Results 121 to 130 of about 799,860 (178)

Aging Affects K_V7 Channels and Perivascular Adipose Tissue-Mediated Vascular Tone. [PDF]

Front Physiol, 2021
Wang Y, Yildiz F, Struve A, Kassmann M, Markó L, Köhler MB, Luft FC, Gollasch M, Tsvetkov D.   +8 more
europepmc   +1 more source

SMIT (Sodium-Myo-Inositol Transporter) 1 Regulates Arterial Contractility Through the Modulation of Vascular Kv7 Channels. [PDF]

Arterioscler Thromb Vasc Biol, 2020
Barrese V, Stott JB, Baldwin SN, Mondejar-Parreño G, Greenwood IA.   +4 more
europepmc   +1 more source

Genetic and pharmacological studies of KV7 channels in excitability disorders

The KV7 (KCNQ) subfamily of voltage-gated potassium channels plays a key role in the regulation of neuronal excitability. By controlling the neuronal M-current, KV7 channels represent pharmacological targets for neurological disorders characterized by ...
LUZIO GASPAR, INGRIDE
core  

K_V7 channels are potential regulators of the exercise pressor reflex.

J Neurophysiol, 2021
Wright AB, Sukhanova KY, Elmslie KS.
europepmc   +1 more source

Kcnq (Kv7) channels exhibit frequency-dependent responses via partial inductor-like gating dynamics. [PDF]

Commun Biol
Eguchi Y, Kuwano Y, Okada S, Morino H, Hashimoto K.   +4 more
europepmc   +1 more source

H₂O₂-mediated relaxation in a swine model of ischemic heart disease and exercise training: mechanistic insights and the role of Kv7 channels. [PDF]

Basic Res Cardiol
Self TS, Bray JF, Heaps CL.
europepmc   +1 more source

Cardiovascular Kv7 channels in health and in disease

, 2015
Els canals de potassi dependents de voltatge Kv7.1 i Kv7.5 juguen un paper molt important en la fisiologia del sistema cardiovascular. Aquest canals iònics estan formats per la tetramerització de 4 subunitats α. La heterotetramerizació és un dels mecanisme principals que dona lloc a la immensa diversitat funcional que mostra aquesta família.
openaire   +1 more source

Calcium-sensing receptor regulates Kv7 channels via G_i/o protein signalling and modulates excitability of human induced pluripotent stem cell-derived nociceptive-like neurons. [PDF]

Br J Pharmacol
Chuinsiri N, Siraboriphantakul N, Kendall L, Yarova P, Nile CJ, Song B, Obara I, Durham J, Telezhkin V.   +8 more
europepmc   +1 more source

Discovery of E0199: A novel compound targeting both peripheral Na_V and K_V7 channels to alleviate neuropathic pain. [PDF]

J Pharm Anal
Zhang B, Shi X, Liu X, Liu Y, Li X, Wang Q, Huang D, Zhao W, Cui J, Cao Y, Chai X, Wang J, Zhang Y, Wang X, Jia Q.   +14 more
europepmc   +1 more source

Ca²⁺-Calmodulin and PIP2 interactions at the proximal C-terminus of Kv7 channels. [PDF]

Channels (Austin), 2017
Tobelaim WS, Dvir M, Lebel G, Cui M, Buki T, Peretz A, Marom M, Haitin Y, Logothetis DE, Hirsch JA, Attali B.   +10 more
europepmc   +1 more source