Results 151 to 160 of about 5,018,081 (294)

Gut microbiota modulation accounts for the neuroprotective properties of anthocyanins [PDF]

, 2018
High-fat (HF) diets are thought to disrupt the profile of the gut microbiota in a manner that may contribute to the neuroinflammation and neurobehavioral changes observed in obesity.
A Faria, A Fernandes, A Klindworth, A Sarkar, AG Clooney, AJ Bruce-Keller, AJ Stagg, C Manach, C Marques, C Marques, C Marques, CD Kay, CM Whitfield-Cargile, D Erny, D Wang, ES Ogbonnaya, GB Rogers, H Gowda, HQ Wu, I Solanki, JM Yano, K Gammon, KI Mosher, L Steiner, M Hidalgo, M Meireles, M Meireles, M Meireles, MO Hill, N Castanon, P Bercik, P Brun, P Ho, PD Cani, PJ Kennedy, RM Ransohoff, S Louis, S Salimi Elizei, SM Collins, SM O’Mahony, TG Dinan, WA Banks   +41 more
core   +2 more sources

C-Reactive protein and the kynurenic acid to quinolinic acid ratio are independently associated with white matter integrity in major depressive disorder

Brain, behavior, and immunity, 2022
Haixia Zheng, T. Teague, F. Yeh, Kaiping Burrows, Leandra K. Figueroa-Hall, R. Aupperle, S. Khalsa, M. Paulus, J. Savitz   +8 more
semanticscholar   +1 more source

C–3 alkoxymethylation of 4-oxo-1,4-dihydroquinoline 2-carboxylic acid esters via organic additives

Heliyon
Esters of kynurenic acid, a known neuroprotective agent were reacted with cyclic amino acids to yield novel alkoxymethylated products under optimized reaction conditions.
Péter Simon, Bálint Lőrinczi, István Szatmári   +2 more
doaj  

The intestine and the kidneys : a bad marriage can be hazardous [PDF]

, 2015
The concept that the intestine and chronic kidney disease influence each other, emerged only recently. The problem is multifaceted and bidirectional. On one hand, the composition of the intestinal microbiota impacts uraemic retention solute production ...
Glorieux, Griet, Vanholder, Raymond
core   +1 more source

Sex Differences in Hippocampal Memory and Kynurenic Acid Formation Following Acute Sleep Deprivation in Rats

Scientific Reports, 2018
Inadequate sleep is a prevalent problem within our society that can result in cognitive dysfunction. Elevations in kynurenic acid (KYNA), a metabolite of the kynurenine pathway (KP) of tryptophan degradation known to impact cognition, in the brain may ...
A. Baratta, Silas A. Buck, Austin D. Buchla, Carly B. Fabian, Shuo Chen, J. Mong, Ana Pocivavsek   +6 more
semanticscholar   +1 more source

Kynurenic Acid Protects against Thioacetamide-Induced Liver Injury in Rats

Analytical Cellular Pathology, 2018
Acute liver failure (ALF) is a life-threatening disorder of liver function. Kynurenic acid (KYNA), a tryptophan metabolite formed along the kynurenine metabolic pathway, possesses anti-inflammatory and antioxidant properties. Its presence in food and its
Sebastian Marciniak, Artur Wnorowski, Katarzyna Smolińska, Beata Walczyna, Waldemar Turski, Tomasz Kocki, Piotr Paluszkiewicz, Jolanta Parada-Turska   +7 more
doaj   +1 more source

Activation of nociception‐sensitive ionotropic glutamate receptor‐expressing rostroventrolateral medulla neurons by stimulation of cardiac afferents in rats

FASEB BioAdvances
Myocardial ischemia causes the release of bradykinin, which activates afferent nerve endings in the ventricular epicardium. This elicits a sympathetically mediated increase in arterial pressure and heart rate, referred to as the cardiogenic sympathetic ...
Matthew R. Zahner, Cade C. Oculam, Eric Beaumont   +2 more
doaj   +1 more source

Does the type of exercise affect tryptophan catabolism in horses?

Animal, 2021
Tryptophan (Trp) is an essential amino acid which metabolises via the kynurenine pathway to generate a number of bioactive substances referred to as kynurenines.
W. Kędzierski, I. Sadok, S. Kowalik, I. Janczarek, M. Staniszewska   +4 more
doaj  

Glutamate and opioid antagonists modulate dopamine levels evoked by innately attractive male chemosignals in the nucleus accumbens of female rats [PDF]

, 2017
Sexual chemosignals detected by vomeronasal and olfactory systems mediate intersexual attraction in rodents, and act as a natural reinforcer to them.
Agustín-Pavón, Carmen, Granero Maciá, Luis, Hipólito Cubedo, Lucía, Lanuza Navarro, Enrique, Martínez-García, Fernando, Orrico Sánchez, Alejandro, Polache Vengut, Ana, Sánchez-Catalán, María José, Zornoza Sabina, Teodoro   +8 more
core   +2 more sources

Modulation of striatal quinolinate neurotoxicity by elevation of endogenous brain kynurenic acid [PDF]

, 1998
Crafford A. Harris, Alejandra Miranda, Jeffrey Tanguay, R.J. Boegman, Richard J Beninger, Khem Jhamandas   +5 more
openalex   +1 more source