Results 51 to 60 of about 30,868 (223)

Folic acid, either solely or combined with L‐citrulline, improves NO signaling and ameliorates chronic hypoxia‐induced pulmonary hypertension in newborn pigs

Physiological Reports, 2021
Concomitant with developing pulmonary hypertension (PH), newborn piglets exposed to chronic hypoxia develop pulmonary vascular NO signaling impairments.
Matthew Douglass, Anna Dikalova, Mark R. Kaplowitz, Yongmei Zhang, Gary Cunningham, Marshall Summar, Candice D. Fike   +6 more
doaj   +1 more source

Arginine and Citrulline for the Treatment of MELAS Syndrome

Journal of Inborn Errors of Metabolism and Screening, 2017
Mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes (MELAS) syndrome is a maternally inherited mitochondrial disease with a broad spectrum of manifestations.
Ayman W. El-Hattab MD, FACMG, Mohammed Almannai MD, Fernando Scaglia MD, FACMG   +2 more
doaj   +1 more source

L-citrulline Sebagai Inhibitor Korosi Pada Tinplate Dalam Media Nacl [PDF]

, 2016
L-citrulline sebagai inhibitor korosi pada tinplate dalam media NaCl telah diteliti menggunakan metode polarisasi potensiodinamik dan pengurangan berat. Pada penelitian ini dilakukan variasi konsentrasi L-citrulline dan media korosi NaCl.
-, H. (Harmami), Ulfin, I. -. (Ita), Zakaria, Z. A. (Zilfirdausi)   +2 more
core  

Citrulline malate supplementation does not improve German Volume Training performance or reduce muscle soreness in moderately trained males and females [PDF]

, 2018
Background Use of supplements to aid performance is common practice amongst recreationally active individuals, including those without a sufficient evidence base.
A Martinez-Sanchez, A Sureda, AF Creff, Andrew J. Chappell, Annie Anand, B Campbell, B Cunniffe, B Wax, B Wax, C Moinard, D Bendahan, D Vanuxem, DA Jones, Daniel M. Allwood, E Curis, G Wu, J Perez-Guisado, JM Glenn, Kiran Sultana, L Xie, M Ochiai, MA Janeira, PT Cutrufello, R Bescos, RA Meyer, RC Hickner, Rebecca Johns, RJ Haines, Samantha Brown, Trevor Simper   +29 more
core   +1 more source

l -Citrulline improves cerebral blood flow in migraine model rats

Journal of Functional Foods, 2017
We have previously reported that intravenous injection of l-citrulline, an α-amino acid isolated from watermelon juice, prevented the decrease in cerebral blood flow (CBF) during cortical spreading depression (CSD) in rats, a widely accepted animal model of migraine aura.
Yuki Kurauchi, Koichi Mokudai, Masahiko Morita, Ayako Kamimura, Asami Mori, Kenji Sakamoto, Tsutomu Nakahara, Kunio Ishii   +7 more
openaire   +2 more sources

Interactions of Antibody Drug Conjugate Anti‐Tubulin and Topoisomerase I Inhibitor Payloads with Radiotherapy to Potentiate Immunotherapy

Advanced Science, EarlyView.
Antibody drug conjugates deliver their cytotoxic anti‐tubulin or topoisomerase I inhibitor payloads to tumors through cancer cell receptor targeting. The released drug payloads induce cellular changes that interact with radiotherapy resulting in radiosensitization that improves cancer cell kill and stimulates anti‐tumor immune responses.
Jacqueline Lesperance, Bryan S. Yung, Michael M. Allevato, Marcus M Cheng, Maria F. Camargo, Robert Saddawi‐Konefka, Kanika Dhawan, Ashwyn K. Sharma, Mahsa Mortaja, Sophie Bice, Daniel J. Scanderbeg, Diego Alvarado, Jyoti Mayadev, Ramez N. Eskander, Stephen R. Adams, Pippa F. Cosper, J. Silvio Gutkind, Sunil J. Advani   +17 more
wiley   +1 more source

Pathogenic Role of FGFR3 Autoantibodies in Small Fiber Neuropathy

Advanced Science, EarlyView.
Autoantibodies against fibroblast growth factor receptor 3 (FGFR3) are identified as pathogenic drivers of pain in small fiber neuropathy. By binding to sensory neurons in dorsal root ganglia, FGFR3 autoantibodies activate MAPK signaling and induce hyperexcitability and mechanical hypersensitivity, establishing FGFR3 autoantibodies as a therapeutic ...
Lyuba Y. Salih, Nicolas L.A. Dumaire, Clémence Gieré, Erin Vest, Haya Alkhateeb, Christian P. Moritz, Yannick Tholance, Jean‐Philippe Camdessanché, Jean‐Christophe Antoine, Jérôme Honnorat, Jafar Kafaie, Liberty François‐Moutal, Aubin Moutal   +12 more
wiley   +1 more source

Asymmetric dimethylarginine predicts perioperative cardiovascular complications in patients undergoing medium-to-high risk non-cardiac surgery

Journal of International Medical Research, 2020
Objectives Perioperative cardiovascular events remain an important factor that affects surgery outcome. We assessed if asymmetric dimethylarginine (ADMA), an endogenous inhibitor of nitric oxide synthesis, predicts perioperative risk, and if pre ...
Daniel Appel, Rainer Böger, Julia Windolph, Gina Heinze, Alwin E. Goetz, Juliane Hannemann   +5 more
doaj   +1 more source

Activated Platelet–Released Heat Shock Protein 90α Triggers Autophagy‐Dependent Neutrophil Extracellular Trap Formation and Amplifies Sepsis

Advanced Science, EarlyView.
HSP90α is significantly upregulated in platelets from sepsis patients, with its origin from megakaryocyte‐derived trafficking. Furthermore, activated platelets secrete HSP90α into the extracellular space in both free and exosome‐associated forms. Finally, extracellular HSP90α directly engages TLR4 on neutrophils to induce autophagy, leading to NET ...
Chengbo Wang, Maodong Leng, Chenchen Sun, Jingyu Cao, Linfei Li, Yangyang Jia, Yongshuai Han, Yuchun Liu, Yaodong Zhang, Chenglong Zhang, Yingli Men, Ningyuan Liu, Yibing Cheng, Yixia Zhang, Ya Li, Zhenlong Li, Lidan Cui, Xiangzhan Zhu   +17 more
wiley   +1 more source

NEW METABOLIC PRODUCTS OF L-CITRULLINE AND L-HOMOARGININE [PDF]

Pediatric Research, 1977
Several clinical conditions associated with hyperammonemia are also characterized, in part, by elevated serum and urine levels of citrulline (C), homocitrulline (HC), and homoarginine (HA). Our previous studies on 14C-ureido-HC revealed that HC was converted by rats and mice, and, in vitro, by L-amino acid oxidase to a cyclic derivative (Fed. Proc.
Ronald W Wilson, Richard Thompson, Arthur F Kohrman   +2 more
openaire   +1 more source