Results 1 to 10 of about 882,731 (192)
Participation of Krüppel-like Factors in Atherogenesis [PDF]
Metabolites, 2023 Atherosclerosis is an important problem in modern medicine, the keys to understanding many aspects of which are still not available to clinicians. Atherosclerosis develops as a result of a complex chain of events in which many cells of the vascular wall ...
Stanislav Kotlyarov, Anna Kotlyarova
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The Involvement of Krüppel-like Factors in Cardiovascular Diseases [PDF]
Life, 2023 Krüppel-like factors (KLFs) are a set of DNA-binding proteins belonging to a family of zinc-finger transcription factors, which have been associated with many biological processes related to the activation or repression of genes, inducing cell growth ...
Michelle G. Santoyo-Suarez +10 more
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The functions and prognostic value of Krüppel‐like factors in breast cancer [PDF]
Cancer Cell International, 2022 Background Krüppel‐like factors (KLFs) are zinc finger proteins which participate in transcriptional gene regulation. Although increasing evidence indicate that KLFs are involved in carcinogenesis and progression, its clinical significance and biological
Ke-Yun Zhu +7 more
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Krüppel-like factors in tumors: Key regulators and therapeutic avenues [PDF]
Frontiers in Oncology, 2023 Krüppel-like factors (KLFs) are a group of DNA-binding transcriptional regulators with multiple essential functions in various cellular processes, including proliferation, migration, inflammation, and angiogenesis.
Yuchen Zhang +10 more
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Krüppel‐like factors family in health and disease [PDF]
MedCommKrüppel‐like factors (KLFs) are a family of basic transcription factors with three conserved Cys2/His2 zinc finger domains located in their C‐terminal regions. It is acknowledged that KLFs exert complicated effects on cell proliferation, differentiation,
Tingwen Xiang +5 more
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JACC: Basic to Translational Science, 2018 Krüppel-like factors (KLFs) are deoxyribonucleic acid–binding transcriptional factors that regulate various pathways that control metabolism and other cellular mechanisms.
Nina M. Pollak, PhD +3 more
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Krüppel-Like Factors in Metabolic Homeostasis and Cardiometabolic Disease [PDF]
Frontiers in Cardiovascular Medicine, 2018 Members of the Krüppel-like factor (KLF) family of transcription factors, which are characterized by the presence of three conserved Cys2/His2 zinc-fingers in their C-terminal domains, control a wide variety of biological processes. In particular, recent
Yumiko Oishi, Ichiro Manabe
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Krüppel-Like Factors in Vascular Inflammation: Mechanistic Insights and Therapeutic Potential [PDF]
Frontiers in Cardiovascular Medicine, 2018 The role of inflammation in vascular disease is well recognized, involving dysregulation of both circulating immune cells as well as the cells of the vessel wall itself.
David R. Sweet +6 more
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Krüppel-like factors in cancer progression: three fingers on the steering wheel. [PDF]
Oncotarget, 2014 Kruppel-like factors (KLFs) comprise a highly conserved family of zinc finger transcription factors, that are involved in a plethora of cellular processes, ranging from proliferation and apoptosis to differentiation, migration and pluripotency.
Limame R +4 more
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Krüppel-like factors: Three fingers in control [PDF]
Human Genomics, 2010 Krüppel-like factors (KLFs), members of the zinc-finger family of transcription factors capable of binding GC-rich sequences, have emerged as critical regulators of important functions all over the body.
Swamynathan Shivalingappa K
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