Results 41 to 50 of about 56,730 (260)

In vitro and in vivo effects of salbutamol on neutrophil function in acute lung injury [PDF]

open access: yes, 2006
Background: Intravenous salbutamol (albuterol) reduces lung water in patients with the acute respiratory distress syndrome (ARDS). Experimental data show that it also reduces pulmonary neutrophil accumulation or activation and inflammation in ARDS ...
McAuley, Daniel F.   +4 more
core   +1 more source

Chemoattractant Receptor-induced Phosphorylation of L-selectin [PDF]

open access: yesJournal of Biological Chemistry, 1997
The selectin adhesion molecules and chemoattractant receptors synergistically regulate leukocyte migration into lymphoid tissues and sites of inflammation, but little is known about how these families of receptors modulate each other's function. In this study, L-selectin was found to be phosphorylated in lymphoblastoid cell lines, and phosphorylation ...
Haribabu, Bodduluri   +5 more
openaire   +3 more sources

Ccl2 and Ccl3 Mediate Neutrophil Recruitment via Induction of Protein Synthesis and Generation of Lipid Mediators [PDF]

open access: yes, 2009
Objective: Although the chemokines monocyte chemoattractant protein-1 (Ccl2/JE/MCP-1) and macrophage inflammatory protein-1α (Ccl3/MIP-1α) have recently been implicated in neutrophil migration, the underlying mechanisms remain largely unclear.
Berberich, Nina   +7 more
core   +1 more source

Stem Cell Enrichment with Selectin Receptors: Mimicking the pH Environment of Trauma

open access: yesSensors, 2013
The isolation of hematopoietic stem and progenitor cells (HSPCs) is critical for transplantation therapy and HSPC research, however current isolation techniques can be prohibitively expensive, time-consuming, and produce variable results. Selectin-coated
Michael R. King   +3 more
doaj   +1 more source

Systematic Chemoenzymatic Synthesis of O-Sulfated Sialyl Lewis x Antigens. [PDF]

open access: yes, 2015
O-Sulfated sialyl Lewis x antigens play important roles in nature. However, due to their structural complexity, they are not readily accessible by either chemical or enzymatic synthetic processes.
Chen, Xi   +8 more
core   +1 more source

Toll-Like Receptor induced CD11b and L-selectin response in patients with coronary artery disease. [PDF]

open access: yesPLoS ONE, 2013
Toll-Like Receptor (TLR) -2 and -4 expression and TLR-induced cytokine response of inflammatory cells are related to atherogenesis and atherosclerotic plaque progression.
Ellen H A M Elsenberg   +10 more
doaj   +1 more source

The marginated pool [PDF]

open access: yes, 2002
The pulmonary circulation harbors a large intravascular reservoir of leukocytes refered to as the Marginated Pool. This marginated pool is balanced by propeling and retaining forces acting on leukocytes during their passage through the pulmonary ...
Goetz, Alwin Eduard   +1 more
core   +1 more source

ADAM-17-independent shedding of L-selectin [PDF]

open access: yesJournal of Leukocyte Biology, 2003
Abstract L-selectin is expressed by leukocytes and facilitates their adhesion under flow along the walls of blood vessels. As do a variety of membrane proteins, L-selectin undergoes ectodomain shedding. Using approaches that monitor full-length L-selectin in short-term assays, it has been determined that L-selectin shedding is defective ...
Bruce, Walcheck   +3 more
openaire   +2 more sources

P-selectin expression tracks cerebral atrophy in Mexican-Americans

open access: yesFrontiers in Genetics, 2012
Background and Purpose. We hypothesized that the P-selectin (SELP) gene, localized to a region on chromosome 1q24, pleiotropically contributes to increased blood pressure (BP) and cerebral atrophy.
Peter eKochunov   +18 more
doaj   +1 more source

The proinflammatory activity of recombinant serum amyloid A is not shared by the endogenous protein in the circulation.

open access: yes, 2010
OBJECTIVE: Elevated serum levels of the acute-phase protein serum amyloid A (SAA) are a marker for active rheumatoid arthritis (RA), and SAA can also be found in the tissues of patients with active RA.
Björkman, Lena   +5 more
core   +1 more source

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