Results 41 to 50 of about 157,775 (261)
Kruppel-like factor 4 suppresses neuroblastoma growth by promoting smooth-muscle differentiation [PDF]
, 2011 Poster Board Number: 2105Neuroblastoma (NB) is an embryonic tumor and possesses a unique propensity to exhibit either a spontaneous regression or an unrestrained growth.
Lau, CST, Ngan, E, Tam, P, Tsoi, LS
core +2 more sources
Stem Cells Translational Medicine, 2019 Pluripotent and tissue‐specific stem cells, such as blood‐forming stem cells, are maintained through a balance of quiescence, self‐renewal, and differentiation.
Chun S. Park +3 more
doaj +2 more sources
Differential expression of Kruppel-like factor 4 in cancers of the breast.
, 2021 Breast cancer affects women at relatively high frequency (1). We mined published microarray datasets (2, 3) to determine in an unbiased fashion and at the systems level genes most differentially expressed in the primary tumors of patients with breast cancer. We report here significant differential expression of the gene encoding Kruppel-like factor 4,
Shahan Mamoor
openalex +3 more sources
Dysregulation of Kruppel-like factor 4 during brain development leads to hydrocephalus in mice [PDF]
Proceedings of the National Academy of Sciences, 2011 Kruppel-like factor 4 (KLF4) is involved in self-renewal of embryonic stem cells and reprogramming of somatic cells to pluripotency. However, its role in lineage-committed stem cells remains largely unknown. Here, we show that KLF4 is expressed in neural stem cells (NSCs) and is down-regulated during neuronal differentiation.
Song Qin +3 more
openalex +3 more sources
Kruppel-like Factor 4 Is a Mediator of Proinflammatory Signaling in Macrophages [PDF]
Journal of Biological Chemistry, 2005 Activation of macrophages is important in chronic inflammatory disease states such as atherosclerosis. Proinflammatory cytokines such as interferon-gamma (IFN-gamma), lipopolysaccharide (LPS), or tumor necrosis factor-alpha can promote macrophage activation.
Mark W. Feinberg +5 more
openalex +4 more sources
Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner. [PDF]
Mol Cell Proteomics, 2021 Vélot L +11 more
europepmc +2 more sources
Molecular basis for modulation of the p53 target selectivity by KLF4 [PDF]
, 2012 The tumour suppressor p53 controls transcription of various genes involved in apoptosis, cell-cycle arrest, DNA repair and metabolism. However, its DNA-recognition specificity is not nearly sufficient to explain binding to specific locations in vivo ...
Brandt, Tobias +4 more
core +12 more sources
Effect of Kruppel-like factor 4 on PTZ-induced acute seizure mice. [PDF]
J Cell Mol MedAbstractKruppel‐like factor 4 (Klf4) is a transcription factor that is involved in neuronal regeneration and the development of glutamatergic systems. However, it is unknown whether Klf4 is involved in acute seizure. To investigate the potential role of Klf4 in pentylenetetrazol (PTZ)‐induced seizure, western blotting, immunofluorescence, behaviour ...
Li B +6 more
europepmc +3 more sources
KLF4 (Kruppel-like factor 4 (gut)) [PDF]
Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2011 Review on KLF4 (Kruppel-like factor 4 (gut)), with data on DNA, on the protein encoded, and where the gene is implicated.
Ghaleb, AM, Yang, VW
openaire +2 more sources
Molecular and Cellular Biology, 2023 Recently, the diverse functions of microRNAs (miRNAs) in brain diseases have been demonstrated. We intended to uncover the functional role of microRNA-130b (miR-130b) in cerebral vasospasm (CVS) following subarachnoid hemorrhage (SAH). SAH was induced by
Zewei Huang +4 more
semanticscholar +1 more source