Results 81 to 90 of about 12,654 (140)

Enzymatic properties of a L-asparaginase without secondary glutaminase activity from Streptomyces scabrisporus.

PLoS ONE
Acute lymphocytic leukemia (ALL) is characterized by the uncontrolled proliferation of lymphocyte precursor cells within the bone marrow, blood and extramedullary sites. L-asparaginase has become a standard treatment in childhood cases of ALL by reducing
Ricardo Rodríguez-Vargas, Francisca Villanueva-Flores, María Fernanda Gutiérrez-Chávez, Carlos Medrano-Villagómez, Andrés Zárate-Romero, Alejandro Huerta-Saquero   +5 more
doaj   +1 more source

Marine Bacteria Producing L-Asparaginase with Low Glutaminase and Urease Co-Activity from Pangandaran East Coast Indonesia

Squalen
acterial L-asparaginase is a therapeutic enzyme widely used in the treatment of Acute Lymphoblastic Leukemia (ALL). Although L-asparaginase is prominent in treating ALL, its use is limited due to its side effects caused by its dual substrate specificity ...
Wulan Pertiwi, Azmy Jasmine Namira, Maelita Ramdani Moeis, Luthfia Hastiani Muharram, Nelis Hernahadini   +4 more
doaj   +1 more source

Design-build-test of recombinant Bacillus subtilis chassis cell by lifespan engineering for robust bioprocesses

Synthetic and Systems Biotechnology
Microbial cell factories utilize renewable raw materials for industrial chemical production, providing a promising path for sustainable development. Bacillus subtilis is widely used in industry for its food safety properties, but challenges remain in the
Kexin Ren, Qiang Wang, Jianghua Chen, Hengwei Zhang, Zhoule Guo, Meijuan Xu, Zhiming Rao, Xian Zhang   +7 more
doaj   +1 more source

Novel halo- and thermo-tolerant Cohnella sp. A01 L-glutaminase: heterologous expression and biochemical characterization. [PDF]

Sci Rep, 2019
Mosallatpour S, Aminzadeh S, Shamsara M, Hajihosseini R.   +3 more
europepmc   +1 more source

Design and Characterization of Erwinia Chrysanthemi l-Asparaginase Variants with Diminished l-Glutaminase Activity. [PDF]

J Biol Chem, 2016
Nguyen HA, Su Y, Lavie A.
europepmc   +1 more source

Enhancement of the production of L-glutaminase, an anticancer enzyme, from Aeromonas veronii by adaptive and induced mutation techniques. [PDF]

PLoS One, 2017
Jesuraj SAV, Sarker MMR, Ming LC, Praya SMJ, Ravikumar M, Wui WT.   +5 more
europepmc   +1 more source

Revolutionizing cancer treatment with Halomonas Aquamarina L-Glutaminase: insights from in vitro and computational studies. [PDF]

Sci Rep
Abdelsayed S, Elmetwalli A, Hassan J, Monem MOA, El-Far AH, Ameen F, Hassan MG.   +6 more
europepmc   +1 more source

Recombinant l-glutaminase obtained from Geobacillus thermodenitrificans DSM-465: characterization and in silico elucidation of conserved structural domains. [PDF]

RSC Adv, 2019
Shah L, Nadeem MS, Khan JA, Zeyadi MA, Zamzami MA, Mohammed K.   +5 more
europepmc   +1 more source

Kinetic properties of Streptomyces canarius L- Glutaminase and its anticancer efficiency. [PDF]

Braz J Microbiol, 2015
Reda FM.
europepmc   +1 more source