Results 11 to 20 of about 13,194,872 (182)

Studies on Characteristic of Extracellular L–Glutaminase and Identification of L-Glutaminase Producing Bacterial Strain from Cattle Feeding Farm of Chhatrapati Sambhajinagar, Maharashtra State, India [PDF]

Journal of Advanced Zoology, 2023
L-glutaminase is gaining marked importance due to its potential clinical applications. A variety of microorganisms, including bacteria, yeast, and lamentous fungi, from soil habitat have been reported to produce L-glutaminase. The present investigation was carried out to isolate and screening of L-glutamiase producing bacteria from soil samples of ...
null Bhalchandra B. Waykar, Trupti Namekar, null Rajendra A. Satpute, null Dinesh S. Kharate   +3 more
openaire   +2 more sources

New application of microbial l-glutaminase as a flavor enhancing agent in beef burgers [PDF]

Теория и практика переработки мяса, 2022
L‑glutaminase (L‑glutamine amidohydrolase EC3.5.1.2) is the key enzyme in enhancing the taste and aroma of oriental fermented foods by increasing their glutamic acid content and as a result imparting a palatable taste.
R. M. Mohamed, W. A. Bazaraa, A. M. Alian, N. M. EL-Shimi   +3 more
doaj   +2 more sources

Metabolic Heterogeneity, Plasticity, and Adaptation to “Glutamine Addiction” in Cancer Cells: The Role of Glutaminase and the GTωA [Glutamine Transaminase—ω-Amidase (Glutaminase II)] Pathway

Biology, 2023
Many cancers utilize l-glutamine as a major energy source. Often cited in the literature as “l-glutamine addiction”, this well-characterized pathway involves hydrolysis of l-glutamine by a glutaminase to l-glutamate, followed by oxidative deamination, or
Arthur J. L. Cooper, Thambi Dorai, John T. Pinto, Travis T. Denton   +3 more
doaj   +2 more sources

Evaluating Therapeutic Characteristics of Anticancer L -Glutaminase Enzyme on Ethylenimine Induced Mutagens in Rats. [PDF]

Kirkuk Journal of Science, 2018
This study include, the partial purification of L-glutaminase enzyme from E.coli by ammonium sulphate precipitation (40%-80%) fractions, and the enzyme activity elevated to 75 IU/ml following dialysis.
Gulbahar Karim, Karkaz Thalij
doaj   +3 more sources

Molecular Evaluating the Therapeutic Application of Anticancer L-glutaminase Enzyme on Genetic Mutation Induced Rats

Tikrit Journal for Agricultural Sciences, 2021
The Genomic DNA had been extracted from the liver tissue of the experimental rat groups following 15 weeks of treatment with partial purified L-glutaminase enzyme from E.coli in relation with ethylamine.
Abdalkaleq K. Suleman, Gulbahar F. Karim, Saad Dhamin Oleiwi, Karkaz M. Thalij   +3 more
doaj   +2 more sources

Evidence of Antioxidant Activity of Novel L-Glutaminase Purified from L. Gasseri BRLHM [PDF]

Journal of Applied Sciences and Nanotechnology, 2021
Probiotic strains have the potential to be used as bio-preservatives and functional radical scavenging treatments in the future.  Antioxidant tests, including DPPH radical scavenging, were used to evaluate the antioxidant effects of extracellular L ...
Butheina Hasson, Likaa Mahdi, Rajwa Essa
doaj   +1 more source

Immunogenicity assessment of antileukemic agent glutaminase from Escherichia coli, Pseudomonas sp., and Bacillus sp.

Biomedical and Biotechnology Research Journal, 2022
Background: L-glutaminase (L-glutaminase or glutamine amidohydrolase: EC 3.5.1.2) is an antileukemic agent which catalyzes the deamidation of glutamine to glutamic acid and ammonia.
Jyotsna Parmar, Shikha Tripathi, Awanish Kumar   +2 more
doaj   +1 more source

Optimizing the Production of Glutaminase-Free L-Asparaginase by Halotolerant Penicillium sp. Isolated from Halophyte Cogongrass Rhizosphere [PDF]

Delta Journal of Science, 2023
L-asparaginase is an enzyme included in the treatment of acute lymphoblastic leukemia (ALL). Its thrabiutic mechanism is the hydrolyzes of l-asparagine, which is essential amino acid for neoplastic cells while not essential and can be synthesized by ...
Abd El-Raheem El-Shanshoury, Hadeer Abosamra, Tamer ElSakhawy   +2 more
doaj   +1 more source

In vitro Cytocidal Effect of L-Glutaminase on Leukaemic Lymphocytes [PDF]

Nature, 1971
MOUSE lymphomas, such as 6C3HED, undergo complete regression after one or more injections of L-asparaginase1, and remissions have been reported in some patients with acute leukaemia after treatment with L-asparaginase2–4. Roberts et al.5 found that purified bacterial L-glutaminase inhibited the growth of Ehrlich mouse carcinoma. Before considering this
R, Schrek, J S, Holcenberg, J, Roberts, W C, Dolowy   +3 more
openaire   +2 more sources

L-Glutaminase Synthesis by Marine Halomonas meridiana Isolated from the Red Sea and Its Efficiency against Colorectal Cancer Cell Lines

Molecules, 2021
L-glutaminase is an important anticancer agent that is used extensively worldwide by depriving cancer cells of L-glutamine. The marine bacterium, Halomonas meridian was isolated from the Red Sea and selected as the more active L-glutaminase-producing ...
Yasser S. Mostafa, Saad A. Alamri, Mohammad Y. Alfaifi, Sulaiman A. Alrumman, Serag Eldin I. Elbehairi, Tarek H. Taha, Mohamed Hashem   +6 more
doaj   +1 more source