Results 101 to 110 of about 13,194,872 (182)

Autoimmunity: Molecular Mechanisms, Biomarkers, and Therapeutic Opportunities

open access: yesMedComm, Volume 7, Issue 9, September 2026.
Major types of immunometabolism, epigenetics, posttranscriptional regulation, and functional reprogramming involved in autoimmune diseases. The roles of immunometabolism, epigenetics, posttranscriptional regulation, and functional reprogramming in autoimmune diseases have been a major research focus in recent years.
Jialong Kuang   +10 more
wiley   +1 more source

Production purification and characterization of glutaminase-free L-asparaginase from pectobacterium carotovorum MTCC 1428 [PDF]

open access: yes, 2010
Supervisor: V Venkata Dasu and K PakshirajanBacterial L-asparaginase has been widely used as a therapeutic agent in the treatment of certain kinds of cancer, mainly in treatment of acute lymphoblastic leukemia.
Kumar, Sanjay
core   +1 more source

Halophilic Bacteria of Lunsu Produce an Array of Industrially Important Enzymes with Salt Tolerant Activity

open access: yesBiochemistry Research International, 2016
The halophilic bacterial isolates SS1, SS2, SS3, SS5, and SS8 were characterized for production of industrially important enzymes like amylase, protease, lipase, and glutaminase.
Sonika Gupta   +3 more
doaj   +1 more source

Ferroptosis: Newly Emerged Regulator for Human Disease

open access: yesMedComm, Volume 7, Issue 9, September 2026.
Ferroptosis is a key regulated cell death pathway closely involved in cancers, neurodegenerative disorders, acute organ injuries, and cardiovascular and chronic metabolic diseases, representing a promising therapeutic target for diverse human illnesses.
Dandan Xiao   +4 more
wiley   +1 more source

INVESTIGATION ON THE PRODUCTION OF L-GLUTAMINASE FROM PSEUDOMONAS STUTZERI STRAIN UNDER SOLID STATE FERMENTATION USING VARIOUS AGRO RESIDUES [PDF]

open access: yes, 2014
Solid state fermentation was carried out for the production of L-glutaminase by Pseudomonas stutzeri PIMS6 using different agro residues including green gram husk, Bengal gram husk, cattle feed, wheat bran and groundnut oil cake as solid substrates.
Athira, R N   +7 more
core   +1 more source

Cloning and molecular analysis of L-asparaginase II gene (ansB) [PDF]

open access: yesJournal of BioScience and Biotechnology, 2015
The deamination of L-asparagine to L-aspartic acid and ammonia is catalyzed by L-asparaginases (L-asparagine amino hydrolase). The enzyme L-asparaginase is widely distributed in nature from different living organisms, starting from bacteria till mammals ...
ZEINAT K. MOHAMED   +3 more
doaj  

Metabolism in Tumor: Mechanisms and Therapeutic Perspectives

open access: yesMedComm, Volume 7, Issue 9, September 2026.
Tumor metabolic reprogramming converges on three hubs—the SREBP1/2–FASN–SCD1 lipogenic axis, the HIF‐1α–GLUT1–LDHA glycolytic axis, and the LDLR–SCARB1–LXR cholesterol system—which integrate transcriptional, epigenetic (histone lactylation, m6A), and microenvironmental inputs to generate metabolic plasticity, immune evasion, and therapy resistance ...
Jia‐Chen Cheng   +6 more
wiley   +1 more source

Purification and biochemical characterization of l-glutaminase from Aspergillus oryzae with potential biotechnological applications in synthesis of l-theanine and as antitumor agent

open access: yesScientific Reports
Fungal glutaminase is of great importance in different industries fields. Thus, searching for a significantly catalytic l-glutaminase (Glut) with appraising its biochemical properties and biotechnological applications are the main purposes of this work ...
Hamed M. El-Shora   +5 more
doaj   +1 more source

Amino Acid Metabolism in Health and Disease

open access: yesMedComm, Volume 7, Issue 9, September 2026.
This graphical abstract delineates the multifaceted role of amino acid metabolism in health and disease. It illustrates how amino acids sustain physiological homeostasis across the liver, kidney, brain, heart, intestine, muscle, skeleton, and immune system.
Zhiwei Su   +7 more
wiley   +1 more source

Cloning, expression, purification and characterisation of Erwinia carotovora L-asparaginase in Escherichia coli

open access: yesAdvanced Biomedical Research, 2014
Background: For the past 30 years, bacterial L-asparaginases have been used as therapeutic agents in the treatment of acute childhood lymphoblastic leukemia. It is found in a variety of organisms such as microbes, plants and mammals.
Meraj Pourhossein, Hassan Korbekandi
doaj   +1 more source

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