Results 101 to 110 of about 13,194,872 (182)
Autoimmunity: Molecular Mechanisms, Biomarkers, and Therapeutic Opportunities
Major types of immunometabolism, epigenetics, posttranscriptional regulation, and functional reprogramming involved in autoimmune diseases. The roles of immunometabolism, epigenetics, posttranscriptional regulation, and functional reprogramming in autoimmune diseases have been a major research focus in recent years.
Jialong Kuang +10 more
wiley +1 more source
Production purification and characterization of glutaminase-free L-asparaginase from pectobacterium carotovorum MTCC 1428 [PDF]
Supervisor: V Venkata Dasu and K PakshirajanBacterial L-asparaginase has been widely used as a therapeutic agent in the treatment of certain kinds of cancer, mainly in treatment of acute lymphoblastic leukemia.
Kumar, Sanjay
core +1 more source
The halophilic bacterial isolates SS1, SS2, SS3, SS5, and SS8 were characterized for production of industrially important enzymes like amylase, protease, lipase, and glutaminase.
Sonika Gupta +3 more
doaj +1 more source
Ferroptosis: Newly Emerged Regulator for Human Disease
Ferroptosis is a key regulated cell death pathway closely involved in cancers, neurodegenerative disorders, acute organ injuries, and cardiovascular and chronic metabolic diseases, representing a promising therapeutic target for diverse human illnesses.
Dandan Xiao +4 more
wiley +1 more source
INVESTIGATION ON THE PRODUCTION OF L-GLUTAMINASE FROM PSEUDOMONAS STUTZERI STRAIN UNDER SOLID STATE FERMENTATION USING VARIOUS AGRO RESIDUES [PDF]
Solid state fermentation was carried out for the production of L-glutaminase by Pseudomonas stutzeri PIMS6 using different agro residues including green gram husk, Bengal gram husk, cattle feed, wheat bran and groundnut oil cake as solid substrates.
Athira, R N +7 more
core +1 more source
Cloning and molecular analysis of L-asparaginase II gene (ansB) [PDF]
The deamination of L-asparagine to L-aspartic acid and ammonia is catalyzed by L-asparaginases (L-asparagine amino hydrolase). The enzyme L-asparaginase is widely distributed in nature from different living organisms, starting from bacteria till mammals ...
ZEINAT K. MOHAMED +3 more
doaj
Metabolism in Tumor: Mechanisms and Therapeutic Perspectives
Tumor metabolic reprogramming converges on three hubs—the SREBP1/2–FASN–SCD1 lipogenic axis, the HIF‐1α–GLUT1–LDHA glycolytic axis, and the LDLR–SCARB1–LXR cholesterol system—which integrate transcriptional, epigenetic (histone lactylation, m6A), and microenvironmental inputs to generate metabolic plasticity, immune evasion, and therapy resistance ...
Jia‐Chen Cheng +6 more
wiley +1 more source
Fungal glutaminase is of great importance in different industries fields. Thus, searching for a significantly catalytic l-glutaminase (Glut) with appraising its biochemical properties and biotechnological applications are the main purposes of this work ...
Hamed M. El-Shora +5 more
doaj +1 more source
Amino Acid Metabolism in Health and Disease
This graphical abstract delineates the multifaceted role of amino acid metabolism in health and disease. It illustrates how amino acids sustain physiological homeostasis across the liver, kidney, brain, heart, intestine, muscle, skeleton, and immune system.
Zhiwei Su +7 more
wiley +1 more source
Background: For the past 30 years, bacterial L-asparaginases have been used as therapeutic agents in the treatment of acute childhood lymphoblastic leukemia. It is found in a variety of organisms such as microbes, plants and mammals.
Meraj Pourhossein, Hassan Korbekandi
doaj +1 more source

