Results 51 to 60 of about 56,730 (260)

Sulfhydryl Regulation of L-Selectin Shedding: Phenylarsine Oxide Promotes Activation-Independent L-Selectin Shedding from Leukocytes [PDF]

The Journal of Immunology, 2000
AbstractThe L-selectin adhesion molecule mediates leukocyte recruitment to inflammatory sites and lymphocyte trafficking through the peripheral lymph nodes. In response to leukocyte activation, L-selectin is proteolytically released from the cell surface, disabling leukocytes from the subsequent L-selectin-dependent interactions.
T A, Bennett, B S, Edwards, L A, Sklar, S, Rogelj   +3 more
openaire   +2 more sources

Immunohistochemical localization of adhesion molecules (CD62 and CD18) in the mammary gland of dairy cows

Czech Journal of Animal Science, 2007
Localization of the L-selectin (CD62L) and β2-integrin (CD18) bearing cells in different tissues of the bovine mammary gland was examined. Five dairy cows of Holstein-Friesian breed in the middle of their second and third lactation cycle were used in the
M. Simon, S. Hluchý, Ľ. Horovská, J. Antalíková, J. Čuboň   +4 more
doaj   +1 more source

Combining Genome Wide Association Studies and Differential Gene Expression Data Analyses Identifies Candidate Genes Affecting Mastitis Caused by Two Different Pathogens in the Dairy Cow [PDF]

, 2015
Mastitis is a costly disease which hampers the dairy industry. Inflammation of the mammary gland is commonly caused by bacterial infection, mainly Escherichia coli, Streptococcus uberis and Staphylococcus aureus.
Chen, X, Cheng, Z R, Wathes, D C, Werling, D, Zhang, S   +4 more
core   +3 more sources

The transcriptional activator Gli2 modulates T-cell receptor signalling through attenuation of AP-1 and NFκB activity [PDF]

, 2015
Different tissues contain diverse and dynamic cellular niches, providing distinct signals to tissue-resident or migratory infiltrating immune cells.
Agathocleous, Alcedo, Aza-Blanc, Bai, Bellavia, Boyman, Brennan, Buckland, Chan, Cheng, Crompton, D'Acquisto, de la Roche, Decker, Dennler, Drakopoulou, El Andaloussi, Feske, Finetti, Furler, Furmanski, Furmanski, Gilmour, Hafezi-Moghadam, Hager-Theodorides, Hager-Theodorides, Hatayama, Huang, Hui, Huse, Ingham, Jiang, Kahn, Kasper, Kim, Kumabe, Lau, Le, Lee, Li, Lowrey, Marigo, Matise, Medyouf, Michel, Mo, Neumann, Nielsen, Outram, Park, Perry, Pola, Priatel, Priatel, Reynolds, Riobó, Rohatgi, Rowbotham, Rowbotham, Rowbotham, Sacedón, Sacedón, Sato, Seo, Shah, Shimizu, Smith, Smith-Garvin, Stewart, Thompson, Varjosalo, Wakelin, Yamane   +72 more
core   +10 more sources

Lung-Derived Selectins Enhance Metastatic Behavior of Triple Negative Breast Cancer Cells

Biomedicines, 2021
The lung is one of the deadliest sites of breast cancer metastasis, particularly for triple negative breast cancer (TNBC). We have previously shown that the lung produces several soluble factors that may enhance the metastatic behavior of TNBC, including
Sami U. Khan, Ying Xia, David Goodale, Gabriella Schoettle, Alison L. Allan   +4 more
doaj   +1 more source

Perivascular mast cells regulate vein graft neointimal formation and remodeling [PDF]

, 2015
Objective. Emerging evidence suggests an important role for mast cells in vein graft failure. This study addressed the hypothesis that perivascular mast cells regulate in situ vascular inflammatory and proliferative responses and subsequent vein graft ...
Cambrook, Helen, Carberry, Jaclyn, Grassia, Gianluca, Ialenti, Armando, Kennedy, Simon, Lawrence, Catherine, MacRitchie, Neil, Maffia, Pasquale, Wadsworth, Roger M., Wu, Junxi   +9 more
core   +3 more sources

Differential L-Selectin Binding Activities of Human Hematopoietic Cell L-Selectin Ligands, HCELL and PSGL-1 [PDF]

Journal of Biological Chemistry, 2001
Expression of L-selectin on human hematopoietic cells (HC) is associated with a higher proliferative activity and a more rapid engraftment after hematopoietic stem cell transplantation. Two L-selectin ligands are expressed on human HCs, P-selectin glycoprotein ligand-1 (PSGL-1) and a specialized glycoform of CD44 (hematopoietic cell E- and L-selectin ...
C J, Dimitroff, J Y, Lee, K S, Schor, B M, Sandmaier, R, Sackstein   +4 more
openaire   +2 more sources

Simvastatin Restores Uteroplacental Hemodynamics and Trophoblast Function in Obstetric Antiphospholipid Syndrome in a Placenta‐on‐a‐Chip Model

Advanced Healthcare Materials, EarlyView.
Simvastatin mitigates placental hypoperfusion in OAPS by ameliorating abnormal uteromaternal hemodynamics and enhancing trophoblast invasion via optimized endothelial cell interactions under pathological shear stress, as evidenced by results from a placenta‐on‐a‐chip platform.
Hongli Liu, Yuan Wang, Yanjun Cai, Ruixin Guo, Shunhua Liu, Tingting Chen, Tingting Sun, Ruiheng Huo, Tengwei Liu, Qingfeng Lv, Xietong Wang   +10 more
wiley   +1 more source

CLINICAL AND IMMUNOLOGICAL CHANGES IN TREATMENT OF ADENOMYOSIS IN PATIENTS WITH INFERTILITY

Кубанский научный медицинский вестник, 2017
Aim. The aim of this study was to asses changes of adhesion molecules (L-selectin, neopterin and interleukin-6) in patients with adenomyosis-related infertility during the therapy.Materials and methods.
L. Yu. KARAKHALIS, A. R. JHIGALENKO, G. A. PENJHOYAN, N. V. KOLESNIKOVA   +3 more
doaj   +1 more source

Differences in leukocyte profile, gene expression, and metabolite status of dairy cows with or without sole ulcers [PDF]

, 2014
peer-reviewedSole ulcers are one of the most severe pathologies causing lameness in dairy cows and are associated with abnormal behavior and impaired production performance.
Aggarwal, Almeida, Almeida, Alsemgeest, Apple, Arya, Bernadette Earley, Bicalho, Bicalho, Buckham Sporer, Buckham-Sporer, Burton, Chao, Chen, Cooray, Davis, Derveaux, Fell, Fujishima, Galyean, Godson, Hart, Hellemans, Janeway, Jawor, Kansas, Keelin O’Driscoll, Knott, Kossaibati, Kulberg, Leeman, Lischer, Lischer, Matthew McCabe, McDowell, Moore, Murray, Nagata, Nocek, Opal, O’Driscoll, O’Driscoll, O’Driscoll, O’Loughlin, Preisler, Radostits, Rider, Shi, Smith, Tadich, Tarlton, Thoefner, Tomlinson, Watkins, Weber, Weber, Weissman, Whay, Whay, Wigmore   +59 more
core   +1 more source