Coupling Krebs cycle metabolites to signalling in immunity and cancer. [PDF]
Nat Metab, 2019 Ryan DG +6 more
europepmc +2 more sources
Mitochondrial Probe Methyltriphenylphosphonium (TPMP) Inhibits the Krebs Cycle Enzyme 2-Oxoglutarate Dehydrogenase. [PDF]
PLoS ONE, 2016 Methyltriphenylphosphonium (TPMP) salts have been widely used to measure the mitochondrial membrane potential and the triphenylphosphonium (TPP+) moiety has been attached to many bioactive compounds including antioxidants to target them into mitochondria
Moustafa Elkalaf +4 more
doaj +2 more sources
Antioxidants (Basel), 2017 Krebs cycle intermediates (KCIs) are reported to function as energy substrates in mitochondria and to exert antioxidants effects on the brain. The present study was designed to identify which KCIs are effective neuroprotective compounds against oxidative
Sawa K +10 more
europepmc +2 more sources
Krebs cycle rewired for macrophage and dendritic cell effector functions
FEBS Letters, 2017 Luke A J O'neill
exaly +2 more sources
Metabolites, 2021 Very long-chain acyl-CoA dehydrogenase deficiency (VLCADD, OMIM 609575) is associated with energy deficiency and mitochondrial dysfunction and may lead to rhabdomyolysis and cardiomyopathy.
Igor Radzikh +5 more
doaj +1 more source
Instability and invariant measure in the mathematical model for oxidative phosphorylation and ATP synthesis in the cell [PDF]
The Ukrainian Biochemical Journal, 2023 The aim of this work was to analyze the process of oxidative phosphorylation and ATP synthesis in a cell using a mathematical model. The scenario of occurrence of the autoperiodic and chaotic modes depending on the ATP dissipation values was determined ...
V. I. Grytsay
doaj +1 more source
Succinate and succinate dehydrogenase as a «foothold» in the Krebs cycle in critical conditions
Антибиотики и Химиотерапия, 2023 Purpose. Search and presentation of data from experimental and clinical studies reflecting the central role of succinate and succinate dehydrogenase in the regulation of adaptation mechanisms in critical conditions. Material and methods.
Yu. P. Orlov +9 more
doaj +1 more source
Animal Reproduction Science, 2021 An overview of the sperm metabolism is presented; using the stallion as a model we review glycolysis, Krebs Cycle and oxidative phosphorylation, paying special attention to the interactions among them.
F. Peña +5 more
semanticscholar +1 more source
Nobel prize winners in metabolism history and diabetology
Сахарный диабет, 2023 The 20th century was the time of large-scale discoveries and their widespread recognition. Metabolism studies and their role in living organisms deserve special attention.
Y. A. El-Taravi +4 more
doaj +1 more source
The Nobel laureates’ contributions to the study of carbohydrate metabolism and its regulation. A. Harden, H. Euler-Chelpin, C. F. Cori, G. T. Cori, E. Sutherland, L. F. Leloir, H. Krebs, F. Lipmann, P. Mitchell [PDF]
The Ukrainian Biochemical Journal, 2020 Carbohydrate metabolism is a complex and multi-stage process. Many scientists (biochemists, physiologists, chemists) worked on deciphering this process, but only some of them were awarded the Nobel Prize.
R. P. Vynogradova +2 more
doaj +1 more source