Results 91 to 100 of about 4,369 (260)

Intractable nausea and vomiting in naïve ingestion of kratom for analgesia

International Journal of Emergency Medicine, 2020
Background Kratom is a habit-forming opioid-like substance with an acute toxidrome of various symptoms such as diaphoresis, dizziness, nausea, and vomiting. Chronic users require increasing dosages for the analgesic effects.
Vir Singh, Nadir Mulla, James Link Wilson, Aaron Umansky, Jenny Lee, Trilok Stead, Latha Ganti   +6 more
doaj   +1 more source

Drug-Induced Liver Injury Caused by Kratom Use as an Alternative Pain Treatment Amid an Ongoing Opioid Epidemic

Journal of Investigative Medicine High Impact Case Reports, 2019
Kratom ( Mitragyna speciosa ) is a prevalent medicinal plant used mainly for the stimulant and analgesic properties provided through multiple alkaloid compounds.
Caroline Stokes Osborne MD, Amanda N. Overstreet DO, Don C. Rockey MD, Andrew D. Schreiner MD, MSCR   +3 more
doaj   +1 more source

Deaths in Colorado Attributed to Kratom

New England Journal of Medicine, 2019
Deaths in Colorado Attributed to Kratom Kratom is an herbal drug that at high doses has opioid-like effects, but the potential for fatal overdose is unclear.
Ken, Gershman, Krista, Timm, Meredith, Frank, Laurissa, Lampi, Jonathan, Melamed, Roy, Gerona, Andrew A, Monte   +6 more
openaire   +2 more sources

Tianeptine Misuse, Dependence, and Clinical Management: Three Case Reports and Literature Review

Case Reports in Psychiatry, Volume 2026, Issue 1, 2026.
Tianeptine, an antidepressant approved only in Europe, Asia, and Latin America, is available without regulation in the United States through online vendors and various retail locations. The rise in its misuse has raised public concerns, marked by dramatic dose escalation, rapid tolerance, toxicity, and withdrawal symptoms. Substance use disorder due to
Valeria A. Saldana, Paul H. Earley, David S. Silverstein, Yi-lang Tang, Nikhat Kaura   +4 more
wiley   +1 more source

Hyperpigmentation From Chronic Kratom Use: A Case Report and Review of the Literature

Cureus
Kratom, an opioid substitute derived from the leaves of Mitragyna speciosa, is commonly used for its opioid-like effects in East Asia and is gaining popularity in the United States.
Bryan Tassavor, Chae Young Eun, O. Nikolskaia, Ruth Jobarteh-Williams   +3 more
semanticscholar   +1 more source

Antimicrobial Activity of Actinobacteria Isolated From Kratom (Mitragyna speciosa) Leaves: Secondary Metabolite Profiling and Genome Analysis of Micromonospora chersina NRAIS18

International Journal of Microbiology, Volume 2026, Issue 1, 2026.
Actinobacteria associated with medicinal plants are recognized as prolific sources of novel bioactive compounds. Kratom (Mitragyna speciosa) leaves have been reported to contain a diverse array of secondary metabolites with pharmacological activities, including antibacterial, antioxidant, and anti‐inflammatory effects. In this study, 16 actinobacterial
Nittaya Pitiwittayakul, Nanthavut Niyomvong, Nisachon Tedsree, Somboon Tanasupawat, Esha Saini   +4 more
wiley   +1 more source

A Kratomic Bomb

JACC: Case Reports
[Figure: see text]
Vardhmaan Jain, Michael S. Lloyd
openaire   +2 more sources

An In Vitro Examination of Whether Kratom Extracts Enhance the Cytotoxicity of Low-Dose Doxorubicin against A549 Human Lung Cancer Cells

Molecules
Doxorubicin is an effective chemotherapeutic agent in the treatment of solid hematological and non-hematological carcinoma. However, its long-term usage could result in side effects, such as cardiomyopathy, chronic heart failure, neurotoxicity and cancer
A. Bayu, S. I. Rahmawati, Firmansyah Karim, J. A. Panggabean, Dasilva Primarindu Nuswantari, D. W. Indriani, Peni Ahmadi, Rendi Witular, N. I. Dharmayanti, M. Putra   +9 more
semanticscholar   +1 more source

Pharmacokinetic Interaction of Kratom and Cannabidiol in Male Rats

Pharmaceutics
Kratom and cannabidiol products are used to self-treat a variety of conditions, including anxiety and pain, and to elevate mood. Research into the individual pharmacokinetic properties of commercially available kratom and cannabidiol products has been ...
Erin C. Berthold, Shyam H. Kamble, Siva Rama Raju Kanumuri, Michelle A. Kuntz, Alexandria S. Senetra, Yi-Hua Chiang, Sushobhan Mukhopadhyay, Christopher R. McCurdy, Abhisheak Sharma   +8 more
doaj   +1 more source

Kratom [PDF]

Canadian Medical Association Journal, 2019
Mark, Sanderson, Adrianna, Rowe
openaire   +2 more sources