Bioinformatic Prediction of Novel microRNAs Encoded in Krüppel-like Factor 4 Gene [PDF]
Journal of Genetic ResourcesMicroRNAs are small non-coding RNAs that can regulate gene expression that affects various cellular processes. Krüppel-like factor 4 (KLF4) is a transcription factor that has different regulatory functions, and it plays a role in various cellular ...
Mina Zahiri +3 more
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コッカクケイ サイボウ ニ オケル テンシャ インシ Krüppel-Like Factor 4 ノ サヨウ カイセキ [PDF]
Material from: 'Fujikawa, J., Tanaka, M., Itoh, S., et al., Kruppel-like factor 4 expression in osteoblasts represses osteoblast-dependent osteoclast maturation, Cell and Tissue Research, published 2014, Springer ...
フジカワ, ジュンジ +1 more
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Erythroid Kruppel-like factor directly activates the basic Kruppel-like factor gene in erythroid cells [PDF]
, 2007 The Sp/Kriippel-like factor (Sp/KIf) family is comprised of around 25 zinc finger transcription factors that recognize CACCC boxes and GC-rich elements.
Crossley, Merlin +6 more
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MicroRNA-483 amelioration of experimental pulmonary hypertension. [PDF]
, 2020 Endothelial dysfunction is critically involved in the pathogenesis of pulmonary arterial hypertension (PAH) and that exogenously administered microRNA may be of therapeutic benefit.
Bai, Liang +22 more
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Tumor-suppressive role of Kruppel-like factor 4 (KLF-4) in colorectal cancer
Genetics and Molecular Research, 2017 Kruppel-like factors (KLFs) are a group of transcriptional regulators that have recently been identified to exhibit tumor-suppressive function against various gastrointestinal cancers. The present study aims to investigate the expression patterns and prognostic value of KLF-4 in colorectal cancers (CRCs).
D H, Xiu +4 more
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Possible role of Krüppel-like factor 5 in the remodeling of small airways and pulmonary vessels in chronic obstructive pulmonary disease [PDF]
, 2016 BACKGROUND: Small airway remodeling is an important cause of the airflow limitation in chronic obstructive pulmonary disease (COPD). A large population of patients with COPD also have pulmonary hypertension.
Abe, K +14 more
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Kruppel-like factor 4 improves obesity-related nephropathy through increasing mitochondrial biogenesis and activities. [PDF]
J Cell Mol Med, 2020 AbstractObesity is positively linked to multiple metabolic complications including renal diseases. Several studies have demonstrated Kruppel‐like factor 4 (KLF4) participated in renal dysfunction and structural disorders in acute kidney injuries, but whether it affected the process of chronic kidney diseases was unknown. Therefore, present study was to
Jin L +9 more
europepmc +4 more sources
Kruppel-like factor 4 attenuates osteoblast formation, function, and cross talk with osteoclasts [PDF]
Journal of Cell Biology, 2014 Osteoblasts not only control bone formation but also support osteoclast differentiation. Here we show the involvement of Kruppel-like factor 4 (KLF4) in the differentiation of osteoclasts and osteoblasts. KLF4 was down-regulated by 1α,25-dihydroxyvitamin D3 (1,25(OH)2D3) in osteoblasts.
Kim, Jung Ha +8 more
openaire +2 more sources
PACAP neuropeptide promotes Hepatocellular Protection via CREB-KLF4 dependent autophagy in mouse liver Ischemia Reperfusion Injury. [PDF]
, 2020 Organ ischemia reperfusion injury (IRI), associated with acute hepatocyte death, remains an unresolved problem in clinical orthotopic liver transplantation (OLT).
Busuttil, Ronald W +9 more
core
VIP contribution to the decidualization program: regulatory T cell recruitment [PDF]
, 2014 During early pregnancy, the human uterus undergoes profound tissue remodeling characterized by leukocyte invasion and production of proinflammatory cytokines, followed by tissue repair and tolerance maintenance induction.
Agüero, Mariana +5 more
core +1 more source