Results 21 to 30 of about 4,018 (199)

Photoinactivation vs repair of photosystem II as target of thermal stress in epipelic and epipsammic microphytobenthos communities. [PDF]

open access: yesPLoS ONE, 2023
Microphytobenthos (MPB) inhabiting intertidal flats are exposed to large and sudden changes in temperature, often simultaneously with exposure to direct sunlight.
Cláudia Bártolo   +2 more
doaj   +2 more sources

TREC and KREC values in patients with congenital heart defects — neonatal screening data

open access: yesАллергология и Иммунология в Педиатрии
Relevance. Children with congenital heart disease (CHD) are at high risk of infectious complications with unfavorable outcomes, which is associated with inadequate immune responses.
L. Yu. Barycheva   +4 more
doaj   +2 more sources

Diagnostic significance of determining TREC and KREC T- and B-cell receptor rearrangement products in patients with inborn immune errors

open access: diamondProceedings of the National Academy of Sciences of Belarus Medical series, 2023
Inborn immunity errors such as primary immunodeficiencies in children represent a significant problem for public health, and it is undeniably important to improve the laboratory diagnosis of this pathology by creating new, effective methods for early ...
Ekaterina Polyakova   +9 more
openalex   +3 more sources

Diagnostic significance of determining products of DNA rearrangments of the T-and-B cell receptor TREC/KREC in common variable immunodeficiency

open access: hybridMedical and Biological Problems of Life Activity
Common variable immunedeficiency (CVID) is a group of diseases that are inborn errors of the immune system and are characterized by impaired production of protective antibodies. The reason is a defect in the T- and B-cells, leading to impaired ability to
Ekaterina Polyakova   +12 more
openalex   +2 more sources

Quantitative indicators of TREC and KREC excision circles in malignancies: a prospective cohort study

open access: goldJournal of Modern Oncology
Background. In oncology, of particular interest is the study of the T-cell receptor excision circles (TREC) and the κ-deletion B-cell receptor excision circles (KREC), which are extrachromosomal DNA structures.
А. В. Султанбаев   +9 more
openalex   +2 more sources

Prospective Study of a Cohort of Russian Nijmegen Breakage Syndrome Patients Demonstrating Predictive Value of Low Kappa-Deleting Recombination Excision Circle (KREC) Numbers and Beneficial Effect of Hematopoietic Stem Cell Transplantation (HSCT) [PDF]

open access: goldFrontiers in Immunology, 2017
BackgroundNijmegen breakage syndrome (NBS) is a combined primary immunodeficiency with DNA repair defect, microcephaly, and other phenotypical features.
Elena Deripapa   +15 more
doaj   +2 more sources

Modified quantitative approach for assessing peripheral blood TREC and KREC levels in immunodeficient patients

open access: yesИнфекция и иммунитет, 2022
Introduction. The immune status is a multifaceted parameter quantitatively and qualitatively analyzing functional activity immune system state in immune organs as well as some non-specific mechanisms of antimicrobial protection. Peripheral blood level of
M. A. Saitgalina   +5 more
doaj   +2 more sources

Investigating the Variation of TREC/KREC in Combined Immunodeficiencies

open access: goldIranian Journal of Allergy, Asthma and Immunology, 2021
T-cell receptor excision circles (TREC)/Kappa-deleting recombination excision circles (KREC) assay has been recently recognized for detecting patients with primary (T- and/or B-cell) immunodeficiency (PID).
Leila Shakerian   +11 more
doaj   +2 more sources

Monitoring of Immune Recovery After Hematopoietic Stem Cell Transplantation in Patients with Aplastic Anemia by Quantitative Determination of TREC and KREC

open access: hybridJournal of Human Immunity
Analysis of T- and B-lymphocyte recovery after hematopoietic stem cell transplantation (HSCT) is important for assessing the positive dynamics of treatment. Flow cytometry is informative enough to monitor immune recovery in the post-transplant period.
Ekaterina Polyakova   +3 more
openalex   +2 more sources

Increased incidence of abnormal TREC/ KREC levels is revealed in virtually healthy individuals over the post-pandemic period

open access: yesМедицинская иммунология
The COVID-19 pandemic has posed an unprecedented challenge to global public health. Poor clinical outcomes in COVID-19 were associated with a pathogenic triad of interrelated mechanisms: immune dysregulation, coagulopathy, and secondary immunodeficiency,
A. Yu. Olkhovskaya   +11 more
doaj   +2 more sources

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