Results 11 to 20 of about 4,169 (220)

Expanding TREC and KREC Utility in Primary Immunodeficiency Diseases Diagnosis [PDF]

Frontiers in Immunology, 2020
Primary immunodeficiency diseases (PID) area heterogeneous group of disorders caused by genetic defects of the immune system, which manifest clinically as recurrent infections, autoimmune diseases or malignancies.
Ilya Korsunskiy, Ilya Korsunskiy, Oleg Blyuss, Oleg Blyuss, Oleg Blyuss, Maria Gordukova, Natalia Davydova, Alexey Zaikin, Natalia Zinovieva, Sergey Zimin, Robert Molchanov, Aminat Salpagarova, Alina Eremeeva, Maxim Filipenko, Andrey Prodeus, Anatoliy Korsunskiy, Anatoliy Korsunskiy, Peter Hsu, Peter Hsu, Peter Hsu, Daniel Munblit, Daniel Munblit, Daniel Munblit, Daniel Munblit   +23 more
doaj   +6 more sources

TREC and KREC Levels as a Predictors of Lymphocyte Subpopulations Measured by Flow Cytometry [PDF]

Frontiers in Physiology, 2019
Primary immunodeficiency diseases (PID) is a heterogeneous group of disorders caused by genetic defects of the immune system, which manifests clinically as recurrent infections, autoimmune diseases, or malignancies. Early detection of other PID remains a
Ilya Korsunskiy, Ilya Korsunskiy, Ilya Korsunskiy, Oleg Blyuss, Maria Gordukova, Nataliia Davydova, Nataliia Davydova, Susanna Gordleeva, Robert Molchanov, Alan Asmanov, Dmitrii Peshko, Nataliia Zinovieva, Sergey Zimin, Vladimir Lazarev, Aminat Salpagarova, Maxim Filipenko, Ivan Kozlov, Andrey Prodeus, Andrey Prodeus, Andrey Prodeus, Anatoliy Korsunskiy, Anatoliy Korsunskiy, Peter Hsu, Peter Hsu, Daniel Munblit, Daniel Munblit, Daniel Munblit, Daniel Munblit   +27 more
doaj   +5 more sources

TREC and KREC profiles in patients with inborn errors of immunity

Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics)
TREC/KREC analysis is utilized in neonatal screening for the detection of primary immunodeficiencies caused by genetic defects in proteins essential for T- and B-lymphocyte development.
L. Barycheva, L. I. Bachieva, N. A. Kozmova, L. Khachirova, V. V. Kuznetsova   +4 more
semanticscholar   +3 more sources

Beyond TREC: Pivotal role of tandem TREC/KREC assay in Czech SCID NBS pilot programme [PDF]

Pediatric Allergy and Immunology
Severe combined immunodeficiency (SCID) is a fatal but treatable inborn error of immunity (IEI). Newborn screening (NBS) using T‐cell receptor excision circles (TREC) has been adopted globally, with very few countries incorporating kappa recombination ...
M. Bloomfield, E. Hlavackova, Helena Schneiderova, Marek Turnovec, Lukáš Tichý, Zbyněk Čech, P. Chrastina, Lenka Dvořáková, Karolína Pešková, R. Formánková, P. Říha, M. Vlková, Petr Bejdák, Magdaléna Havlišová, E. Froňková, Tomáš Kalina, V. Bily, Dita Ricna, H. Grombiříková, Petr Sedlacek, Jiří Litzman, T. Freiberger, A. Šedivá, A. Klocperk   +23 more
semanticscholar   +4 more sources

TREC and KREC values in patients with congenital heart defects — neonatal screening data

Аллергология и Иммунология в Педиатрии
Relevance. Children with congenital heart disease (CHD) are at high risk of infectious complications with unfavorable outcomes, which is associated with inadequate immune responses.
L. Yu. Barycheva, L. I. Bachieva, A. A. Puchkov, J. G. Selezneva, N. A. Kozmova   +4 more
doaj   +3 more sources

TREC/KREC Levels in Young COVID-19 Patients

Diagnostics, 2021
COVID-19 patients with acute respiratory distress syndrome (ARDS) have an immune imbalance when systemic inflammation and dysfunction of circulating T and B cells lead to a more severe disease.
Maryam B. Khadzhieva, Ekaterina V. Kalinina, Sergey S. Larin, Daria A. Sviridova, Alesya S. Gracheva, Julia V. Chursinova, Vadim A. Stepanov, Ivan V. Redkin, Lyudmila S. Avdeikina, Alexander G. Rumyantsev, Artem N. Kuzovlev, Lyubov E. Salnikova   +11 more
doaj   +3 more sources

THE ROLE OF TREC AND KREC IN ASSESSING THE IMMUNE STATUS OF NEWBORNS

Eurasian Journal of Applied Biotechnology
Newborn screening, based on the quantitative assessment of T-cell receptor excision circles (TREC) and kappa-deleting recombination excision circles (KREC) in dried blood spots, allows for the early diagnosis of various types of primary ...
N. Sikhayeva, S. Volodchenko, E. Kovzel, M. Kissykova, M. Morenko, K. Shnaider, G. Tortayeva, Ye. Sagandykova   +7 more
semanticscholar   +4 more sources

Levels of TREC and KREC molecules significance determining in peripheral blood for predicting the outcome of COVID-19 disease in the acute period [PDF]

Russian Journal of Immunology, 2023
The disease caused by the highly contagious SARS-CoV-2 virus novel coronavirus infection (COVID-19) had killed more than 6.5 million people at the end of December 2022.
M. A. Saitgalina, Y. Ostankova, N. Arsentieva, Z. Korobova, N. Liubimova, V. A. Kashchenko, A. N. Kulikov, D. E. Pevtsov, O. Stanevich, E. I. Chernykh, A. Totolian   +10 more
semanticscholar   +2 more sources

99P Quantitative indicators of TREC and KREC excision rings in malignant neoplasms [PDF]

ESMO Open, 2023
A. Sultanbaev, S. Musin, K. Menshikov, N. Sultanbaeva, I. Menshikova, A. Fatikhova, M. Sultanbaev, V. Askarov, D. Kudlay   +8 more
semanticscholar   +3 more sources

Five years of combined newborn screening quantifying TREC and KREC in Switzerland.

The Journal of Allergy and Clinical Immunology: In Practice
Maarja Soomann, S. Prader, Susanna Sluka, Camille Boucq, J. Pachlopnik Schmid, J. Trück   +5 more
semanticscholar   +4 more sources