Results 41 to 50 of about 886,470 (223)
Technology in Cancer Research & Treatment, 2020 Cancer stem cells, a special subgroup of cancer cells, have self-renewal capabilities and multidirectional potential, which may be reprogrammed from the dedifferentiation of cancer cells, contributing to the failure of clinical treatments.
Mei Chen BSc +4 more
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Kruppel-like factor 4 regulates neutrophil activation
Blood Advances, 2017 : Neutrophils are the most abundant white blood cells in circulation and are key components of the innate immune response. Clinical and experimental studies support an important role for the neutrophils in a broad spectrum of acute and chronic ...
Yuyan Shen +7 more
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Tumor Biology, 2017 Purpose: The aim of this study was to explore the associations of Kruppel-like factor 4 expression with sensitivity to radiation therapy in locally advanced cervical squamous cell carcinoma patients.
Hai-Xia Liu +10 more
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Cell Death and Disease, 2020 Cancer immunotherapy has become a well-established treatment option for some cancers; however, its use is hampered by its cardiovascular adverse effects. Immune checkpoint inhibitors (ICIs)-related cardiac toxicity took place in kinds of different forms,
Wenzheng Xia +4 more
semanticscholar +1 more source
Stress Hematopoiesis Is Regulated by the Krüppel‐Like Transcription Factor ZBP‐89 [PDF]
, 2014 Previous studies have shown that ZBP‐89 (Zfp148) plays a critical role in erythroid lineage development, with its loss at the embryonic stage causing lethal anemia and thrombocytopenia. Its role in adult hematopoiesis has not been described.
Arnaout, M. Amin +5 more
core +1 more source
Elevated Krüppel-like factor 4 transcription factor in canine mammary carcinoma
BMC Veterinary Research, 2011 Background Krüppel-like factors (KLFs) are critical regulators of biological and physiological systems and have been extensively studied for their roles in cell proliferation, differentiation and survival in the context of cancer. Among the KLFs, KLF4 is
Yeh Kun-Tu +5 more
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Krüppel-like factor 15 in liver diseases: Insights into metabolic reprogramming
Frontiers in Pharmacology, 2023 Liver diseases, characterized by metabolic disorder, have become a global public health problem with high morbidity and mortality. Krüppel-like factor 15 (KLF15) is a zinc-finger transcription factor mainly enriched in liver. Increasing evidence suggests
Hao Chen +5 more
doaj +1 more source
Key signalling nodes in mammary gland development and cancer: the snail1-twist1 conspiracy in malignant breast cancer progression [PDF]
, 2010 Breast cancer is the most common cancer among women, and despite significant advances in diagnosing and treating it, metastatic spread of cancer cells results in a high mortality rate. Epithelial-to-mesenchymal transition (EMT) is an embryonic program in
Foubert, Ellen +2 more
core +2 more sources
Eosinophil function in adipose tissue is regulated by Krüppel-like factor 3 (KLF3)
Nature Communications, 2020 The conversion of white adipocytes to thermogenic beige adipocytes represents a potential mechanism to treat obesity and related metabolic disorders.
Alexander J. Knights +13 more
semanticscholar +1 more source
Krüppel-like factor KLF8 plays a critical role in adipocyte differentiation. [PDF]
PLoS ONE, 2012 KLF8 (Krüppel-like factor 8) is a zinc-finger transcription factor known to play an essential role in the regulation of the cell cycle, apoptosis, and differentiation. However, its physiological roles and functions in adipogenesis remain unclear.
Haemi Lee +6 more
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