Results 41 to 50 of about 2,406 (97)

Impact of Substance Use Disorder on Tryptophan Metabolism Through the Kynurenine Pathway: A Narrative Review

Metabolites
Background/Objectives: Substance use disorder is a crisis impacting many people in the United States. This review aimed to identify the effect addictive substances have on the kynurenine pathway.
Lindsey Contella, Christopher L. Farrell, Luigi Boccuto, Alain H. Litwin, Marion L. Snyder   +4 more
doaj   +1 more source

Measurement of kynurenine pathway metabolites by tandem mass spectrometry

Journal of Mass Spectrometry and Advances in the Clinical Lab, 2023
Objectives: Recent studies have shown that derangements in kynurenine pathway metabolite levels are associated with various pathologies such as neurodegenerative diseases, schizophrenia, depression, bipolar disorder, rheumatoid arthritis, and cancer ...
Sedat Abusoglu, Duygu Eryavuz Onmaz, Gulsum Abusoglu, Fatma Humeyra Yerlikaya, Ali Unlu   +4 more
doaj  

Neopterin and Kynurenine in Mesangioproliferative Glomerulonephritis

Pteridines, 1998
Serum kynurenine and neopterin concentrations were determined in patients with chronic mesangioproliferative glomerulonephritis with normal renal function and in patients with chronic renal failure. Significantly increased kynurenine and neopterin levels
Martinsons Agris, Rudzite Vera, Widner Bernhard, Fuchs Dietmar   +3 more
doaj   +1 more source

Inhibition by interferon-gamma of human mononuclear cell-mediated low density lipoprotein oxidation. Participation of tryptophan metabolism along the kynurenine pathway. [PDF]

, 1994
Stephan Christen, S R Thomas, Brett Garner, Roland Stocker   +3 more
openalex   +1 more source

The kynurenine and serotonin pathway, neopterin and biopterin in depressed children and adolescents: an impact of omega-3 fatty acids, and association with markers related to depressive disorder. A randomized, blinded, prospective study

Frontiers in Psychiatry
Depressive disorder is a severe mental condition. In addition to genetic factors, immunological-inflammatory factors, oxidative stress, and disturbances in neurotransmitter metabolism, kynurenine and serotonin pathways may play a role.
Lucia Ilavská, Marcela Morvová, Zuzana Paduchová, Jana Muchová, Iveta Garaiova, Zdenka Ďuračková, Libuša Šikurová, Jana Trebatická   +7 more
doaj   +1 more source

Screening marine natural products for selective inhibitors of key kynurenine pathway enzymes [PDF]

, 2000
Yunjiang Feng, Bruce F. Bowden, Varun Kapoor   +2 more
openalex   +1 more source

NAD Biosynthesis Evolution in Bacteria: Lateral Gene Transfer of Kynurenine Pathway in Xanthomonadales and Flavobacteriales [PDF]

, 2008
Wanessa C Lima, Alessandro M. Varani, Carlos Frederico Martins Menck   +2 more
openalex   +1 more source

Kynurenine pathway metabolism in human blood–brain–barrier cells: implications for immune tolerance & neurotoxicity [PDF]

, 2008
R Owe‐Young, Nicole L. Webster, Muḥammad Mukhtār, Roger J. Pomerantz, George A. Smythe, David W. Walker, Patricia J. Armati, Suzanne M. Crowe, Bruce J. Brew   +8 more
openalex   +1 more source

The Kynurenine Pathway and Indole Pathway in Tryptophan Metabolism Influence Tumor Progression

Cancer Medicine
Tryptophan (Trp), an essential amino acid, is solely acquired through dietary intake. It is vital for protein biosynthesis and acts as a precursor for numerous key bioactive compounds.
Zhanhui Lu, Chengcheng Zhang, Jia Zhang, Wan Su, Guoying Wang, Zhongqi Wang   +5 more
doaj   +1 more source

Genetic and Environmental Impacts in Major Depressive Disorder are Mediated Via Kynurenine Pathway of Tryptophan Metabolism [PDF]

, 2009
Gregory F. Oxenkrug
openalex   +1 more source