Results 51 to 60 of about 723,697 (239)
Kruppel-like factor 4 is critical for transcriptional control of cardiac mitochondrial homeostasis [PDF]
Journal of Clinical Investigation, 2015 Mitochondrial homeostasis is critical for tissue health, and mitochondrial dysfunction contributes to numerous diseases, including heart failure. Here, we have shown that the transcription factor Kruppel-like factor 4 (KLF4) governs mitochondrial biogenesis, metabolic function, dynamics, and autophagic clearance.
Ling Lai +18 more
openaire +3 more sources
Frontiers in Immunology, 2023 cDC2s occur abundantly in peripheral tissues and arise from circulating blood cDC2s. However, the factors governing cDC2 differentiation in tissues, especially under inflammatory conditions, remained poorly defined.
Magdalena Lang +8 more
doaj +1 more source
Molecules, 2020 (1) Background: Sesame has been popular as a healthy food since ancient times, and effects of the aroma component of roasted sesame are also expected.
Hiroaki Takemoto +8 more
doaj +1 more source
Prognostic significance of KLF4 in solid tumours: an updated meta-analysis
BMC Cancer, 2022 Background Kruppel-like factor 4 (KLF4) is a zinc finger-containing transcription factor predominantly expressed in terminally differentiated epithelial tissues.
Xiaoya Luo +4 more
doaj +1 more source
Kruppel-like factor 4 attenuates osteoblast formation, function, and cross talk with osteoclasts [PDF]
Journal of Cell Biology, 2014 Osteoblasts not only control bone formation but also support osteoclast differentiation. Here we show the involvement of Kruppel-like factor 4 (KLF4) in the differentiation of osteoclasts and osteoblasts. KLF4 was down-regulated by 1α,25-dihydroxyvitamin D3 (1,25(OH)2D3) in osteoblasts.
Jung Ha Kim +8 more
openaire +3 more sources
Frontiers in Immunology, 2018 Rheumatoid arthritis (RA) is a chronic autoimmune disease that causes mild to severe joint inflammation. During RA pathogenesis, fibroblast-like synoviocytes (FLS) acquire a tumor-like phenotype and mediate cartilage destruction both directly and ...
Seungjin Choi +16 more
doaj +1 more source
Some Results on Factorization of Monoids [PDF]
arXiv, 2022 Factorizations of monoids are studied. Two necessary and sufficient conditions in terms of so-called descent 1-cocyles for a monoid to be factorized through two submonoids are found. A full classification of those factorizations of a monoid whose one factor is a subgroup of the monoid is obtained.
arxiv
Universal factorization spaces and algebras [PDF]
Mathematical Research Letters, Volume 26 (2019), Number 4, 2016 We introduce categories of weak factorization algebras and factorization spaces, and prove that they are equivalent to the categories of ordinary factorization algebras and spaces, respectively. This allows us to define the pullback of a factorization algebra or space by an \'etale morphism of schemes, and hence to define the notion of a universal ...
arxiv +1 more source
$B \to ρ\ell ν_\ell$ Form Factors [PDF]
Phys. Rev. D 54, 6842 (1996), 1996 The bounds on the form factors for $B \to \rho \ell \nu_\ell$ decay are studied. Constrained by lattice data and a constrained conformal mapping, the more informations can be obtained for $A_1(q^2)$ form-factor which dominates the decay rate at large $q^2$. Specifically, we confirm a moderately increasing behavior of this form factor.
arxiv +1 more source
Transplantation Direct, 2018 Background. Steatosis is a major risk factor for primary nonfunction in liver transplantations. Steatotic livers recover poorly from ischemia reperfusion injury, in part due to alterations in the microcirculation, although the exact mechanism is unclear.
Irene Beijert, MD +9 more
doaj +1 more source