Results 51 to 60 of about 32,597 (198)

Transcriptional profiling of fetal hypothalamic TRH neurons [PDF]

, 2011
RIGHTS : This article is licensed under the BioMed Central licence at http://www.biomedcentral.com/about/license which is similar to the 'Creative Commons Attribution Licence'.
Castillo-Ramirez, Santiago, Charli, Jean-Louis, Guerra-Crespo, Magdalena, Gutierrez-Rios, Rosa M, Janga, Sarath Chandra, Joseph-Bravo, Patricia, Perez-Martinez, Leonor, Perez-Monter, Carlos   +7 more
core   +4 more sources

Klf15 Is Critical for the Development and Differentiation of Drosophila Nephrocytes [PDF]

, 2015
Insect nephrocytes are highly endocytic scavenger cells that represent the only invertebrate model for the study of human kidney podocytes. Despite their importance, nephrocyte development is largely uncharacterised.
A Halme, AC Crossley, Achim Paululat, AD Alvarez, AJ Vilella, AS Tutor, B Wang, BB McConnell, C Burnett, C Lehmacher, D Das, D Das, D Jeyaraj, D Jeyaraj, D Leiss, DA Kimbrell, EJ Ward, F Grahammer, F Zhang, GG Neely, H Weavers, HY Lim, J Sellin, J Sellin, James H. Catterson, Jessica R. Ivy, JH Catterson, JL Brown, Karen Ocorr, KK Sorensen, LJ Zhu, M Helmstadter, M Togel, Maik Drechsler, P Tomancak, Paul S. Hartley, Q He, Rolf Bodmer, Ruben Artero, S Fisch, S Haralalka, S Zaffran, S Zhuang, SE McGuire, SF Soukup, SK Aggarwal, SK Mallipattu, SK Sasse, VB Wigglesworth, VR Chintapalli, VY Arshavsky, X Gao, Z Han, Z Han   +53 more
core   +15 more sources

Association of serum KLF5 and actinin-4 levels with prognosis of TACE treatment for hepatocellular carcinoma [PDF]

Jichu yixue yu linchuang
Objective To explore the relationship between serum Krüppel-like factor 5(KLF5) and actinin-4 with prognosis of hepatocellular carcinoma (HCC) treated with transcatheter arterial chemoembolization (TACE).
LI Shunle, LI Rong, TIAN Yaya, RAN Xiaoli, ZHAO Yanpei, XU Meng
doaj   +1 more source

A Patient‐Derived Organoid Biobank of Adamantinomatous Craniopharyngioma as a Platform for Drug Discovery

Advanced Science, EarlyView.
This study successfully establishes adamantinomatous craniopharyngioma (ACP) patient‐derived organoids (PDOs) that preserve the histopathological and genetic features of the original tumors. Through drug sensitivity assays and subsequent mechanistic analyses, the study demonstrates that Ceritinib exerts its inhibitory effects on ACP PDO growth by ...
Huarong Zhang, Chaohu Wang, Jun Fan, Zexin Chen, Haoying Yu, Yawen Bai, Tingcheng Zhang, Qianchao Zhu, Yiwen Feng, Peirong Niu, Jiaqian Chen, Liping Yang, Xueying Li, Lei Yu, Songtao Qi, Yi Liu   +15 more
wiley   +1 more source

Untersuchungen zur Rolle des Transkriptionsfaktors "Krueppel-like factor 4" in der Sertoli-Zelle der Maus [PDF]

, 2006
Der Zinkfinger-Transkriptionsfaktor "Krueppel-like factor 4" (Klf4) wird in Epithelzellen vieler Gewebe, wie z.B. des Darms, des Magens und der Haut stark exprimiert.
Godmann, Maren, Renkawitz-Pohl, Renate (Prof. Dr.)   +1 more
core   +1 more source

Plant Virus‐Induced Inheritable Apoptosis Drives Reproductive Costs in Female Insect Vectors to Balance Viral Biparental Transmission

Advanced Science, EarlyView.
Rice gall dwarf virus (RGDV), transmitted biparentally by leafhopper vector to their offspring, exploits the capsid protein to induce inheritable ovarian apoptosis via insulin‐driven PI3K/AKT/FoxO signaling axis. This mechanism enhances infection but reduces female reproductive fitness, causing inefficient maternal transmission.
Haibo Wu, Wenqiang Wan, Qingquan Liang, Hengsong Yang, Chengcong Lu, Taiyun Wei, Qian Chen   +6 more
wiley   +1 more source

Bioinformatic Prediction of Novel microRNAs Encoded in Krüppel-like Factor 4 Gene [PDF]

Journal of Genetic Resources
MicroRNAs are small non-coding RNAs that can regulate gene expression that affects various cellular processes. Krüppel-like factor 4 (KLF4) is a transcription factor that has different regulatory functions, and it plays a role in various cellular ...
Mina Zahiri, Maryam Hassanlou, Amir-Reza Javanmard, Nooshin Bijari   +3 more
doaj   +1 more source

Control of germ-band retraction in Drosophila by the zinc-finger protein HINDSIGHT [PDF]

, 1997
Drosophila embryos lacking hindsight gene function have a normal body plan and undergo normal germ-band extension. However, they fail to retract their germ bands.
Lamka, Michele L., Lipshitz, Howard D., Yip, M. L. Richard   +2 more
core  

TRIM56 Aggravates Cerebral Ischemia‐Reperfusion Injury via Inhibiting KLF4‐Activated Ferroptosis Signaling

Advanced Science, EarlyView.
This study reveals that the E3 ubiquitin ligase TRIM56 exacerbates neuronal ferroptosis and brain damage by mediating K48‐linked ubiquitination and degradation of KLF4, leading to suppression of the xCT/GSH/GPX4 axis. Targeting TRIM56 alleviates cerebral ischemia‐reperfusion injury in vivo and in vitro, highlighting its therapeutic potential.
Qiangping Wang, Shuang Li, Man Li, Wenke Zhou, Jianqing Zhang, Zhenfu Wu, Zhaoqi Mao, Juan Wan, Xinhao Tang, Baoping Zheng, Qiang Liu, Zhendong Li, Xiaobing Jiang, Qingping Wu, Youfan Ye, Haijun Wang   +15 more
wiley   +1 more source

Krüppel‐like factor 4 induces apoptosis and inhibits tumorigenic progression in SK‐BR‐3 breast cancer cells

FEBS Open Bio, 2015
Krüppel‐like factor 4 (KLF4) functions as either a tumor suppressor or an oncogene in different tissues by regulating the expression of various genes.
Bing Wang, Ming-zhi Zhao, Nai-peng Cui, Dan-dan Lin, An-yi Zhang, Yan Qin, Cai-yun Liu, Wei-tao Yan, Jian-hong Shi, Bao-ping Chen   +9 more
doaj   +1 more source