Results 21 to 30 of about 13,194,872 (182)
Scientific Reports, 2021 l-Asparaginase is a therapeutically and industrially-competent enzyme, acting predominantly as an anti-neoplastic and anti-cancerous agent. The existing formulations of prokaryotic l-asparaginase are often toxic and contain l-glutaminase and urease ...
Meghna Chakraborty, Srividya Shivakumar
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Haematologica, 2022 Asparagine is a non-essential amino acid since it can either be taken up via the diet or synthesized by asparagine synthetase. Acute lymphoblastic leukemia (ALL) cells do not express asparagine synthetase or express it only minimally, which makes them ...
Maaike Van Trimpont +16 more
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Isolation and Characterization of L-Glutaminase producing Bacteria [PDF]
, 2020 Abstract Being a significant protein L-glutaminases discovers potential applications in various divisions running from nourishment industry to restorative and cure. It is generally disseminated in microbes, actinomycetes, yeast and organisms. Glutaminase is the principal enzyme that changes glutamine to glutamate. The
Rabia Saleem, Safia Ahmed
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Journal of Pure and Applied Microbiology, 2023 Marine fungi are important sources of new metabolites including certain enzymes of medical interest due to their enormous capacity to adapt themselves to extreme environments.
Sumangala Rao +3 more
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Production, optimization and characterization of L-glutaminase from marine bacteria [PDF]
, 2019 L-glutaminase present in living organisms. L-glutaminase has been identified having potential applications for several industries including pharmaceutical, food, and health care.
Nur Dini, Johari
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PURIFICATION, CHARACTERIZATION STUDIES OF L-GLUTAMINASE FROM ASPERGILLUS FLAVUS STRAIN S4 [PDF]
, 2023 L-glutaminase [EC.3.5.1.2] is an amidohydrolase that catalyzes the hydrolytic deamination of L-glutamine, resulting in the production of L-glutamic acid and ammonia.
Hemalatha Vinjarapu, Anil Saragonda, Sowjanya muthyam, Kalyani Pullapukuri
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Genomic organization and transcriptional analysis of the human l-glutaminase gene [PDF]
Biochemical Journal, 2003 In mammals, glutaminase (GA) is expressed in most tissues, but the regulation of organ-specific expression is largely unknown. Therefore, as an essential step towards studying the regulation of GA expression, the human liver-type GA (hLGA) gene has been characterized. LGA genomic sequences were isolated using the genome walking technique.
Cristina, Pérez-Gómez +5 more
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Optimization Of Culture Conditions For Maximizing L-glutaminase Production From The Marine Fungus Aspergillus flavus [PDF]
Delta Journal of ScienceMarine fungi have the capacity to extreme environments and live in a highly competitive ecological position make them suppliers of novel metabolites as L-glutaminase which is medically useful in the pharmaceutical industry, as an antioxidant and ...
Omyma Awadalla +3 more
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, 2020 L-asparaginase (ASNase) is an essential drug in the treatment of acute lymphoblastic leukemia (ALL). Commercial bacterial ASNases increase patient survival, but the consequent immunological reactions remain a challenge.
Rafael Bertelli Ferraro (9370271) +8 more
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, 2021 A comprehensive research has been carried out on L-glutaminase producers from marine bacteria. Among the evaluated isolates, Kosakonia radicincitans was found to be a L-glutaminase producer from a marine environment, having the highest enzymatic ...
Aizi Nor Mazila, Ramli +4 more
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