Results 81 to 90 of about 723,697 (239)

NMR implementation of Factoring Large Numbers with GaußSums: Suppression of Ghost Factors [PDF]

EPL, 84 (2008) 40006, 2008
Finding the factors of an integer can be achieved by various experimental techniques, based on an algorithm developed by Schleich et al., which uses specific properties of Gau\ss{}sums. Experimental limitations usually require truncation of these series, but if the truncation parameter is too small, it is no longer possible to distinguish between ...
arxiv   +1 more source

β‐Glucuronidase‐Expressing Lactobacillus reuteri Triggers Irinotecan Enterotoxicity Through Depleting the Regenerative Epithelial Stem/Progenitor Pool

Advanced Science, EarlyView.
XLP mitigated CPT11 mucositis by suppressing GUS‐expressing microbes, notably L. reuteri, and diminishing bacterial GUS activity, consequently reducing SN38 accumulation to protect the intestinal epithelium. This preservation of the mucosal stem cell niche enabled rapid regeneration of secretory lineages such as mucin‐producing goblet cells, which ...
Bei Yue, Ruiyang Gao, Ling Zhao, Donghui Liu, Cheng Lv, Ziyi Wang, Fangbin Ai, Beibei Zhang, Zhilun Yu, Xiaolong Geng, Hao Wang, Kang Wang, Kaixian Chen, Chenghai Liu, Zhengtao Wang, Wei Dou   +15 more
wiley   +1 more source

Krüppel-like factor 4 regulates macrophage polarization.

Journal of Clinical Investigation, 2011
Current paradigms suggest that two macrophage subsets, termed M1 and M2, are involved in inflammation and host defense. While the distinct functions of M1 and M2 macrophages have been intensively studied - the former are considered proinflammatory and ...
Xudong Liao, N. Sharma, F. Kapadia, Guangjin Zhou, Yuan Lu, H. Hong, K. Paruchuri, Ganapati H. Mahabeleshwar, E. Dalmas, N. Venteclef, C. Flask, Julian Kim, B. Doreian, K. Lu, K. Kaestner, A. Hamik, K. Clément, M. Jain   +17 more
semanticscholar   +1 more source

Kruppel-like Factor 4 Regulates Laminin α3A Expression in Mammary Epithelial Cells [PDF]

Journal of Biological Chemistry, 2001
Laminin-5, the major extracellular matrix protein produced by mammary epithelial cells, is composed of three chains (designated alpha3A, beta3, and gamma2), each encoded by a separate gene. Laminin-5 is markedly down-regulated in breast cancer cells. Little is known about the regulation of laminin gene transcription in normal breast cells, nor about ...
Marie L. Peddinghaus, Nisha N. Fernandes, Patrick W. Turk, Sigmund A. Weitzman, Elizabeth A. Eklund, Bayar Thimmapaya, Kristi A. Miller, Zhengjin Cao   +7 more
openaire   +3 more sources

KLF1 Promotes Cardiomyocyte Proliferation and Heart Regeneration Through Regulation of Wnt/β‐Catenin Signaling Pathway

Advanced Science, EarlyView.
In KLF1‐on (neonatal and Klf1 overexpression hearts) models, KLF1 regulates Wnt/β‐catenin signaling pathway and the expression of cell proliferation‐related genes via transcriptional and epigenetic mechanisms, which induces cardiomyocyte proliferation and cardiac regeneration in mice after myocardial infarction.
Yanglin Hao, Xi Zhang, Shuan Ran, Yuan Li, Weicong Ye, Song Wang, Xiaohan Li, Zilong Luo, Jiulu Zhao, Junjie Zong, Kexiao Zheng, Ran Li, Han Zhang, Longyong Lai, Pinyan Huang, Zifeng Zou, Wang Zhan, Zhang Yue, Jie Wu, Jiahong Xia   +19 more
wiley   +1 more source

Hydroxamate-Based Histone Deacetylase Inhibitors as Potential Mediators to Induce Dentine Regeneration by Human Dental Pulp Cell

Frontiers in Dental Medicine, 2021
Human dental pulp cells (hDPCs) have shown their plasticity when treated with the hydroxamate-based histone deacetylase (HDAC) inhibitor members, Trichostatin A (TSA), and suberoylanilide hydroxamic acid (SAHA).
Indrani Sulistyowati, Teerawat Sukpaita, Chalida Nakalekha Limjeerajarus, Ruchanee Salingcarnboriboon Ampornaramveth, Ruchanee Salingcarnboriboon Ampornaramveth   +4 more
doaj   +1 more source

Prime Factorization in the Duality Computer [PDF]

, 2006
We give algorithms to factorize large integers in the duality computer. We provide three duality algorithms for factorization based on a naive factorization method, the Shor algorithm in quantum computing, and the Fermat's method in classical computing. All these algorithms are polynomial in the input size.
arxiv   +1 more source

Attenuated Nuclear Tension Regulates Progerin‐Induced Mechanosensitive Nuclear Wrinkling and Chromatin Remodeling

Advanced Science, EarlyView.
The premature aging‐related progerin leads to defective nuclear morphology and is associated with disrupted molecular coupling between the extranuclear cytoskeleton and lamin‐associated nuclear envelope. It is discovered that progerin expression reduces nuclear tension, forms nuclear wrinkling, and enhances chromatin dynamics, thereby regulating ...
Ji‐Eun Park, Juhyeon Jo, Kun Xu, Sun‐Ah Lee, Seong‐Beom Han, YigJi Lee, Won‐Ki Cho, Bo Li, Soo Hyun Kim, Dong‐Hwee Kim   +9 more
wiley   +1 more source

Disentangling Structural Breaks in Factor Models for Macroeconomic Data [PDF]

arXiv, 2023
Through a routine normalization of the factor variance, standard methods for estimating factor models in macroeconomics do not distinguish between breaks of the factor variance and factor loadings. We argue that it is important to distinguish between structural breaks in the factor variance and loadings within factor models commonly employed in ...
arxiv  

PP2A Promotes the Symmetric Division of MUC1‐Dominant Cancer Stem‐Like Cells in Small Cell Lung Cancer

Advanced Science, EarlyView.
During the G2/M phase, mucin1 (MUC1) activates protein phosphatase 2A (PP2A), leading to reduced phosphorylation of protein kinase C ζ (PKCζ) and NUMB, which promotes symmetric division and expansion of cancer stem‐like cells (CSLCs), thereby driving tumorigenesis. Combined inhibition of the MUC1–PP2A axis using LB100/GO203 with etoposide restores PKCζ
Shengze Li, Xinran Dong, Kexing Gao, Yiyang Wang, Min Li, Huayun Deng, Shuangyu Ma, Yaping Lv, Wei Jin, Quanfu Li, Yuming Wang, Xiaodong Liao, Kangjing Bian, Aiwu Zhou, Chengping Hu, Lei Huang   +15 more
wiley   +1 more source