Results 11 to 20 of about 31,622 (258)

Characteristics of L-Citrulline Transport across Rat Small Intestine In Vitro [PDF]

Pediatric Research, 1992
The amino acid L-citrulline is an important intermediate of urea cycle and a key precursor for arginine biosynthesis. We have examined the characteristics of citrulline transport across the everted sacs of the rat small intestine. Our studies suggest that the optimal site of citrulline absorption is middle to lower ileum. It shows active transport, and
Jaydutt V. Vadgama, D.F. Evered
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Short-Term L-Citrulline Supplementation Does Not Affect Blood Pressure, Pulse Wave Reflection, or Arterial Stiffness at Rest and during Isometric Exercise in Older Males [PDF]

Sports, 2023
Hypertension and arterial stiffness are significant factors contributing to cardiovascular disease. L-citrulline, a nitric oxide precursor, has been proposed as a nutritional, non-pharmacological blood pressure-lowering intervention.
Andrea Tryfonos, Filippos Christodoulou, George M. Pamboris, Stephanos Christodoulides, Anastasios A. Theodorou   +4 more
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Effects of dietary L-Citrulline supplementation on growth performance, meat quality, and fecal microbial composition in finishing pigs [PDF]

Frontiers in Microbiology, 2023
Gut microbiota play an important role in the gut ecology and development of pigs, which is always regulated by nutrients. This study investigated the effect of L-Citrulline on growth performance, carcass characteristics, and its potential regulatory ...
Junhua Du, Junhua Du, Mailin Gan, Mailin Gan, Zhongwei Xie, Zhongwei Xie, Chengpeng Zhou, Chengpeng Zhou, Yunhong Jing, Yunhong Jing, Menglin Li, Menglin Li, Chengming Liu, Chengming Liu, Meng Wang, Meng Wang, Haodong Dai, Haodong Dai, Zhiyang Huang, Zhiyang Huang, Lei Chen, Lei Chen, Ye Zhao, Ye Zhao, Lili Niu, Lili Niu, Yan Wang, Yan Wang, Shunhua Zhang, Shunhua Zhang, Zongyi Guo, Linyuan Shen, Linyuan Shen, Li Zhu, Li Zhu   +34 more
doaj   +2 more sources

Impact of dietary supplementation of L-citrulline to meat goats during gestation on reproductive performance [PDF]

Journal of Animal Science and Biotechnology
Background Meat goat production is a worldwide industry with products such as meat, milk, soap, and fiber being produced. There are approximately 2.6 million meat goats in the United States.
Makenzie G. Newton, Arianna N. Lopez, Claire Stenhouse, Karina L. Hissen, Erin D. Connolly, Xingchi Li, Lan Zhou, Guoyao Wu, William B. Foxworth, Fuller W. Bazer   +9 more
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NEW METABOLIC PRODUCTS OF L-CITRULLINE AND L-HOMOARGININE [PDF]

Pediatric Research, 1977
Several clinical conditions associated with hyperammonemia are also characterized, in part, by elevated serum and urine levels of citrulline (C), homocitrulline (HC), and homoarginine (HA). Our previous studies on 14C-ureido-HC revealed that HC was converted by rats and mice, and, in vitro, by L-amino acid oxidase to a cyclic derivative (Fed. Proc.
Ronald W. Wilson, Richard Thompson, Arthur F. Kohrman   +2 more
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Palmitic acid-induced cell death: impact of endoplasmic reticulum and oxidative stress, mitigated by L-citrulline [PDF]

Animal Bioscience
Objective Palmitic acid (PA), the most abundant saturated free fatty acids, induces apoptosis in bovine mammary epithelial cells (MECs). It is suggested that oxidative stress and endoplasmic reticulum (ER) stress are key mechanisms underlying PA-induced ...
Md. Rezwanul Habib, Yukako Tokutake, Shinichi Yonekura   +2 more
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Effects of branched chain amino acids, l-citrulline, and alpha-glycerylphosphorylcholine supplementation on exercise performance in trained cyclists: a randomized crossover trial. [PDF]

J Int Soc Sports Nutr, 2023
Harrington RN.
europepmc   +3 more sources

Short-Term L-Citrulline Supplementation Does Not Affect Inspiratory Muscle Oxygenation and Respiratory Performance in Older Adults. [PDF]

Nutrients, 2023
Theodorou AA, Chatzinikolaou PN, Margaritelis NV, Christodoulou F, Tsatalas T, Paschalis V.   +5 more
europepmc   +3 more sources

Potential therapeutic uses of L‐citrulline beyond genetic urea cycle disorders [PDF]

Journal of Inherited Metabolic Disease
AbstractL‐citrulline (referred to hereafter as citrulline), a non‐essential amino acid and an intermediate in the urea cycle, is widely recognized for its role in managing genetic urea cycle disorders (UCDs). Recent studies, however, suggest that citrulline's therapeutic potential extends beyond UCDs, particularly in conditions associated with nitric ...
Marshall Summar
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Oral administration of l-citrulline alters the vascular delivery of substances to rat skeletal muscles

Biochemistry and Biophysics Reports, 2021
Vascular endothelial function deteriorates with age and disease, and the production of vasodilator factors like nitric oxide (NO) decreases. The free amino acid l-citrulline increases vasodilation and blood flow through increased NO production.
Sho Miyatake, Kazuo Hino, Goro Ebisu, Satoshi Fujita   +3 more
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