Results 111 to 120 of about 4,369 (260)

A Systematic Review on the Effects and Implications of Kratom Use on Cardiotoxicity

, 2021
Purpose: Mitragyna speciosa, referred to as kratom, is a plant native to Asia known for its opiate- and psychostimulant-like effects. Kratom use in the US has increased in the last fifteen years.
Demoss, Dustin, Briggs, Jeff, Sankar, Aparna, Saxena, Raina   +3 more
core  

Kratom—Pharmacology, Clinical Implications, and Outlook: A Comprehensive Review

, 2020
Kratom, or Mitragyna, is a tropical plant indigenous to Southeast Asia, with unique pharmacological properties. It is commonly consumed by preparing the leaves into decoction or tea, or by grinding them into a powder.
Alan D. Kaye, Elyse M. Cornett, Steven C. Eastlack   +2 more
core   +1 more source

Pengembangan Metode Isolasi dan Identifikasi Mitragynine dalam Daun Kratom (Mitragyna speciosa)

, 2016
Abstrak Kratom (Mitragina speciosa) merupakan tanaman herbal asal Indonesia. Daun kratom memiliki banyak manfaat sebagai obat herbal seperti obat demam, diare, dan penghilang nyeri.
Elsa, Livia
core  

IDENTIFICATION OF LC-MS/MS AND DOCKING ANALYSIS OF TOPOISOMERASE IIΑ INHIBITION FROM KRATOM LEAVES (MITRAGYNA SPECIOSA) AS POTENTIAL ANTICANCER AGENTS

International Journal of Applied Pharmaceutics
Objective: This study aimed to determine the metabolite content of kratom leaves using LC-MS/MS and their activity to inhibit topoisomerase IIα were predicted using molecular docking.
Puja Adi Priatna, S. Rahmah, R. Widyowati, Sukardiman   +3 more
semanticscholar   +1 more source

The effects of kratom (Mitragyna speciosa) on metabolic syndrome-related parameters: a systematic review and meta-analysis

Frontiers in Pharmacology
Background Mitragyna speciosa Korth. [Rubiaceae] is a tropical plant with opioid-like properties used for its metabolic altering effects, but data on the metabolic effects are lacking.
Ajaree Rayanakorn, Pattarachon Apisitwittaya, Shaun Wen Huey Lee, Kantirat Yaja, Ratchanon Inpan, Mingkwan Na Takuathung, N. Koonrungsesomboon   +6 more
semanticscholar   +1 more source

Optimization of a Green Extraction Technique for Kratom (Ketum) Leaf Extract via Accelerated Solvent Extraction: Phytochemical Profiles, Cytotoxicity, and Antinociceptive Activity.

ACS Pharmacology & Translational Science
Kratom (Mitragyna speciosa Korth.) has gained increasing scientific interest for its potential in pain management and addiction treatment. This study employs a green chemistry approach to optimize the extraction of kratom leaves by using Accelerated ...
Nurul Najwa Rusmadi, T. Karunakaran, Faiqah Ramli, Intan Safinar Ismail, Rameshkumar Santhanam, J. D. Yuvenesan Jagabalan, M. H. Abu Bakar, Azira Muhamad, S. Ramanathan   +8 more
semanticscholar   +1 more source

Controversies in Assessment, Diagnosis, and Treatment of Kratom Use Disorder

Current Psychiatry Reports
We apply the Diagnostic and Statistical Manual of Mental Disorders Fifth Edition (DSM-5) criteria for substance use disorders (SUDs) to the herbal product kratom. Similarities and differences between kratom use disorder (KUD) and other SUDs are explored,
Kirsten E. Smith, David H. Epstein, S. Weiss   +2 more
semanticscholar   +1 more source

Modulatory effects of Kratom extract on the gut microbiota of rats: implications for health

BMC Complementary Medicine and Therapies
Background Kratom (Mitragyna speciosa), a plant native to Southeast Asia, is commonly used as a supplement for fatigue, pain relief, mood enhancement, and euphoria.
Nattaya Thongsepee, Sumet Amonyingcharoen, Pholasit Chamod, Wanwisa Himakhun, Kant Sangpairoj, Pongsakorn Martviset, Pathanin Chantree, Phornphan Sornchuer   +7 more
doaj   +1 more source

The therapeutic potential of kratom [PDF]

Addiction, 2018
Oliver Grundmann, Paula N. Brown, Jack Henningfield, Marc Swogger, Zach Walsh   +4 more
openaire   +2 more sources

Blood glucose response to kratom tea (Mitragyna speciosa Korth.)

BIO Web of Conferences
Background: Kratoms are traditionally used in Borneo to manage diabetes by chewing, smoking, or brewing the leaves as tea. Studying its effects on blood glucose is crucial for validating its therapeutic potential.
Dzul Fadly
semanticscholar   +1 more source