Results 181 to 190 of about 714,437 (290)

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Retraction: Neuroprotective Role of L-NG-Nitroarginine Methyl Ester (L-NAME) against Chronic Hypobaric Hypoxia with Crowding Stress (CHC) Induced Depression-Like Behaviour. [PDF]

PLoS One
PLOS One Editors.
europepmc   +1 more source

Effects of Mineralocorticoid Receptor Blockade and Statins on Kidney Injury Marker 1 (KIM-1) in Female Rats Receiving L-NAME and Angiotensin II. [PDF]

Int J Mol Sci, 2023
Huang J, Caliskan Guzelce E, Gholami SK, Gawelek KL, Mitchell RN, Pojoga LH, Romero JR, Williams GH, Adler GK.   +8 more
europepmc   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

TRPC6 Deficiency Attenuates Mitochondrial and Cardiac Dysfunction in Heart Failure with Preserved Ejection Fraction Induced by High-Fat Diet Plus L-NAME. [PDF]

Int J Mol Sci
Li X, Fu Y, Dai X, do Carmo JM, da Silva AA, Mouton AJ, Omoto ACM, Spitz RW, Wang L, Hall JE, Wang Z.   +10 more
europepmc   +1 more source

Antihypertensive Activity of Milk Fermented by Lactiplantibacillus plantarum SR37-3 and SR61-2 in L-NAME-Induced Hypertensive Rats [PDF]

Foods, 2022
Yuan L, Li Y, Chen M, Xue L, Wang J, Ding Y, Zhang J, Wu S, Ye Q, Zhang S, Yang R, Zhao H, Wu L, Liang T, Xie X, Wu Q.   +15 more
europepmc   +1 more source

L-NAME ile hipertansiyon oluşturulmuş sıçanlarda gallik asit enjeksiyonunun etkisi

, 2011
The present study aims to investigate that effects of gallic acid on experimental inducedhypertension induced with L-NAME in rats.60 ten-week old female Spraque Dawley rats were used in this study, which werecategorized into 6 different groups of equal numbers.
openaire   +2 more sources

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Decreased blood pressure with acute administration of quercetin in L-NAME-induced hypertensive rats. [PDF]

Basic Clin Pharmacol Toxicol
Mkhize SA, Nthlane RA, Xhakaza SP, Verhaert PD, Baijnath S, Millen AME, Michel FS.   +6 more
europepmc   +1 more source

Phytochemical characterization, antioxidant activity and antihypertensive evaluation of <i>Ocimum basilicum</i> L. in l-NAME induced hypertensive rats and its correlation analysis. [PDF]

Heliyon, 2023
Qamar F, Sana A, Naveed S, Faizi S.
europepmc   +1 more source