Results 21 to 30 of about 12,654 (140)
Squalen, 2013 L-glutaminase (L-glutamine amidohydrolase, EC 3.5.1.2) is a very important enzyme due to its role as flavor enhancer and antileukemic agent. Salt-tolerant L-glutaminase produced by marine bacteria is favorable in food industries. This study describes the
Ekowati Chasanah +2 more
doaj +1 more source
Optimization Of Culture Conditions For Maximizing L-glutaminase Production From The Marine Fungus Aspergillus flavus [PDF]
Delta Journal of ScienceMarine fungi have the capacity to extreme environments and live in a highly competitive ecological position make them suppliers of novel metabolites as L-glutaminase which is medically useful in the pharmaceutical industry, as an antioxidant and ...
Omyma Awadalla +3 more
doaj +1 more source
L-Asparaginase from Penicillium sizovae Produced by a Recombinant Komagataella phaffii Strain
Pharmaceuticals, 2022 L-asparaginase is an important enzyme in the pharmaceutical field used as treatment for acute lymphoblastic leukemia due to its ability to hydrolyze L-asparagine, an essential amino acid synthesized by normal cells, but not by neoplastic cells.
Marcela Freitas +10 more
doaj +1 more source
F1000Research, 2020 Background: The mangrove, Rhizophora mucronata, an essential source of endophytic bacteria, was investigated for its ability to produce glutaminase-free L-asparaginase.
Asep Awaludin Prihanto +3 more
doaj +1 more source
New application of microbial l-glutaminase as a flavor enhancing agent in beef burgers
Теория и практика переработки мяса, 2022 L‑glutaminase (L‑glutamine amidohydrolase EC3.5.1.2) is the key enzyme in enhancing the taste and aroma of oriental fermented foods by increasing their glutamic acid content and as a result imparting a palatable taste.
R. M. Mohamed +3 more
doaj +1 more source
A Novel L-Asparaginase from Enterobacter sp. Strain M55 from Maras Salterns in Peru [PDF]
Chemical and Biochemical Engineering Quarterly, 2022 L-Asparaginase (ASNase) is used in medicine for neoplasms treatment and in food industry for mitigation of acrylamide in high-temperature processed food.
A. Hurtado +8 more
doaj +1 more source
Engineering of Helicobacter pylori L-asparaginase: characterization of two functionally distinct groups of mutants. [PDF]
PLoS ONE, 2015 Bacterial L-asparaginases have been used as anti-cancer drugs for over 4 decades though presenting, along with their therapeutic efficacy, several side effects due to their bacterial origin and, seemingly, to their secondary glutaminase activity ...
Maristella Maggi +3 more
doaj +1 more source
Dendritic Cell α-Ketoglutarate Regulates Tfh Polarization in Allergy. [PDF]
AllergyAllergen induces a dendritic cell metabolism shift toward glutaminolysis with α‐ketoglutarate as a regulator of Tfh subset polarization. Glutaminolysis is required for DC allergen uptake, co‐stimulatory molecule expression, and CLR expression. Modulation of glutaminolysis, JmjD3 histone demethylation, or HIF‐1α degradation alters Tfh polarization and ...
Tharakan A +16 more
europepmc +2 more sources
TNF-α promotes extracellular vesicle release in mouse astrocytes through glutaminase
Journal of Neuroinflammation, 2017 Background Extracellular vesicles (EVs) are membrane-contained vesicles shed from cells. EVs contain proteins, lipids, and nucleotides, all of which play important roles in intercellular communication.
Kaizhe Wang +6 more
doaj +1 more source
PLoS ONE, 2023 L-asparaginase (L-ASNase) is a versatile anticancer and acrylamide reduction enzyme predominantly used in medical and food industries. However, the high specificity of L-asparaginase formulations for glutamine, low thermostability, and blood clearance ...
Ifrah Shafqat +7 more
doaj +1 more source