Results 41 to 50 of about 13,368,448 (174)
P-selectin expression tracks cerebral atrophy in Mexican-Americans
Frontiers in Genetics, 2012 Background and Purpose. We hypothesized that the P-selectin (SELP) gene, localized to a region on chromosome 1q24, pleiotropically contributes to increased blood pressure (BP) and cerebral atrophy.
Peter eKochunov +18 more
doaj +1 more source
Czech Journal of Animal Science, 2007 Localization of the L-selectin (CD62L) and β2-integrin (CD18) bearing cells in different tissues of the bovine mammary gland was examined. Five dairy cows of Holstein-Friesian breed in the middle of their second and third lactation cycle were used in the
M. Simon +4 more
doaj +1 more source
L-Selectin−Carbohydrate Interactions: Relevant Modifications of the Lewis x Trisaccharide†
, 2016 Protein−carbohydrate interactions are known to mediate cell−cell recognition and adhesion events. Specifically, three carbohydrate binding proteins termed selectins (E-, P-, and L-selectin) have been shown to be essential for leukocyte rolling along the ...
Tamiko R. Katsumoto (2948751) +4 more
core +1 more source
Synthesis of a Potent Antagonist of E-Selectin
, 2016 A synthesis of an antagonist of E-selectin previously reported by a group at Novartis Pharma in Basel is described. An important feature involves the formation of an ether linkage based on a RhII-catalyzed reaction.
Vincent Mascitti (1393702) +2 more
core +2 more sources
L-selectin ligands involved in the extravasation on tumor cells [PDF]
, 2011 Metastasis is the major problem of cancer, since this process constitutes the systemic spread of a formerly located pathological situation. Malignant tumor cells detach from the primary tumor site and migrate through the extracellular matrix (ECM). Tumor
Seelandt, Christian Lothar
core +2 more sources
Lung-Derived Selectins Enhance Metastatic Behavior of Triple Negative Breast Cancer Cells
Biomedicines, 2021 The lung is one of the deadliest sites of breast cancer metastasis, particularly for triple negative breast cancer (TNBC). We have previously shown that the lung produces several soluble factors that may enhance the metastatic behavior of TNBC, including
Sami U. Khan +4 more
doaj +1 more source
CLINICAL AND IMMUNOLOGICAL CHANGES IN TREATMENT OF ADENOMYOSIS IN PATIENTS WITH INFERTILITY
Кубанский научный медицинский вестник, 2017 Aim. The aim of this study was to asses changes of adhesion molecules (L-selectin, neopterin and interleukin-6) in patients with adenomyosis-related infertility during the therapy.Materials and methods.
L. Yu. KARAKHALIS +3 more
doaj +1 more source
TWO PATHWAYS OF SHEDDING OF L-SELECTIN AND CD23 FROM HUMAN B-LYMPHOCYTES [PDF]
, 2000 Lymphocytes from patients with B-chronic lymphocytic leukemia (B-CLL) express large numbers of P2X7 receptors for extracellular adenosine triphosphate (ATP).
Gu, Baijun
core
ADAM-17-independent shedding of L-selectin [PDF]
Journal of Leukocyte Biology, 2003 Abstract L-selectin is expressed by leukocytes and facilitates their adhesion under flow along the walls of blood vessels. As do a variety of membrane proteins, L-selectin undergoes ectodomain shedding. Using approaches that monitor full-length L-selectin in short-term assays, it has been determined that L-selectin shedding is defective ...
Bruce, Walcheck +3 more
openaire +2 more sources
Vascular and Non-Vascular Ligands for L-selectin [PDF]
Cell Adhesion and Communication, 1998 Ligands for L-selectin are expressed not only on vascular endothelial cells but also in the extravascular tissues. In this article, we summarize the current understanding of the "vascular" ligands for L-selectin. We also describe identification of "non-vascular" ligands for L-selectin and discuss their possible biological significance.
H, Kawashima +5 more
openaire +2 more sources