Results 31 to 40 of about 11,907 (183)
New application of microbial l-glutaminase as a flavor enhancing agent in beef burgers
Теория и практика переработки мяса, 2022 L‑glutaminase (L‑glutamine amidohydrolase EC3.5.1.2) is the key enzyme in enhancing the taste and aroma of oriental fermented foods by increasing their glutamic acid content and as a result imparting a palatable taste.
R. M. Mohamed +3 more
doaj +1 more source
Purification and properties of L-glutaminase-L-asparaginase from Pseudomonas acidovorans [PDF]
Journal of Bacteriology, 1977 An enzyme that catalyzes the hydrolysis of both glutamine and asparagine has been purified to homogeneity from extracts of Pseudomonas acidovorans. The enzyme having a ratio of glutaminase to asparaginase of 1.45:1.0 can be purified by a relatively simple procedure and is stable upon storage.
L, Davidson +4 more
openaire +2 more sources
Engineering of Helicobacter pylori L-asparaginase: characterization of two functionally distinct groups of mutants. [PDF]
PLoS ONE, 2015 Bacterial L-asparaginases have been used as anti-cancer drugs for over 4 decades though presenting, along with their therapeutic efficacy, several side effects due to their bacterial origin and, seemingly, to their secondary glutaminase activity ...
Maristella Maggi +3 more
doaj +1 more source
TNF-α promotes extracellular vesicle release in mouse astrocytes through glutaminase
Journal of Neuroinflammation, 2017 Background Extracellular vesicles (EVs) are membrane-contained vesicles shed from cells. EVs contain proteins, lipids, and nucleotides, all of which play important roles in intercellular communication.
Kaizhe Wang +6 more
doaj +1 more source
PLoS ONE, 2023 L-asparaginase (L-ASNase) is a versatile anticancer and acrylamide reduction enzyme predominantly used in medical and food industries. However, the high specificity of L-asparaginase formulations for glutamine, low thermostability, and blood clearance ...
Ifrah Shafqat +7 more
doaj +1 more source
Pharmaceutics, 2021 l-asparaginase is an enzyme used as treatment for acute lymphoblastic leukemia (ALL) due to its ability to hydrolyze l-asparagine, an essential amino acid synthesized by normal cells unlike neoplastic cells.
Marcela Freitas +9 more
doaj +1 more source
Journal of Advanced Zoology, 2023 L-glutaminase is gaining marked importance due to its potential clinical applications. A variety of microorganisms, including bacteria, yeast, and lamentous fungi, from soil habitat have been reported to produce L-glutaminase. The present investigation was carried out to isolate and screening of L-glutamiase producing bacteria from soil samples of ...
null Bhalchandra B. Waykar +3 more
openaire +1 more source
DL-3-n-butylphthalide enhances synaptic plasticity in mouse model of brain impairments
STEMedicine, 2022 Synaptic impairment results in cognitive dysfunction of Alzheimer’s disease (AD). As a plant extract, it is found that DL-3-n-butylphthalide (L-NBP) rescues abnormal cognitive behaviors in AD animals.
Qian Ding +5 more
doaj +1 more source
Journal of Taibah University for Science, 2021 Several bacterial strains were isolated from soil and water in the current work and screened for glutaminase-free L-asparaginase activity. The selected strain was subjected to the production of glutaminase-free L-asparaginase and thereby purification ...
Pragya Prakash +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source