 more sources

A Role for Kisspeptins in the Regulation of Gonadotropin Secretion in the Mouse

Endocrinology, 2004
Kisspeptins are products of the KiSS-1 gene, which bind to a G protein-coupled receptor known as GPR54. Mutations or targeted disruptions in the GPR54 gene cause hypogonadotropic hypogonadism in humans and mice, suggesting that ...
Jeremy Smith, Donald K Clifton, William F Crowley   +2 more
exaly   +1 more source